Principles of Gene Manipulation and Genomics [NOOK Book]

Overview

"The increasing integration between gene manipulation and genomics is embraced in this book, Principles of Gene Manipulation and Genomics, which brings together for the first time the subjects covered by the best-selling books, Principles of Gene Manipulation and Principles of Genomic Analysis and Genomics. This new text has been comprehensively revived, updated, and rewritten to encompass within one volume, basic and advanced gene-manipulation techniques, genome analysis, genomics, transcriptomics, proteomics, and metabolomics, as well as the
... See more details below
Principles of Gene Manipulation and Genomics

Available on NOOK devices and apps  
  • NOOK Devices
  • NOOK HD/HD+ Tablet
  • NOOK
  • NOOK Color
  • NOOK Tablet
  • Tablet/Phone
  • NOOK for Windows 8 Tablet
  • NOOK for iOS
  • NOOK for Android
  • NOOK Kids for iPad
  • PC/Mac
  • NOOK for Windows 8
  • NOOK for PC
  • NOOK for Mac
  • NOOK Study
  • NOOK for Web

Want a NOOK? Explore Now

NOOK Book (eBook)
$73.99
BN.com price
(Save 42%)$128.95 List Price
Note: This NOOK Book can be purchased in bulk. Please email us for more information.

Overview

"The increasing integration between gene manipulation and genomics is embraced in this book, Principles of Gene Manipulation and Genomics, which brings together for the first time the subjects covered by the best-selling books, Principles of Gene Manipulation and Principles of Genomic Analysis and Genomics. This new text has been comprehensively revived, updated, and rewritten to encompass within one volume, basic and advanced gene-manipulation techniques, genome analysis, genomics, transcriptomics, proteomics, and metabolomics, as well as the applications of these fascinating technologies." Principles of Gene Manipulation and Genomics is an accessible and up-to-date guide to this exciting field, and is the essential reference for upper-level undergraduate and graduate students of genetics, genomics, molecular biology, and recombinant DNA technology.
Read More Show Less

Editorial Reviews

From the Publisher

"Principles of Gene Manipulation and Genomics is well written and clearly illustrated throughout, as would be expected from these authors who have considerable experience in this subject."
Genetical Research

Read More Show Less

Product Details

  • ISBN-13: 9781118653883
  • Publisher: Wiley, John & Sons, Incorporated
  • Publication date: 5/28/2013
  • Sold by: Barnes & Noble
  • Format: eBook
  • Edition number: 7
  • Pages: 672
  • File size: 14 MB
  • Note: This product may take a few minutes to download.

Meet the Author

Sandy Primrose was an academic for 10 years and a senior manager in the biotechnology industry for 20 years. He now manages a consultancy practice focused on technology management.

Richard Twyman worked as a research scientist at the University of Warwick and at the MRC Laboratory of Molecular Biology in Cambridge before taking up scientific writing as a full time occupation in 1998. He is currently a Visiting Fellow at the Department of Biology, University of York, and a freelance scientific writer and teacher.

Read More Show Less

Table of Contents

1 Gene manipulation in the post-genomics era 1
2 Basic techniques 15
3 Cutting and joining DNA molecules 36
4 Basic biology of plasmid and phage vectors 55
5 Cosmids, phasmids, and other advanced vectors 75
6 Gene-cloning strategies 96
7 Sequencing genes and short stretches of DNA 126
8 Changing genes : site-directed mutagenesis and protein engineering 141
9 Bioinformatics 157
10 Cloning in bacteria other than Escherichia coli 179
11 Cloning in Saccharomyces cerevisiae and other fungi 202
12 Gene transfer to animal cells 218
13 Genetic manipulation of animals 251
14 Gene transfer to plants 274
15 Advanced transgenic technology 299
16 The organization and structure of genomes 323
17 Mapping and sequencing genomes 346
18 Comparative genomics 373
19 Large-scale mutagenesis and interference 394
20 Analysis of the transcriptome 407
21 Proteomics I - expression analysis and characterization of proteins 425
22 Proteomics II - analysis of protein structures 441
23 Proteomics III - protein interactions 453
24 Metabolomics and global biochemical networks 472
25 Applications of genomics : understanding the basis of polygenic disorders and identifying quantitative trait loci 485
26 Applications of recombinant DNA technology 508
Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)