Protein Structure and Protein Engineering

Overview

The main topic of this 39th Mosbacher Colloquium is concerned with techniques of protein engineering, examples of application, and the analysis and determination of protein structure, their stability and flexibility. Physicochemical aspects of hydrophobic interactions, folding dynamics, energy and entropy changes during conformational changes of peptide or protein chains, and the molecular events during catalytic processes, as well as ligand binding of a given enzyme are comprehensively treated. Furthermore, the ...
See more details below
Paperback (Softcover reprint of the original 1st ed. 1988)
$99.00
BN.com price
Other sellers (Paperback)
  • All (7) from $71.87   
  • New (6) from $71.87   
  • Used (1) from $141.00   
Sending request ...

Overview

The main topic of this 39th Mosbacher Colloquium is concerned with techniques of protein engineering, examples of application, and the analysis and determination of protein structure, their stability and flexibility. Physicochemical aspects of hydrophobic interactions, folding dynamics, energy and entropy changes during conformational changes of peptide or protein chains, and the molecular events during catalytic processes, as well as ligand binding of a given enzyme are comprehensively treated. Furthermore, the implications for designing new biologically active peptides and synthetic antibodies are discussed.
Read More Show Less

Product Details

Table of Contents

How Does ATP Make Work?.- Hydrophobic Interactions in Proteins.- Is There a Code for Protein Folding?.- The Method of Protein Structure Determination by NMR in Solution: Initial New Insights Relating to Molecular Mobility.- A Calculated Conformation for the Folding Transition State of Bovine Pancreatic Trypsin Inhibitor.- Conformational Entropy and Protein Stability.- The Improvement of Catalytic Effectiveness of an Enzyme: Pseudorevertant Triosephosphate Isomerases Obtained by Random Mutagenesis of Catalytically Sluggish Mutants.- Reaction Coordinate Approach to the Binding of Ligands to Carboxypeptidase A.- The Specific Interaction of Human Leukocyte Elastase with Various Protein Inhibitors.- The Interplay Between Enzyme Mechanism, Protein Structure, and Inhibitor and Catalyst Design.- Evolution of Hemoglobin as Studied by Protein Engineering and X-Ray Crystallography.- Design and Construction of Biologically Active Peptides and Proteins Including Enzymes.- Computer Modeling with a Protein Data Base.- Automated and High-Speed DNA Sequencing - Computer Technology Promotes Biological Advances.- Synthetic Antibodies with a Known Three-Dimensional Structure.
Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)