Progress in Nucleic Acid Research and Molecular Biology

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Overview

Progress in Nucleic Acid Research and Molecular Biology provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology. It contains contributions from leaders in their fields and abundant references.

Progress in Nucleic Acid Research and Molecular Biology provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology. It contains contributions from leaders in their fields and abundant references.

Audience: Biochemists, molecular biologists, geneticists, and cell biologists.

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Editorial Reviews

From The Critics
Full of interest not only for the molecular biologist — for whom the numerous references will be invaluable — but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell.
Howard H. Sky-Peck
This is an up-to-date review of the state-of-the-art in research of the structure and function of large molecules such as proteins, RNA, DNA, viruses, ferritin, and various subjects related to replication and control of living organisms. "The purpose is to review a number of research areas dealing with molecular biology of nucleoproteins, nucleic acids, and interaction both in vivo and in vitro. "The volume is directed at those individuals working in the area of macromolecules, their structure and functions. The articles are aimed at biochemists, molecular biologists working in these fields, and graduate students learning the subject in class or laboratory. "Included are discussions of global gene regulation in E.coli; the structure and function of eukaryotic nuclear RNase and its ability to self-splice and cleave various t-RNAs; feritin, a multimeric iron-storage protein and its regulation of synthesis coupled with iron concentration that affects m-RNA; and the effect of parvoviruses and other linear DNA genome viruses causing changes in DNA structure in insects and vertebrates. "I enjoyed this book. It is an excellent review of a number of interesting topics. However, I would criticize the lack of sufficient diagrams to describe the three-dimensional structures in relation to function. There is, unfortunately, no glossary to interpret the many acronyms used in the various articles. In spite of this, I highly recommend this book for libraries and scientific personnel working in the field.
Philip M. Sass
This volume is a compilation of disparate, apparently unrelated chapters that cover a wide range of topics, including nucleic acid structure, gene expression of the malic enzyme, antisense technology, and control of translational stop signals in prokaryotes and eukaryotes. "The book does not contain a preface and it is unclear what the purpose of the book is. "With no preface, the book also lacks a discussion of the target audience for which the book is intended. However, the target audience for this book is very limited, because the book lacks a coherent theme. "The various chapters are well written and for the most part very informative. For example, there is a very interesting theoretical discussion on the intricacies of the mechanics of translational stop codons. "I would recommend purchase of this book only by libraries, because the book contains chapters that cover so many different topics.
British Medical Journal
Full of interest not only for the molecular biologist—for whom the numerous references will be invaluable—but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell.
Eugene A. Davidson
This latest volume in a long-running series includes ten authoritative reviews on diverse subjects concerned with aspects of nucleic acid metabolism. "It is intended as a review for active investigators. "Researchers in this area are the audience. "Several of the articles are interrelated: the role of PriA in replication and recombination, genetic diseases of DNA repair, recombinational repair and RecA, and genetic disorders which lead to genomic instability and cancer. Aspects of development are discussed in chapters on retinoic acid and pituitary development. Additionally, syndecan expression and cyclic nucleotide phosphodiesterases are discussed. Each article is accompanied by a useful, detailed bibliography and can serve as a reference source and up-to-date compilation of work in the noted areas. "Investigators working in these areas will want access to this material. The volume would be improved if the editor had provided some prefatory remarks linking related materials and providing an overall theme.
Booknews
Volume 44 of the series comprises seven articles on structure and action of mammalian ribonuclease (angiogenin) inhibitor; bacterial adenylyl cyclases; initiation of transcription by RNA polymerase II--a multi-step process; regulation of repair of alkylation damage in mammalian genomes; cell delivery and mechanisms of action of antisense oligonucleotides; enzyme organization in DNA precursor biosynthesis; and identification and characterization of novel substrates for protein tyrosine kinases. Annotation c. Book News, Inc., Portland, OR (booknews.com)
From The Critics
Reviewer: Eugene A Davidson, PhD (Georgetown University School of Medicine)
Description: This latest volume in a long-running series includes ten authoritative reviews on diverse subjects concerned with aspects of nucleic acid metabolism.
Purpose: It is intended as a review for active investigators.
Audience: Researchers in this area are the audience.
Features: Several of the articles are interrelated: the role of PriA in replication and recombination, genetic diseases of DNA repair, recombinational repair and RecA, and genetic disorders which lead to genomic instability and cancer. Aspects of development are discussed in chapters on retinoic acid and pituitary development. Additionally, syndecan expression and cyclic nucleotide phosphodiesterases are discussed. Each article is accompanied by a useful, detailed bibliography and can serve as a reference source and up-to-date compilation of work in the noted areas.
Assessment: Investigators working in these areas will want access to this material. The volume would be improved if the editor had provided some prefatory remarks linking related materials and providing an overall theme.
From the Publisher
Praise for the Serial:
"Full of interest not only for the molecular biologist - for whom the numerous references will be invaluable - but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell."
-British Medical Journal

3 Stars from Doody
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Product Details

  • ISBN-13: 9780125400725
  • Publisher: Elsevier Science
  • Publication date: 8/14/2002
  • Pages: 485

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Compilation of reviews on topics in molecular biology.
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Table of Contents

Viral Strategies of Translation initiation: Ribosomal Shunt and Reinitiation.
Initiation of Eukaryotic DNA Replication- Regulation and Mechanisms.
Deoxyribonucleotide Synthesis in Anaerobic Microorganisms: The Class III Ribonucleotide Reductase.
Regulation of Pathways of mRNA Destabilization and Stabilization.
Jasmonates and Octadecanoids - Signals in Plant Stress Responses and Development.
The Ubiquitous nature of RNA Chaperone Proteins.
Mechanisms of basal and kinase-inducible transcription activation by CREB.
eIF4A: The Godfather of the DEAD box Helicases.
CTD phosphatase, role in RNA polymerase II cycling and the regulation of transcript elongation.
Translational control of gene expression: role of IRESes and consequences on cell transformation and angiogenesis.
Structure and Function of Hexameric RNA to Drive Viral DNA Packaging Motor.

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