Psychobiology of Posttraumatic Stress Disorder: A Decade of Progress / Edition 1

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Since the New York Academy of Sciences sponsored its 1996 conference, Psychobiology of Post-Traumatic Stress Disorder (PTSD), in New York City, there have been major research advances in the understanding and treatment of this disorder. Most of the biologic findings presented at the 1996 conference in extremely preliminary form have withstood the test of time and replication, and almost without exception the researchers who presented at the previous conference are still active researchers in the field of PTSD.

The field has undergone a dramatic improvement in the quality of findings -- issues that appeared to be relatively simple ten years ago with only limited data available are now far more complex. However, strategies for examining the psychobiology of PTSD have allowed the field to keep pace with these complexities.

This volume integrates basic science and clinical research, so that both bench researchers and clinicians can develop a comprehensive understanding of recent progress in post-traumatic stress research, including its molecular biology, pathophysiology, neurology, epidemiology, clinical care, and psychosocial management.

NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit

ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order ( Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit for more information about becoming a member.

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Product Details

  • ISBN-13: 9781573316194
  • Publisher: Wiley, John & Sons, Incorporated
  • Publication date: 6/30/2006
  • Series: Annals of the New York Academy of Sciences Series , #1073
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 352
  • Product dimensions: 6.00 (w) x 9.00 (h) x 0.90 (d)

Table of Contents

Overview: Rachel Yehuda.

Part I:.

1. Examining Biological and Psychological Predictors of PTSD Using Prospective, Longitudinal Studies: Charles Marmar.

2. Longitudinal Psychophysiological Studies of Heart Rate: Mediating Effects and Implications for Treatment: Richard A. Bryant.

3. Predicting PTSD Prospectively Based on Prior Trauma History, Trauma Severity, and Immediate Biologic Responses: Douglas L. Delahanty.

4. Opioid Administration in Burn Victim Children: Implications for PTSD Pathophysiology and Prophylaxis: Glenn Saxe.

5. Efficacy of Hydrocortisone in Preventing PTSD Following Critical Illness and Major Surgery: Gustave Schelling.

Part II:.

6. Memory Performance in Older Trauma Survivors: Implications for the Longitudinal Course of PTSD: Julia Golier.

7. Hippocampal, Amygdala, and Anterior Cingulate Function in PTSD: Lisa Shin.

8. Relationship Between Cognitive and Brain Changes: J. Douglas Bremner.

9. Neural Correlates of Traumatic Memory in PTSD Using PET Neuroimagery: Israel Liberzon.

10. PTSD Symptom Provocation and Neuroimaging: Heterogeneity of Response: Ruth Lanius.

Part III:.

11. Rational Use of Endocrine Testing to Examine Glucocorticoid Responsiveness in PTSD: Rachel Yehuda.

12. Immune Function in PTSD: Margaret Altemus.

13. Exaggerated Cortisol Responses to Stress: Eric Vermetten.

14. Neuroendocrine Regulation of Sleep Disturbance in PTSD: Thomas C. Neylan.

15. Low Dose Cortisol as a Treatment for Chronic PTSD: Dominique J.-F de Quervain.

Part IV:.

16. Neurobiologic Research on Sleep and Stress Hormones in Epidemiologic Samples: Naomi Breslau.

17. Epidemiologic Approaches to the Study of Genetics and Molecular Biology of PTSD: Sandro Galea.

18. Biologic Studies of Identical and Fraternal Twins: Roger K. Pitman.

19. The Developmental Epidemiology of PTSD: Neurocognitive Self-Regulation as a Key Mechanism: Karestan C. Koenen.

20. Applying Biological Data in the Forensic and Policy Arenas: Richard J. McNally.

21. How Biological Studies in PTSD Inform Non-Pharmacologic Treatment: Bessel A. van der Kolk.

Part V:.

22. Contributions of Developmental and Basic Neuroscience to Understanding PTSD.

Psychobiological Mechanisms of Vulnerability and Resilience to Extreme Stress: Implications for Prevention and Treatment: Dennis S. Charney.

23. Neurobiological Consequences of Early Stress and Childhood Maltreatment: Are Results From Animal and Human Studies ComĀ¬parable?: Martin Teicher.

24. Epigenetic Programming by Maternal Behavior: A Mechanism for Understanding the Impact of Early Environment on Later Responses to Stress and Intergenerational Transmission of Trauma: Michael Meaney.

25. Glucocorticoid Programming of the Fetus: How in utero Events May Contribute to Both PTSD Vulnerability and Systemic Effects: Jonathan Seckl.

26. Towards an Animal Model of PTSD: Carsten T. Wotjak.

27. Establishing an Agenda for Translational Research in PTSD: Bruce McEwen

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