Protein Geometry, Classification, Topology and Symmetry: A Computational Analysis of Structure

by William R. Taylor, Andras Aszodi

Overview

From a geometric perspective, this book reviews and analyzes the structural principals of proteins with the goal of revealing the underlying regularities in their construction. It also reviews computer methods for structure analysis and the automatic comparison and classification of these structures with an analysis of the statistical significance of comparing different shapes. Following an analysis of the current state of the protein classification, the authors explore more abstract geometric and topological representations, including the occurrence of knotted topologies. The book concludes with a consideration of the origin of higher-level symmetries in protein structure.

Product Details

ISBN-13:	9781040208441
Publisher:	CRC Press
Publication date:	10/01/2004
Series:	Series in Biophysics
Sold by:	Barnes & Noble
Format:	eBook
Pages:	348
File size:	18 MB
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About the Author

Taylor, William R.; Aszodi, Andras

Table of Contents

1 Introduction PART 1 - GEOMETRY: Ellipsoids and embedding. Sticks to strings. PART 2 - CLASSIFICATION: Networks and domains. Protein structure comparison. Classiffcation and fold spaces. PART 3 - TOPOLOGY: Folds, tangles and knots. Structure prediction and modelling. PART 4 - SYMMETRY: Structural symmetry. Evolution and Origins. References. Index.