Psychopathology in the Genome and Neuroscience Era

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The fascinating Psychopathology in the Genome and Neuroscience Era brings together selected topics in psychiatric genetics, epidemiology and prevention, and neuroscience and education. This key reference integrates this information across the fields of genetics, epidemiology, and neuroscience to arrive at an understanding of where recent advances in genetics and neuroscience ? advances that promise to enhance our understanding of human behavior and psychopathology ? are likely to influence psychopathology ...

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Overview

The fascinating Psychopathology in the Genome and Neuroscience Era brings together selected topics in psychiatric genetics, epidemiology and prevention, and neuroscience and education. This key reference integrates this information across the fields of genetics, epidemiology, and neuroscience to arrive at an understanding of where recent advances in genetics and neuroscience — advances that promise to enhance our understanding of human behavior and psychopathology — are likely to influence psychopathology research and education in the near future.

How will the field of psychopathology incorporate the coming avalanche of information generated by these recent advances? The answer will influence not only how mental health professionals diagnose and treat patients but also how the next generation of professionals is trained.

Chapters in this exciting compilation are based on individual talks by 20 international experts at the conceptual forefront of their respective fields given at the March 2003 American Psychopathological Association annual meeting. Organized into four main sections — the future of psychiatric genetics, diagnosis and prevention of psychiatric disorders, neurobiology and psychiatric disorders, and the future of psychiatric education — Psychopathology in the Genome and Neuroscience Era focuses on a broad range of topics: • The importance of a conceptual shift from identifying major genes for mental disorders to gaining an understanding of the role of which genes in which contexts, both biological and environmental, confer susceptibility to or protection from mental disorders or components thereof• Historical perspective of gene susceptibility to mental disorders, with the same possibilities for use and misuse of genotype data as now exist for significantly heritable traits such as intelligence, and for borderline traits such as criminal behavior and alcoholism• Reconceptualization of medicine and medical diagnoses to include molecular genetic components, including the importance of cell loss and neurogenesis in mood disorders• Major phenotypic problems inherent in all attempts to measure psychopathology, starting with how to achieve reliability, and how to advance from reliability to validity in future revisions of DSM and ICD classifications• Brain structural abnormalities in mood disorders; physiological cell death and whether or not this natural phenomenon can be converted into a pathological process, including the importance of cell loss and neurogenesis in mood disorders• The influence of scientific advances, workforce issues, and educational trends on psychiatric training

Psychopathology in the Genome and Neuroscience Era is a must-read reference work for anyone — practitioners, residents, and students alike — interested in the future of psychiatric genetics, epidemiology, and education.

American Psychiatric Publishing

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Editorial Reviews

Doody's Review Service
Reviewer: Michael Joel Schrift, D.O., M.A.(University of Illinois at Chicago College of Medicine)
Description: This is an interesting new book covering the recent neuroscientific and genetic aspects of psychopathology. Advances in psychiatry have been hampered by not being able to establish brain-behavior correlates of phenomenology. Gall attempted this with phrenology, which of course fell in to disrepute. Psychiatry, with the rapid developments in cognitive neuroscience, molecular genetics and structural, functional, and neurochemical brain imaging, is now poised to elucidate these relationships between phenomenology/psychopathology and brain function, which will lead to significant advances in the understanding of mental illness and in psychiatric treatment. This book, which was developed from the March 2003 meeting of the American Psychopathological Association, brings together experts on psychiatric genetics, neuroscience, epidemiology, and education, is representative of the current state of knowledge, and lays out future directions for research. Written and edited by internationally recognized clinician-scientists in the field, the book is a welcome addition to the psychiatric literature.
Purpose: The purpose is to present, for practicing psychiatrists, a readable and accessible book documenting the latest findings in psychopathology and proposing ideas for the future of psychopathological research and training.
Audience: The intended audience includes clinical and academic psychiatrists, psychiatric residents, and researchers of ADHD, schizophrenia, Alzheimer disease, mood disorders, psychiatric genetics, and phenomenology.
Features: The book is divided into four parts containing 12 chapters and an index. Topics covered include genetics of mental disorders and of human behavior, genetics of ADHD and autism, late-onset Alzheimer Disease and genetics, problems with the current phenotypes in psychiatry, validity issues of the proposed DSM-V/ICD-11 revisions, new issues in prevention in light of the human genome, neuroscientific issues in regards to brain imaging in mood disorders, apoptosis and synaptogenesis, neurogenesis and psychopathology, and future needs for psychiatric training. Each chapter ends with relevant and contemporary citations of the literature.
Assessment: This is an excellent new book covering the present and future research perspectives on the neuroscience of psychopathology. This book will help practicing psychiatrists to keep abreast of this rapidly changing field. No psychiatrist should be left behind!

3 Stars from Doody
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Product Details

  • ISBN-13: 9781585622429
  • Publisher: American Psychiatric Publishing, Incorporated
  • Publication date: 10/28/2005
  • Pages: 256
  • Product dimensions: 6.00 (w) x 9.00 (h) x 0.65 (d)

Meet the Author

Charles F. Zorumski, M.D., is Samuel B. Guze Professor and Head of Psychiatry at Washington University School of Medicine in St. Louis, Missouri.

Eugene H. Rubin, M.D., Ph.D., is Professor in the Department of Psychiatry and Vice Chair for Education at Washington University School of Medicine in St. Louis, Missouri.

American Psychiatric Publishing

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Table of Contents

Part 1: The Future of Psychiatric Genetics. Bridging genetics and epidemiology of mental disorders. New genes for human behavior in historical perspective. Redefining early-onset disorders for genetic studies: attention-deficit/hyperactivity disorder and autism. Genetic risk factors for late-onset Alzheimer's disease. Part 2: Diagnosis and Prevention of Psychiatric Disorders. Are there phenotype problems? Advancing from reliability to validity: the challenge for the DSM-V/ICD-11 revisions. Prospects for prevention of mental disorders in the era of genomic medicine. Part 3: Neurobiology and Psychiatric Disorders. Brain structural abnormalities in mood disorders. Neuroapoptosis during synaptogenesis: a final common path to neurodevelopmental disturbances. Neurobiology, neurogenesis, and the pathology of psychopathology. Part 4: The Future of Psychiatric Education. Influence of scientific advances, workforce issues, and educational trends on psychiatric training. Crisis in American psychiatric education: an argument for the inclusion of research training for all psychiatric residents. Index.

American Psychiatric Publishing

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