Prognostic Factors in Cancer

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Prognostic Factors in Cancer, Third Edition amends and streamlines the authoritative monograph on prognostic factors and their use in planning treatment for cancer patients. The text is an extension of the International Union Against Cancer's (UICC) seminal work, the TNM Classification of Malignant Tumours, and integrates the current focus on prognostics in cancer. The Tumor-Node-Metastasis (TNM) classification remains the most widely used system for staging the progression of cancer and is the single most ...
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Overview

Prognostic Factors in Cancer, Third Edition amends and streamlines the authoritative monograph on prognostic factors and their use in planning treatment for cancer patients. The text is an extension of the International Union Against Cancer's (UICC) seminal work, the TNM Classification of Malignant Tumours, and integrates the current focus on prognostics in cancer. The Tumor-Node-Metastasis (TNM) classification remains the most widely used system for staging the progression of cancer and is the single most important predictive indicator for outcomes.

Prognostic Factors in Cancer, Third Edition is divided into two parts. The first section provides an update on the science of prognosis in general and prognosis in cancer patients in particular, including issues surrounding accuracy of measurement of prognosis and methodology of studying and classifying prognostic factors. That section also introduces the timely topic of incorporating molecular oncology into prognosis. The second section consists of site-specific or tumor-specific chapters and the prognostic factors associated with particular malignancies. These chapters contain an overview of the relevant literature and include tables that classify prognostic factors according to variable circumstances (tumor and non-tumor subjects) and relevance.

Prognostic Factors in Cancer, Third Edition illustrates the scope of the field as it stands today. It imparts a perspective on likely outcomes of neoplastic disease that is an increasingly useful tool for physicians and all others responsible for the care of patients with cancer.

This book updates the first authoritative monograph on prognostic factors and their use in planning treatment for cancer patients. This text is an extension of studies undertaken by the International Union Against Cancer (UICC) in relation to their long-term work on the TNM Classification of Malignant Tumours. The TNM classification internationally is the most widely used system for staging the progression of cancer. The TNM system offers the most accurate tool for predicting outcomes for most tumour sites and certain tymour types. The chapters included contain an overview of the relevant literature and include summaries that classify the prognostic factors according to subject or topic, and relevance.

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Editorial Reviews

Doody's Review Service
Reviewer: Kenneth R. Carson, MD (Northwestern University Feinberg School of Medicine)
Description: This update provides a comprehensive review of the methods of determining prognosis and their clinical use with numerous tumor types.
Purpose: The intent with this new edition is to consolidate previous work in prognosis and prognostic factors, facilitating their use in clinical practice. These are worthy objectives, as patients with cancer and their physicians often struggle with providing realistic prognostic advice. Prognosis is often a lost art in the practice of modern, evidence-based medicine. The authors deliver exactly what they intended.
Audience: This book is targeted at clinicians and researchers in the field of oncology. Each of the authors and editors is a credible authority in his or her respective field.
Features: A well written description of the background and methods used to determine prognosis, including anatomic, histologic, and genetic prognostic factors, begins the book. The book is then divided into disease specific chapters with prognostic information related to each disease type. Each of these chapters contains a table for quick reference, which is helpful for busy clinicians.
Assessment: This is a well organized and reasonably comprehensive book. While the use of genetic prognostic factors is not explained comprehensively for all tumor types, the usefulness of this information is still being determined for many tumors. The book provides a quick reference that brings together state-of-the-art knowledge for numerous tumor types. The inclusion of genetic prognostic information for some tumor types as well as information on prognosis in the terminal setting, provides additional value in this third edition.
From the Publisher
"Recommended for the medical profession[al] dealing with cancer patients." (E-STREAMS, June 2007)

"This is a well organized and…comprehensive book…a quick reference that brings together state-of-the-art knowledge for numerous tumor types." (Doody's Health Services)

"…one of only textbooks of its kind to focus on the clinical methodology for evaluating prognostic factors in order to arrive at humane and effective treatments for the cancer-sick patient." (Electric Review, September/October 2006)

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Product Details

  • ISBN-13: 9780471406334
  • Publisher: Wiley, John & Sons, Incorporated
  • Publication date: 1/28/2001
  • Edition description: REV
  • Edition number: 2
  • Pages: 832
  • Product dimensions: 6.24 (w) x 9.10 (h) x 1.48 (d)

Table of Contents

1 The importance of prognosis in cancer medicine 3
2 Prognostic factors : principles and applications 23
3 Studies investigating prognostic factors : conduct and evaluation 39
4 Prognostic factors in population-based cancer control 55
5 Prognostic factors in terminal cancer 63
6 Incorporating molecular oncology into prognosis 79
7 Oral cavity, pharynx, and larynx cancer 99
8 Paranasal sinus cancer 105
9 Nasopharyngeal cancer 109
10 Salivary gland cancer 113
11 Thyroid cancer 119
12 Esophageal cancer 125
13 Gastric cancer 129
14 Colorectal cancer 133
15 Anal cancer 139
16 Hepatocellular carcinoma 143
17 Extrahepatic biliary tract and the ampulla of Vater cancers 147
18 Pancreas cancer 153
19 Lung cancer 159
20 Malignant pleural mesothelioma 165
21 Malignant thymoma 169
22 Osteosarcoma 175
23 Soft tissue sarcomas 181
24 Gastrointestinal stromal tumors 187
25 Skin cancer 195
26 Cutaneous malignant melanoma 199
27 Breast cancer 207
28 Vulvar cancer 215
29 Uterine cervix cancer 219
30 Ovarian and fallopian tube cancer 223
31 Endometrial cancer 229
32 Gestational trophoblastic disease 233
33 Penile cancer 241
34 Prostate cancer 247
35 Germ cell testis tumors 253
36 Renal cell cancer 257
37 Bladder cancer 261
38 Uveal melanoma 269
39 Retinoblastoma 273
40 Hodgkin lymphoma 281
41 Non-Hodgkin lymphomas 285
42 Leukemias 291
43 Multiple myeloma 301
44 Gliomas 307
45 Pediatric cancers 315
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