Protein-Protein Interactions in Drug Discovery
  • Protein-Protein Interactions in Drug Discovery
  • Protein-Protein Interactions in Drug Discovery

Protein-Protein Interactions in Drug Discovery

by Alexander Domling
     
 

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Treating protein-protein interactions as a novel and highly promising class of drug targets, this volume introduces the underlying strategies step by step, from the biology of PPIs to biophysical and computational methods for their investigation.

The main part of the book describes examples of protein targets for which small molecule modulators have been

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Overview

Treating protein-protein interactions as a novel and highly promising class of drug targets, this volume introduces the underlying strategies step by step, from the biology of PPIs to biophysical and computational methods for their investigation.

The main part of the book describes examples of protein targets for which small molecule modulators have been developed, covering such diverse fields as cancer, autoimmune disorders and infectious diseases. Tailor-made for the practicing medicinal chemist, this ready reference includes a wide selection of case studies taken straight from the development pipeline of major pharmaceutical companies to illustrate the power and potential of this approach.

Product Details

ISBN-13:
9783527331079
Publisher:
Wiley
Publication date:
03/25/2013
Series:
Methods and Principles in Medicinal Chemistry Series, #56
Pages:
334
Product dimensions:
6.90(w) x 9.70(h) x 0.80(d)

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