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When the first edition of this book published in 1994, the psychoimmunology of cancer was still emerging as a topic for serious scientific study. Now, less than ten years later, there is a huge academic literature about the relationships between psychological variables, the immun system and cancer growth, accompanied by a lively popular interest.
In this new edition leading specialists have provided broad critical reviews of the different aspects.
Part I, which presents the biological background, will be of particular interest to those with technical knowledge of the relevant laboratory based disciplines. It covers mechanisms mediating the effects of psychological status in the immune system, and anti-cancer mechanisms involving the immune system. Part II is clinically oriented, and accessible to a wide audience. Whether psychotherapeutic interventions can help patients live longer, as well as coping better, is obviously the key question and several contributors considern the clinical evidence for this. A new speculative chapter on the spiritual context of immunity and cancer has also been added.
The psychoimmunology of cancer involves many complex issues, understanding of which remains far from complete. However, the contributors, besides reviewing the current state of knowledge and the implications for cancer patients, offer predictions for the future and ideas about furhter research.
Preface, J. Barraclough C.E. Lewis R. O'Brien
Part I: Psychology, immunity and cancer: the biological links
1. Psychoimmunology today: mechanisms mediating the effects of psychological status on the immune system, Denise L. Bellinger, Srinivasan ThyagaRajan, Dianne Lorton, Kelley S. Madden, Lily Tran, David L. Felten
2. Anti-cancer mechanisms involving the immune system, P.W. Szlosarek, A. Dalgliesh
Part II: The clinical context: studies and speculations on human cancer
3. The role of psychological factors in cancer onset and progression: A critical appraisal, James L. Levenson, Kathy McDonald
4. Psychospiritual healing and the immune system in cancer, Roger J. Booth
5. Can psychosocial interventions extend survival? A critical evaluation of clinical trials of group and individual therapies, Karin Calde, Catherine Classen, David Spiegel
6. Psychological factors and cancer progression: involvement of neuroimmune pathways and future directions for laboratory research, Bert Garssen, Karl Goodkin
7. Psychological factors and cancer progression: involvement of behavioural pathways, Jennifer Anderson, Leslie G. Walker
8. The state of the art: clinical implications for cancer patients, and directions for future research, Alastair J. Cunningham