Proceedings of the Third International Conference on Intelligent Systems for Molecular Biology

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Product Details

  • ISBN-13: 9780929280837
  • Publisher: AAAI Press
  • Publication date: 8/28/1995
  • Pages: 512

Table of Contents

Sponsors
Program Committee
Preface
Protein Docking Combining Symbolic Descriptions of Molecular Surfaces and Grid-Based Scoring Functions 3
Characterizing Oriented Protein Structural Sites Using Biochemical Properties 12
The Value of Prior Knowledge in Discovering Motifs with MEME 21
Periodic Sequence Patterns in Human Exons 30
Protein Modeling with Hybrid Hidden Markov Model/Neural Network Architectures 39
Viewing Genome Data as Objects for Application Development 48
APIC: A Generic Interface for Sequencing Projects 57
A Specification for Defining and Annotating Regions of Macromolecular Structures 66
Graph-Theoretic Approach to RNA Modeling Using Comparative Data 75
Predicting Free Energy Contributions to the Conformational Stability of Folded Proteins from the Residue Sequence with Radial Basis Function Networks 81
Recognising Promoter Sequences Using Artificial Immune System 89
Predicting Protein Folding Classes without Overly Relying on Homology 98
A Divide and Conquer Approach to Multiple Alignment 107
Multiple Alignment Using Hidden Markov Models 114
Symbolic Generation and Clustering of RNA 3-D Motifs 121
Reconstruction of Metabolic Networks Using Incomplete Information 127
Automatic RNA Secondary Structure Determination with Stochastic Context-Free Grammars 136
Parallel Sequence Alignment in Limited Space 145
Neural Net Representations of Empirical Protein Potentials 154
Classifying Nucleic Acid Sub-Sequences as Introns or Exons Using Genetic Programming 162
Constituting a Receptor-Ligand Information Base from Quality-Enriched Data 170
3-D Lookup: Fast Protein Structure Database Searches at 90% Reliability 179
Evaluating Regularizers for Estimating Distributions of Amino Acids 188
Computer Tool FUNSITE for Analysis of Eukaryotic Regulatory Genomic Sequences 197
Identification of CDNA Sequences by Specific Oligonucleotide Sets - A Computer Tool and Application 206
Maximum Entropy Weighting of Aligned Sequences of Proteins or DNA 215
An Optimized Parsing Algorithm Well Suited to RNA Folding 222
A Constraint-Based Assignment System for Automating Long Side Chain Assignments in Protein 2D NMR Spectra 231
Relation Between Protein Structure, Sequence Homology and Composition of Amino Acids 240
Cooperative Computer System for Genome Sequence Analysis 249
MMDB: An ASN.1 Specification for Macromolecular Structure 259
Softening Constraints in Constraint-Based Protein Topology Prediction 268
DNA Sequence Assembly and Genetic Algorithms - New Results and Puzzling Insights 277
A New Approach to Primer Selection in Polymerase Chain Reaction Experiments 285
Investigations of Escherichia coli Promoter Sequences with Artificial Neural Networks: New Signals Discovered Upstream of the Transcriptional Startpoint 292
Time-Efficient Docking of Flexible Ligands into Active Sites of Proteins 300
Subclass Approach for Mutational Spectrum Analysis 309
TOPITS: Threading One-Dimensional Predictions into Three-Dimensional Structures 314
A Distance-Based Block Searching Algorithm 322
Using Temporal Reasoning for Genome Map Assembly 332
Automata - Theoretic Models of Mutation and Alignment 341
Solvent Accessible Surface Representation in a Database System for Protein Docking 350
BONSAI Garden: Parallel Knowledge Discovery System for Amino Acid Sequences 359
Identification of Human Gene Structure Using Linear Discriminant Functions and Dynamic Programming 367
Towards an Intelligent System for the Automatic Assignment of Domains in Globular Proteins 376
Recursive Dynamic Programming for Adaptive Sequence and Structure Alignment 384
Neweyes: A System for Comparing Biological Sequences Using the Running Karp-Rabin Greedy String-Tiling Algorithm 393
Identification of Protein Motifs Using Conserved Amino Acid Properties and Partitioning Techniques 402
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