Psychopharmacology and Women: Sex, Gender, and Hormones

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Psychopharmacology and Women: Sex, Gender, and Hormones brings together in one volume much of the information currently available on sex-related factors in psychopharmacoly. Chapters by recognized leaders in the field cover topics such as basic pharmacokinetic mechanisms of psychotropics in women, associations among endogenous hormones and neurotransmitters, interactions of psychotropics with exogenous sex steroid hormones, and psychopharmacological considerations relating to the menstrual cycle, pregnancy and ...
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Overview

Psychopharmacology and Women: Sex, Gender, and Hormones brings together in one volume much of the information currently available on sex-related factors in psychopharmacoly. Chapters by recognized leaders in the field cover topics such as basic pharmacokinetic mechanisms of psychotropics in women, associations among endogenous hormones and neurotransmitters, interactions of psychotropics with exogenous sex steroid hormones, and psychopharmacological considerations relating to the menstrual cycle, pregnancy and lactation, and menopause.

The book contains black-and-white illustrations.

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Editorial Reviews

Doody's Review Service
Reviewer: Katherine A. Tracy, MD, PhD (Rush University Medical Center)
Description: This a long-needed book examining much of the literature on gender-related factors in psychopharmacology, focusing almost entirely on women.
Purpose: Because research and clinical practice have often neglected sex differences in psychopharmacology, the purpose is to amass much of the available literature addressing this issue. Various experts in the field contribute toward fulfilling this objective. The editors subdivide this expansive topic into four sections examining psychopharmacology and the following: (1) gender differences; (2) life-cycle related changes, including the menstrual cycle, the puerperium, and the menopause; (3) psychopathology; and (4) considerations for clinical practice and future research.
Audience: Clinicians, medical educators, medical students, and researchers with interests in psychopharmacology and psychopathology should find this volume useful. Obstetricians and gynecologists should also benefit from the material reviewed.
Features: There are sufficient tables and figures and an extensive compilation of references at the end of the book. A few of the chapters have useful appendixes with topic specific references. The table of contents and index are adequate. A glossary is also included.
Assessment: This is a comprehensive volume reviewing much of the literature on issues important in the psychopharmacology of women. It brings together in one book diverse topics such as basic pharmacology, neuroanatomy, reproductive endocrinology, menstrual-related changes through the life cycle, and various psychopathologies. The authors make recommendations useful to the clinician in the treatment of women, and they suggest research directions important for enhancing the understanding of the use of psychotropic medications in women.
Katherine A. Tracy
This a long-needed book examining much of the literature on gender-related factors in psychopharmacology, focusing almost entirely on women. Because research and clinical practice have often neglected sex differences in psychopharmacology, the purpose is to amass much of the available literature addressing this issue. Various experts in the field contribute toward fulfilling this objective. The editors subdivide this expansive topic into four sections examining psychopharmacology and the following: (1) gender differences; (2) life-cycle related changes, including the menstrual cycle, the puerperium, and the menopause; (3) psychopathology; and (4) considerations for clinical practice and future research. Clinicians, medical educators, medical students, and researchers with interests in psychopharmacology and psychopathology should find this volume useful. Obstetricians and gynecologists should also benefit from the material reviewed. There are sufficient tables and figures and an extensive compilation of references at the end of the book. A few of the chapters have useful appendixes with topic specific references. The table of contents and index are adequate. A glossary is also included. This is a comprehensive volume reviewing much of the literature on issues important in the psychopharmacology of women. It brings together in one book diverse topics such as basic pharmacology, neuroanatomy, reproductive endocrinology, menstrual-related changes through the life cycle, and various psychopathologies. The authors make recommendations useful to the clinician in the treatment of women, and they suggest research directions important for enhancing the understanding of the use ofpsychotropic medications in women.
Booknews
The neglect of drug researchers to consider sex differences in their studies has become a major controversy in all medical fields including psychopharmacology. The 26 contributors to this collection address some of the concerns surrounding the basic pharmacokinetic mechanisms of psychotropics in women, including hormonal factors and neurotransmitters. Several discussions focus on women in the stages of the reproductive life, and also on how sex differences may affect manifestations of schizophrenia or anxiety disorders. The authors point to where research lags behind need, suggesting innovative strategies for testing that take into account ovulatory factors and more political maneuvers to promote gender sensitive research. Annotation c. Book News, Inc., Portland, OR (booknews.com)

3 Stars from Doody
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Product Details

  • ISBN-13: 9780880485456
  • Publisher: American Psychiatric Publishing, Inc.
  • Publication date: 6/1/1996
  • Edition number: 1
  • Pages: 599
  • Product dimensions: 6.37 (w) x 9.30 (h) x 1.54 (d)

Table of Contents

Contributors
Preface
Ch. 1 Gender-Sensitive Psychopharmacology: An Overview 3
Ch. 2 Sex Differences in Pharmacokinetics of Psychotropic Medications, Part I: Physiological Basis for Effects 11
Ch. 3 Sex Differences in Pharmacokinetics of Psychotropic Medications, Part II: Effects on Selected Psychotropics 43
Ch. 4 Sex Differences in Brain Morphology and Pharmacodynamics 73
Ch. 5 Association Among Ovarian Hormones, Other Hormones, Emotional Disorders, and Neurotransmitters 85
Ch. 6 Molecular Approaches to Sex Differences in Brain Functions, Including Motivation and Libido 107
Ch. 7 Gender and Ethnic Differences in the Pharmacogenetics of Psychotropics 121
Ch. 8 Nonpregnant Reproductive-Age Women, Part I: The Menstrual Cycle and Psychopharmacology 139
Ch. 9 Nonpregnant Reproductive-Age Women, Part II: Exogenous Sex Steroid Hormones and Psychopharmacology 171
Ch. 10 Psychopharmacological Treatment During Pregnancy and Lactation 191
Ch. 11 Menopause, Early Aging, and Elderly Women 225
Ch. 12 Sex and Treatment of Depressions: When Does It Matter? 241
Ch. 13 Anxiety Disorders in Women and Their Pharmacological Treatment 261
Ch. 14 Sex Differences in Schizophrenia 287
Ch. 15 Women and Substance Use Disorders 299
Ch. 16 Sexual Side Effects of Psychotropic Drugs in Women and Men 323
Ch. 17 Psychopharmacological Drug Testing in Women 371
Ch. 18 Individual Variation in Biological Rhythms: Accurate Measurement of Preovulatory LH Surge and Menstrual Cycle Phase 393
Ch. 19 Future Research Directions: Methodological Considerations for Advancing Gender-Sensitive Pharmacology 415
Glossary 431
References 449
Index 565
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