Protein Purification: Design and Scale up of Downstream Processing / Edition 1

Protein Purification: Design and Scale up of Downstream Processing / Edition 1

by Scott M. Wheelwright, Wheelwright
     
 

ISBN-10: 0471037230

ISBN-13: 9780471037231

Pub. Date: 11/04/1993

Publisher: Wiley

A comprehensive introduction to the art and science used by the biochemist and process engineer in the design and optimization of large-scale protein-purification processes. Covers the basics of proteins' properties, the unit operations involved in protein purification as well as important related issues of process design, integration with upstream operations, cost

Overview

A comprehensive introduction to the art and science used by the biochemist and process engineer in the design and optimization of large-scale protein-purification processes. Covers the basics of proteins' properties, the unit operations involved in protein purification as well as important related issues of process design, integration with upstream operations, cost and timing to market. Includes an abundance of figures and tables.

Product Details

ISBN-13:
9780471037231
Publisher:
Wiley
Publication date:
11/04/1993
Pages:
244
Product dimensions:
6.36(w) x 9.69(h) x 0.72(d)

Table of Contents

Process Design and Competitive Advantage.

Strategies for Process Design.

Protein Characteristics.

Analytical Methods.

Impact of Upstream Operations.

Cell Disruption.

Centrifugation.

Precipitation and Extraction.

Filtration.

General Chromatography.

Ion Exchange Chromatography.

Hydrophobic Interaction Chromatography and Reversed Phase Chromatography.

Affinity Chromatography.

Gel Filtration Chromatography.

Large-Scale Examples.

Index.

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