Principles of Mass Spectrometry Applied to Biomolecules / Edition 1

Hardcover (Print)
Buy New
Buy New from BN.com
$173.59
Used and New from Other Sellers
Used and New from Other Sellers
from $178.18
Usually ships in 1-2 business days
(Save 16%)
Other sellers (Hardcover)
  • All (4) from $178.18   
  • New (3) from $178.18   
  • Used (1) from $223.74   

Overview

An extensive compilation of articles by leading professionals, this reference explains the fundamental principles of mass spectrometry as they relate to the life sciences. Topics covered include spectroscopy, energetics and mechanisms of peptide fragmentation, electron capture dissociation, ion-ion and ion-molecule reactions, reaction dynamics, collisional activation, soft-landing, protein structure and interactions, thermochemistry, and more. The book empowers readers to develop new ways of using these techniques.

Read More Show Less

Editorial Reviews

From the Publisher
"this is a very impressive volume, which I recommend to anyone interested in fundamental principles governing peptide and protein ion behavior in the gas phase."  (Journal of the American Chemical Society, April 4, 2007)

"...the book is well written with numerous companion figures and tables and extensive up-to-date references..."  (Journal of the American Society for Mass Spectrometry, April 2007)

Read More Show Less

Product Details

Meet the Author

JULIA LASKIN, PHD, is a Senior Research Scientist in the Fundamental Sciences Division at the Pacific Northwest National Laboratory in Richland, Washington.

The late CHAVA LIFSHITZ, PHD, was an Archie and Marjorie Sherman Professor of Chemistry in the Department of Physical Chemistry at The Hebrew University in Jerusalem, Israel. She was also on the editorial boards of Mass Spectrometry Reviews and the International Journal of Mass Spectrometry.

Read More Show Less

Table of Contents

Contributors.

Preface.

STRUCTURES AND DYNAMICS OF GAS-PHASE BIOMOLECULES.

1. Spectroscopy of neutral Peptides in the Gas Phase-Structure, Reactivity, Microsolvation, Molecular Recognition (M. Gerhards).

2. Probing the Electronic Structure of Fe-S Clusters Using Anoin Photoelectron Spectroscopy: Ubiquitous Electron Transfer Centers in Metalloproteins (X. Yang, et al.).

3. Ion/Molecule Reactions and H/D Exchange for Structural Characterization of Biomolecules (M. Green & C. Lebrilla).

4. Understanding Protein Interactions and their Representation in the Gas Phase of the Mass Spectrometer (F. Sobott & C. Robinson).

5. Protein Structure and Folding in the Gas Phase: Ubiquitin and Cytochrome c (K. Breuker).

6. Dyunamical Simulations of Photoionization of Small Biological Molecules (D. Shemesh & R. Gerber).

7. IVR and Ergodicity of Dissociation of Bio-Molecules (C. Lifshitz).

PART II: ACTIVATION, DISSOCIATION AND REACTIVITY.

8. Mechanisms of Peptide Fragmentation (V. Wysocki, et al.).

9. Peptide Radical Cations (A. Hopkinson & K. Siu).

10. Photodissociation of Biomolecule Ions: Progress, Possibilities, and the Perspectives Coming From Small-Ion Models (R. Dunbar).

11. Chemical Dynamics Simulations of EnergyTransfer and Unimolecular Decomposition in Collision-Induced Dissociation (CID) and Surface-Induced Dissociation (SID) (A. Rahaman, et al.).

12. Ion Soft Landing: Instrumentation, Phenomena and Applications (B. Gologan, et al.).

13. Electron Capture Dissociation and Other Ion-electron Fragmentation Reactions (R. Zubarev).

14. Biomolecule Ion/Ion Reactions (S. McLuckey).

PART III: THERMOCHEMISTRY AND ENERGETICS.

15. Thermochemistry Studies of Biomolecules (C. Wesdemiotis).

16. Energy and Entropy Effects in the Gas Phase Dissociation of Peptides and Proteins (J. Laskin).

Index.

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)