Purines in Cellular Signaling: Targets for New Drugs

Purines in Cellular Signaling: Targets for New Drugs

by Kenneth A. Jacobson, John W. Daly, Vincent Manganiello
     
 

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Research on purine derivatives as potent and selective modulators of physiologic functions has moved to center stage. This volume covers the biology and chemistry of purines and of their receptors broadly under these section headings: - Adenosine Receptors and Effector Systems - Adenine Nucleotide Receptors and Effector Systems - Phosphodiesterase Enzymes and

Overview

Research on purine derivatives as potent and selective modulators of physiologic functions has moved to center stage. This volume covers the biology and chemistry of purines and of their receptors broadly under these section headings: - Adenosine Receptors and Effector Systems - Adenine Nucleotide Receptors and Effector Systems - Phosphodiesterase Enzymes and Inhibitors The presentations focus on the potential development of clinically useful drugs and powerful agents that activate or block purinergic receptors or that inhibit phosphodiesterases. Xanthines (caffeine and theophylline) represent one class of such agents. This volume is for pharmacologists, biochemists, and medical chemists in research labs of universities, gov- ernment, and the pharmaceutical industry.

Editorial Reviews

Booknews
Covers the biology and chemistry of purines and of their receptors in three sections, covering adenosine receptors and effector systems; adenine nucleotide receptors and effector systems; and phosphodiesterase enzymes and inhibitors. The presentations focus on the potential development of clinically useful drugs and powerful agents that activate or block purinergic receptors or that inhibit phosphodiesterases. Annotation c. Book News, Inc., Portland, OR (booknews.com)

Product Details

ISBN-13:
9780387972442
Publisher:
Springer New York
Publication date:
04/28/1990
Edition description:
1990
Pages:
448
Product dimensions:
0.00(w) x 0.00(h) x (d)

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