Quantitative Molecular Pharmacology and Informatics in Drug Discovery / Edition 1

Hardcover (Print)
Buy New
Buy New from BN.com
$281.99
Used and New from Other Sellers
Used and New from Other Sellers
from $270.75
Usually ships in 1-2 business days
(Save 21%)
Other sellers (Hardcover)
  • All (5) from $270.75   
  • New (3) from $291.05   
  • Used (2) from $270.75   

Overview

Quantitative Molecular Pharmacology and Informatics in Drug Discovery Michael Lutz, Section Head, Cheminformatics Group and Terry Kenakin, Principal Research Scientist, Glaxo Wellcome Research and Development, Research Triangle Park, NC, USA Quantitative Molecular Pharmacology and Informatics in Drug Discovery combines pharmacology, genetics and statistics to provide a complete guide to the modern drug discovery process. The book discusses the pharmacology of drug testing and provides a detailed description of the statistical methods used to analyze the resulting data. Application of genetic and genomic tools for identification of biological targets is reviewed in the context of drug discovery projects. Covering both the theoretical principles upon which the techniques are based and the practicalities of drug discovery, this informative guide.
* outlines in step-by-step detail the advantages and disadvantages of each technology and approach and links these to the type of chemical target being sought after in the drug discovery process; and,
* provides excellent demonstrations of how to use powerful pharmacological and statistical tools to optimize high-throughput screening assays.
Written by two internationally known and well-regarded experts, this book is an essential reference for research and development scientists working in the pharmaceutical and biotechnology industries. It will also be useful for postgraduates studying pharmacology and applied statistics.

Disc. affinity & efficacy measurements, assay design, mathe- matical & statistical considerations, experimental design.

Read More Show Less

Editorial Reviews

From the Publisher
"...a timely and important book..." "I recommend this book to pharmaceutical company statisticians..."
—Biometrics, September 2000

"...covers a tremendous amount of ground....I recommend this book to pharmaceutical statisticians..."
—Technometrics, 2000

Read More Show Less

Product Details

  • ISBN-13: 9780471988618
  • Publisher: Wiley
  • Publication date: 1/11/2000
  • Edition number: 1
  • Pages: 428
  • Product dimensions: 6.22 (w) x 9.45 (h) x 1.12 (d)

Table of Contents

Drug Discovery.

Measurement of Drug Affinity.

Efficacy.

Pharmacological Assays Used in Screening for Therapeutic Ligands.

Finding the Optimal Assay Format for the Chemical Target.

Mathematical and Statistical Framework for Problems in Drug Discovery.

Statistical Methods for Target Identification and Validation.

Experimental Design.

Analysis and Interpretation of Data.

Index.

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)