Probability Models for DNA Sequence Evolution / Edition 2

Probability Models for DNA Sequence Evolution / Edition 2

by Richard Durrett
     
 

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ISBN-10: 0387781684

ISBN-13: 9780387781686

Pub. Date: 06/28/2008

Publisher: Springer New York

Second edition of a successful book covering genetics, one of the fastest growing areas of active research Author Durrett is a very well-known probabilist Assumes no previous knowledge of biology and only a basic knowledge of probability Includes data from numerous experimental studies from the biological literature How is genetic variability shaped by natural

Overview

Second edition of a successful book covering genetics, one of the fastest growing areas of active research Author Durrett is a very well-known probabilist Assumes no previous knowledge of biology and only a basic knowledge of probability Includes data from numerous experimental studies from the biological literature How is genetic variability shaped by natural selection, demographic factors, and random genetic drift? To approach this question, we introduce and analyze a number of probability models beginning with the basics, and ending at the frontiers of current research. Throughout the book, the theory is developed in close connection with examples from the biology literature that illustrate the use of these results. Along the way, there are many numerical examples and graphs to illustrate the conclusions. This is the second edition and is twice the size of the first one. The material on recombination and the stepping stone model have been greatly expanded, there are many results form the last five years, and two new chapters on diffusion processes develop that viewpoint. This book is written for mathematicians and for biologists alike. No previous knowledge of concepts from biology is assumed, and only a basic knowledge of probability, including some familiarity with Markov chains and Poisson processes. The book has been restructured into a large number of subsections and written in a theorem-proof style, to more clearly highlight the main results and allow readers to find the results they need and to skip the proofs if they desire. Written for: Researchers, graduate students

Product Details

ISBN-13:
9780387781686
Publisher:
Springer New York
Publication date:
06/28/2008
Series:
Probability and Its Applications Series
Edition description:
2nd ed. 2008
Pages:
431
Product dimensions:
6.30(w) x 9.30(h) x 1.00(d)

Table of Contents

Basic models - Estimation and hypothesis testing - Recombination - Population complications - Stepping stone model - Natural selection - Diffusion process - Multidimensional diffusions - Genome rearrangement.

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