Principles of Medical Biochemistry: With STUDENT CONSULT Online Access / Edition 2

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"Highly Commended," Basic and Clinical Sciences Category, British Medical Association 2012 Medical Book Competition

  • Access the fully searchable text online at, along with downloadable illustrations, 150 USMLE-style test questions, 20 clinical case studies, chapter summaries, and integration links to related subjects.
  • Understand biochemistry, cell biology, and genetics together in context through an integrated approach.
  • Get only the information you need for your course with comprehensive yet focused coverage of relevant topics.
  • Review and reinforce your learning using the glossary of technical terms, highlighted in the text and with interactive features online.
  • Tap into the most up-to-date coverage of new developments in genome research, the molecular basis of genetic diseases, techniques of DNA sequencing and molecular diagnosis, RNA interference as a mechanism both for regulation of gene expression and for anti-viral defense, and more.
  • Gain a clear visual understanding through new and updated figures that provide current and relevant guidance.
  • Make the link between basic science and clinical medicine with new Clinical Example boxes in nearly every chapter.

Focus on the most essential biochemistry principles and how they apply to clinical medicine

The book contains both black-and-white and two-color illustrations.

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Editorial Reviews

Doody's Review Service
Reviewer: Eugene A Davidson, PhD (Georgetown University School of Medicine)
Description: This is intended to serve as a text for a course in medical biochemistry. Topical coverage reflects what is usually taught. The first edition was published in 1998.
Purpose: The goal is to provide a slimmed-down version of a biochemistry text that will be more accessible to medical students. Given the encyclopedic nature of standard texts in this area, this is a worthwhile objective. This book can be considered a partial success.
Audience: The target audience is the student taking medical biochemistry. The level seems about correct but the material could be readily managed by most senior undergraduates. The authors have had experience in teaching this material in a medical school environment.
Features: Texts most often cited/suggested/assigned for student use in a medical biochemistry course are large compendia, frequently a thousand pages or more, lavishly illustrated and possessing far more information than needed. This book represents an effort to edit down the material, thus allowing the student to focus on essential items. The organization of the book presumably follows the courses taught in the home institution of the authors, starting with structural considerations, followed by discussions of information flow, cell and tissue organization, and metabolism. Each chapter has a few multiple choice questions (answers at the end of the book) and a short supplemental reading list. The latter could not be considered bibliographic and would short change the student interested in more detailed knowledge. There is a reasonably complete glossary and a useful index. Although thorough knowledge of the contents would serve most students, there is little challenge in the text, a problem especially true for the study questions. Clinical relevance is occasional and somewhat insufficient given the trend towards greater integration of clinical and basic science material. The goal of content reduction is good, but this effort only partially succeeds.
Assessment: This is a moderate effort to solve a real problem. Organization of the material is not optimal and opportunities for clinical integration are missed. New information in the last eight years does justify a new edition.
Anatoly Bezkorovainy
This is a medical biochemistry text. It is writtenfor the medical and possibly other health sciences students. Thispurpose has been achieved; the book emphasizes physiological andtherapeutic/diagnostic aspects of the material, and I have observed fewif any mechanisms from an organic chemist's point of view. Theaudience is students of medicine, veterinary science, podiatry, etc.,and even undergraduates preparing themselves for medical school. Thisbook is quite appropriate for them; it is written at the appropriatelevel and contains material of significance for this type of anaudience. I noted few significant omissions. The authors have done agood job. There is a glossary of terms, which is helpful. The indexand table of contents are adequate. There are numerous illustrationsusing various shades of blue and gray. These are useful and adequate. The soft cover has a nice/attractive design on it. The medical studentshould be able to afford this book. There are some questions at theend of each chapter, most of them multiple choice. If the purpose ofthese questions is to review the material or to test the student'sknowledge, the number of such questions is woefully inadequate. Otherwise, the book is fun to read and I would recommend it as a textfor medical biochemistry. On the other hand, there are now so manysuch books on the market that it is hard to see how this one issuperior to most of them (e.g., Roskoski'Biochemistry (WB Saunders, 1996) orChampe/Harvey's Lippincott's Illustrated Reviews:Biochemistry, 2nd edition (JB Lippincott1994).

3 Stars from Doody
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Product Details

  • ISBN-13: 9780323029421
  • Publisher: Elsevier Health Sciences
  • Publication date: 1/19/2006
  • Edition description: Older Edition
  • Edition number: 2
  • Pages: 696
  • Product dimensions: 8.46 (w) x 10.84 (h) x 1.05 (d)

Table of Contents

Ch. 1 Introduction to biomolecules 3
Ch. 2 Introduction to protein structure 19
Ch. 3 Oxygen transporters : hemoglobin and myoglobin 33
Ch. 4 Enzymatic reactions 43
Ch. 5 Coenzymes 61
Ch. 6 DNA, RNA, and protein synthesis 71
Ch. 7 Viruses 103
Ch. 8 The human genome 119
Ch. 9 Protein targeting 143
Ch. 10 Introduction to genetic diseases 153
Ch. 11 DNA technology 169
Ch. 12 Biological membranes 199
Ch. 13 The cytoskeleton 217
Ch. 14 The extracellular matrix 233
Ch. 15 Plasma proteins 255
Ch. 16 Extracellular messengers 287
Ch. 17 Intracellular messengers 313
Ch. 18 Cellular growth control and cancer 335
Ch. 19 Digestive enzymes 363
Ch. 20 Introduction to metabolic pathways 371
Ch. 21 Glycolysis, tricarboxylic acid cycle, and oxidative phosphorylation 377
Ch. 22 Carbohydrate metabolism 407
Ch. 23 The metabolism of fatty acids and triglycerides 429
Ch. 24 The metabolism of membrane lipids 447
Ch. 25 Lipid transport 461
Ch. 26 Amino acid metabolism 479
Ch. 27 Heme metabolism 503
Ch. 28 The metabolism and purines and pyrimidines 511
Ch. 29 Vitamins and minerals 523
Ch. 30 Integration of metabolism 549
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