Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy / Edition 2
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Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy / Edition 2

by David E. Golan, April W. Armstrong, Armen H. Tashijan
     
 

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ISBN-10: 0781783550

ISBN-13: 9780781783552

Pub. Date: 05/28/2007

Publisher: Lippincott Williams & Wilkins

This primary textbook for a first course in pharmacology offers an integrated, systems-based, and mechanism-based approach to understanding drug therapy. Each chapter focuses on a target organ system, begins with a clinical case, and incorporates cell biology, biochemistry, physiology, and pathophysiology to explain how and why different drug classes are effective

Overview

This primary textbook for a first course in pharmacology offers an integrated, systems-based, and mechanism-based approach to understanding drug therapy. Each chapter focuses on a target organ system, begins with a clinical case, and incorporates cell biology, biochemistry, physiology, and pathophysiology to explain how and why different drug classes are effective for diseases in that organ system.

Over 400 two-color illustrations show molecular, cellular, biochemical, and pathophysiologic processes underlying diseases and depict targets of drug therapy. Each Second Edition chapter includes a drug summary table presenting mechanism, clinical applications, adverse effects, contraindications, and therapeutic considerations. New chapters explain how drugs produce adverse effects and describe the life cycle of drug development.

The fully searchable online text and an image bank are available on thePoint.

Product Details

ISBN-13:
9780781783552
Publisher:
Lippincott Williams & Wilkins
Publication date:
05/28/2007
Edition description:
Second Edition
Pages:
985
Product dimensions:
8.60(w) x 10.70(h) x 1.20(d)

Table of Contents

FUNDAMENTAL PRINCIPLES OF PHARMACOLOGY
Drug-Receptor Interactions
Pharmacodynamics
Pharmacokinetics
Drug Metabolism
Drug Toxicity

PRINCIPLES OF NEUROPHARMACOLOGY

Fundamental Principles of Neuropharmacology
Principles of Cellular Excitability and Electrochemical Transmission
Principles of Nervous System Physiology and Pharmacology

Principles of Autonomic and Peripheral Nervous System Pharmacology
Cholinergic Pharmacology
Adrenergic Pharmacology
Local Anesthetic Pharmacology

Principles of Central Nervous System Pharmacology
Pharmacology of GABAergic and Glutamatergic Neurotransmission
Pharmacology of Dopaminergic Neurotransmission
Pharmacology of Central Adrenergic and Serotonergic Neurotransmission
Pharmacology of Abnormal Electrical Neurotransmission in the Central Nervous System
General Anesthetic Pharmacology
Pharmacology of Analgesia
Pharmacology of Drug and Alcohol Abuse and Dependence

PRINCIPLES OF CARDIOVASCULAR PHARMACOLOGY
Pharmacology of Cardiac Rhythm
Pharmacology of Cardiac Contractility
Pharmacology of Volume Regulation
Pharmacology of Vascular Tone
Pharmacology of Hemostasis and Thrombosis
Pharmacology of Cholesterol and Lipoprotein Metabolism
Integrative Cardiovascular Pharmacology: Hypertension, Ischemic Heart Disease, and Heart Failure

PRINCIPLES OF ENDOCRINE PHARMACOLOGY
Pharmacology of the Hypothalamus and Pituitary Gland
Pharmacology of the Thyroid Gland
Pharmacology of the Adrenal Cortex
Pharmacology of Reproduction
Pharmacology of the Endocrine Pancreas
Pharmacology of Bone Mineral Homeostasis

PRINCIPLES OF CHEMOTHERAPY
Principles of Antimicrobial and Antineoplastic Pharmacology
Pharmacology of Bacterial Infections: Central Dogma Processes
Pharmacology of Bacterial Infections: Cell Wall Synthesis
Pharmacology of Fungal Infections
Pharmacology of Parasitic Infections
Pharmacology of Viral Infections
Pharmacology of Cancer: DNA Synthesis, Stability, and Maintenance
Pharmacology of Cancer: Signal Transduction
Principles of Combination Chemotherapy

PRINCIPLES OF INFLAMMATION AND IMMUNE PHARMACOLOGY
Principles of Inflammation and the Immune System
Pharmacology of Eicosanoids
Histamine Pharmacology
Pharmacology of Hematopoietic and Immune Cell Stimulation
Pharmacology of Immunosuppression
Integrative Inflammation Pharmacology: Peptic Ulcer Disease
Integrative Inflammation Pharmacology: Asthma
Integrative Inflammation Pharmacology: Gout

FUNDAMENTALS OF DRUG DEVELOPMENT AND REGULATION
Drug Discovery and Preclinical Development
Clinical Drug Evaluation and Regulatory Approval
Detection and Management of Adverse Events in Marketed Drugs

POISONING BY DRUGS AND ENVIRONMENTAL TOXINS

FRONTIERS IN PHARMACOLOGY
Pharmacogenomics
Protein-Based and Gene Therapies
Drug Delivery Modalities

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