Progress in Basic and Clinical Immunology / Edition 1

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Overview

Progress in Basic and Clinical Immunology is a result of the 14th European Immunology Meeting - EFIS 2000, held in Poznan, Poland, on 23-27 September 2000. EFIS 2000 gathered over 1400 immunologists from all over the world. It was an exceptionally memorable meeting for a number of reasons: 1) it was held in the last year of the century and the millennium, thus provoking conclusions of past achievements of immunology and projections for the future; 2) it was held in Poland, a country that is a symbol of struggle for freedom for a large number of scientists originating from the 'Eastern Bloc' countries; and 3) EFIS celebrated its 25th anniversary at this occasion. This comprehensive volume contains 62 chapters grouped into 11 sections: T-cells, Immune Receptors, Antigen Presentation/Dendritic Cells, Cytokines, Immunodeficiencies, Autoimmunity, Allergy/Inflammation, Immunotherapy, Vaccines, Tumor Immunology, and Cancer Immunotherapy.

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Editorial Reviews

From The Critics
The result of the 14th European Immunology Meeting, which was held in Poland in September of 2000, this volume contains 62 papers that were developed from abstracts presented at the meeting. Selected by scientists from the Polish institutions, the University School of Medical Sciences and the Institute for Human Genetics, the papers are mostly related to tumor immunology and immunotherapy. Other topics include T-cells, immune receptors, antigen presentation/dendritic cells, cytokines, immunodeficiencies, autoimmunity, allergy/inflammation, and vaccines. Annotation c. Book News, Inc., Portland, OR
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Product Details

Table of Contents

T-Cells. CD3-dependent regulation of early TCRbeta gene expression in mainstream alphabeta and NKalphabeta T cell development; N. Baur, K. Eichmann. Molecular characterization of gut T cell precursors in in euthymic and athymic mice; F. Lambolez, B. Rocha. CRTH: marker for the detection of human Th2 and Tc2 cells; L. Cosmi, et al. GILZ, a glucocorticoid hormone induced gene, modulates T lymphocytes activation and death through interaction with NF-kB; C. Riccardi, et al. Tyrosine phosphorylation of PICOT and its translocation to the nucleus in response of human T cells to oxidative stress; Y. Babichev, N. Isakov. Immune Receptors. The molecular specificity of IgG-Fc interactions with Fcgamma receptors; Y. Mimura. Regulation of myeloid cell proliferation and survival by p75/AIRM1 and CD33 surface receptors; M.C. Mingari, et al. X-linked lymphoproliferative disease: the dark side of 2b4 function; C. Bottino, et al. Antigen Presentation / Dendritic Cells. Role of tapasin in MHC class I antigen presentation in vivo; N. Garbi, et al. Regulation of transporters associated with antigen processing (TAPs) by nucleotide binding to, and hydrolysis by, Walker consensus sequences; L. Saveanu, P.M. Van Endert. The AIR-1 encoded class II transactivator (CIITA): the master coordinator of MHC class II gene expression and ..more; R.S. Accolla. Major hisompatibility complex class II (MHC II) expression during development of human fetal brain and haemopoietic organs; T. Wierzba-Bobrowicz, et al. Interactions between dendritic cells; S.C. Knight, et al. Neural regulation of dendritic cell function; G.J.M. Maestroni. A central role for heat shock proteins in host deficiency; P.K. Srivastava. Cytokines. Allele specific regulation of cytokine genes: monoallelic expression of the IL-1A gene; C.L. Verweij, et al. Effect of polysaccharide sulfates on the production of interleukin-8 in an ex vivo model; P.P. Jagodzinski, W.H. Trzeciak. Coordination of interleukin-6 biology by membrane bound and soluble receptors; S. Rose-John. Termination and modulation of IL-6-type cytokine signaling; P.C. Heinrich, et al. Cytokine-induced STAT signalling through the cytoplasmic compartment; P.B. Sehgal. Cytokine-mediated growth inhibition of human melanoma cells; M. Kortylewski, et al. Interleukin-6, tumor necrosis factor &agr; and interferon &ggr; in patients with anorexia nervosa; R. Komorowska-Pietrzykowska, et al. Interleukin-1 system in testis &endash; quantitative analysis; N. Rozwadowska, et al. Immunodeficiences. Mapping genes underlying complex disorders: progress on IgA deficiency and common variable immunodeficiency; I. Vorechovsky, et al. Ataxia-Telangiectasia; S.G. Becker-Catania, R.A. Gatti. Gene therapy of severe combined immunodeficiencies; A. Fischer, et al. Immune reconstitution after highly active anti-retroviral treatment of HIV infection; B. Autran, et al. Dissimilarity of cinical signs with parameters characterizing immune system; N.K. Gorlina, et al. Autoimmunity. The role of Fc receptors and complement in autoimmunity; U. Baumann, R.E. Schmidt. Effect of Hsp70-peptide complexes generated in vivo on modulation EAE; G. Galazka, et al. Gene transfer of protective cytokines in rheumatoid arthritis; O. Distler, et al. Modification of humoral antisperm response; B. Grygielska, et al. Allergy / Inflammation. Immunologic mechanisms of allergen-specific immunotherapy; C.A. Akdis, K. Blaser. Phosphorothioate oligonucleotides: looking for the motif(s) possessing immunostimulatory activities in humans; F. Brugnolo, et al. Disorders in mononuclear phagocytes and reduced glutathine and their correction in Chernobyl children with recurrent respiratory infections and chronic inflammatory focal lesions; V. Chernyshov, et al. Immunotherapy. Adoptive transfer of mucosal T cells or dendritic cells from animals fed with cholera toxin B subunit alloantigen conjugate induces allogeneic T cell tolerance; B.-L. Li, et al. Total body irradiation before bone marrow transplantation: aims and results; J. Malicki, et al. Statins as immunomodulatory drugs; A. Górski, et al. Vaccinces. Phage display of epitopes from HIV-1 elicits strong cytolytic responses in vitro and in vivo; J. Guardiola, et al. Oral immunization of human with transgenic lettuce expressing hepatitis B surface antigen; J. Kapusta, et al. Nasal administration of Schistosoma Mansoni egg antigens &endash; cholera toxin B subunit conjugate to infected mice reduces immunopathology and mortality; J.-B. Sun, et al. Anti-influenza vaccination changes expression of CD45 isoforms on peripheral blood NK cells of the elderly; A. Myśliwski, et al. Tumor Immunology. Presence and functions of immune components in the tumor microenvironment; I.P. Witz. Expression of TCR &xgr; chain of tumor associated lymphocytes from malignant pleural effusions; J. Sikora, et al. Cyhrome c is rapidly extruded from apoptotic cells and detectable in serum of anticancer-drug treated tumor patients; A. Renz, et al. CD 56 (N-CAM) antigen and mRNA expression in human endocrine glands; J. Żeromski, et al. Cancer Immunotherapy. Glycodendrimeric ligands of C-type lectin receptors as therapeutic agents in experimental cancer; M. Pospišil, et al. Exosomes in cancer immunotherapy: preclinical data; F. Andre, et al. Bone marrow dendritic cell-based anticancer vaccines; M. Indrová, et al. Dendritic cell-based vaccines for therapy of HPv16-induced tumours; J. Bubeník, et al. Cytokine gene transfection for autologous and allogeneic melanoma vaccines; S. Todryk, et al. Brain tumor treatment with IL-2 and IL-12 producing autologous cancer cell vaccines; S. Desaknai, et al. IL-II is a potent anti-melanoma factor; H. Dams-Kozlowska, et al. IL-6 and GM-CSF in tumor rejection model of renal cell cancer; P.J. Wysocki, et al. The effects of peritumoral therapeutic vaccination with IL-2-secreting cells on growth of MC38 colon tumours in mice, local NO production and sentinel lymph node cells activation; E. Pajtasz-Piasecka, et al. Improving the retroviral vector (RV) systems for immunotherapy of cancer; P. Grabarczyk, et al. Tumor immunity in mice immunized with fibroblasts transfected with tumor DNA; E.F. De Zoeten, et al. T cell response to tumor antigens and its therapeutic use in cancer patients; G. Parmiani, et al. 4 Additional Chapters. Subject index. Index of authors.
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