Radiotherapy for Non-Malignant Disorders / Edition 1

by Michael Heinrich Seegenschmiedt, L.W. Brady, Hans-Bruno Makoski, H.-P. Heilmann, Klaus-Rüdiger Trott

Overview

Non-malignant, or "benign", diseases can be successfully treated using ionizing rad- tion technologies. It was first proposed in 1898 by Sokoloff, who reported the analgesic effects of radiotherapy for painful rheumatoid arthritis. Since then, the use of these techniques for painful muscle-skeletal diseases has gained acceptance particularly in Europe but is still carried out actively in the United States. Non-malignant diseases that are amenable to radiotherapy can be classified as inflammatory, degenerative, hype- roliferative, functional, or other disorders. However, the topographic and morphologic considerations are more relevant. Even though radiation therapy for "benign" diseases has not been pursued actively since the 1950s, more recent interest has dictated that it can be a very effective treatment modality. The use of radiotherapy can be justified for invasive and aggressive growth such as that seen with desmoids, for cosmetic d- figurations and functional loss as seen with keloids or endocrine orbitopathy, or for life-threatening complications such as hepatic hemangiomas or juvenile angiofibromas that occur in children or adolescents. Many of the non-malignant diseases can have a major and lasting effect on quality of life by causing pain or other serious symptoms, particularly when other methods of treatment are unavailable, have failed, or may induce more side effects. It is not generally the first choice of therapy in these non-malignant diseases, but it is acceptable as defined. The book edited by Seegenschmiedt et al.

Product Details

ISBN-13:	9783540625506
Publisher:	Springer Berlin Heidelberg
Publication date:	11/29/2007
Series:	Medical Radiology
Edition description:	2008
Pages:	748
Product dimensions:	7.99(w) x 10.87(h) x 0.06(d)

Table of Contents

General Background.- Radiobiological Principles.- Side Effects and Long-Term Risks from Radiotherapy of Non-malignant Diseases.- Risk Assessment and Carcinogenesis Modelling.- Radiophysical Principles.- Clinical Principles.- Irradiation of Non-malignant Diseases: An International Survey.- Patterns-of-Care Study for Non-malignant Diseases in Germany.- Skin and Soft Tissue Disorders.- Non-malignant Skin Disorders: Tumors, Hyperplasia, Dermatoses.- Morbus Dupuytren/Morbus Ledderhose.- Pronie’s Disease.- Keloids and Hypertrophie Scars.- Aggressive Fibromatosis/Desmoid Tumors.- Bone and Joint Disorders.- Orthopaedic Examination, Tests and Clinical Scores.- Rotator Cuff Syndrome (RCS).- Humeral Epicondylopathia (HEP), Lateral and Medial Humeral Epicondylitis.- Calcaneodynia: Plantar and Dorsal Heel Spur/Heel Spur Syndrome.- Degenerative Joint Disease Activated Osteoarthrosis Deformans: Hip, Knee, Shoulder and Other Joints.- Heterotopic Ossifications: General Survey for All Sites.- Heterotopic Ossification Prophylaxis - The Hip.- Heterotopic Ossifications after Head and Spinal Cord Injuries (HSCI).- Pigmented Villonodular Synovitis (PVNS).- Langerhans? Cell Histiocytosis (LCH).- Vertebral Hemangioma (VH).- Aneurysmal Bone Cyst (ABC).- Vascular Disorders.- Giant Hemangioma/Kasabach-Merritt Syndrome.- Eye Disorders.- Graves’ Orbitopathy.- Pseudotumor Orbitae.- Pterygium.- Hemangiomas and Vascular Tumors of the Eye.- Local and Systemic Inflammatory Disorders.- Inflammatory Disorders: Furunculitis, Hidradenitis, Panaritium and Paronychia.- Lymphocutaneous Fistulas and Lymphoceles.- Local Rheumatoid Arthritis and Radiation Synovectomy.- Head and Neck.- Non-Malignant Disorders of the Head Region.- CNS and Brain.- Arterio-Venous Malformations.- Meningioma.- VestibularSchwannoma (Acoustic Neuroma).- Pituitary Adenoma.- Trigeminal Neuralgia.- Radiosurgical Treatment Options for Epileptic Disorders.- Where There is No Evidence: Registry for Rare Benign Diseases.

Editorial Reviews

Reviewer: Ann Pittier, MD (University of Washington Medical Center)
Description: This all-inclusive book addressing benign conditions that can be treated with radiation covers first principles for the radiobiology and physics associated with treatment and its delivery and then details the conditions, treatment options, and techniques of therapy.
Purpose: The purpose is to provide readers with current indications, rationale, and the technical "how to" for the treatment of benign conditions with radiotherapy. This book clearly meets those objectives in a clear, concise, and comprehensive manner.
Audience: According to the authors, the book is designed for practitioners and all medical specialists, particularly radiation oncologists, orthopedists, surgeons, and ophthalmologists. In addition, it will be an invaluable resource for residents in these fields.
Features: This book provides an evidence-based approach and comprehensive understanding of the roll of radiation in nonmalignant disorders and lays the framework for understanding the disease in the multidisciplinary setting. It addresses mechanism of action for treatment options and a consensus for treatment approaches. It further highlights the areas of weakness in terms of evidence, but supplants expert opinion when necessary. This book fills a much needed gap in the repertoire of books available in the radiation field. It pulls together an updated, evidence-based approach and addresses the historic background that leads to the current recommendations of treatment. Each section brings together an exhaustive literature review for clinicians to have at their fingertips. The authors include internationally renowned specialists at the top of their field and they provide valuable insight to students, residents, and clinicians in radiation oncology and specialists who routinely manage these difficult cases (including neurosurgeons, dermatologists, ophthalmologists, and podiatrists). This book broadens the scope of options for specialists and the radiation oncologists alike. Two broad sections covering principles and clinical applications constitute the framework of this book. The first section forms the foundation of knowledge for a thorough understanding behind radiotherapeutic management. The clinical section organized by system is relevant for treatment care. Each chapter is well organized and allows for quick reference by breaking down the sections into concepts. Color pictures, tables, and figures illustrate the main points and a bulleted summary ends each chapter.
Assessment: This is an important addition to the literature for radiation oncologists as well as for a broad range of specialists. This is an outstanding resource for residents and clinicians as it brings together an exhaustive fund of knowledge in an area neglected by our specialty. It broadens the scope of management for many diseases and guides management, from conservative to aggressive.

Doody's Review Service

From the reviews:

"This all-inclusive book addressing benign conditions that can be treated with radiation covers first principles for the radiobiology and physics associated with treatment and its delivery and then details the conditions, treatment options, and techniques of therapy. … the book is designed for practitioners and all medical specialists, particularly radiation oncologists, orthopedists, surgeons, and ophthalmologists. … an important addition to the literature for radiation oncologists as well as for a broad range of specialists. This is an outstanding resource for residents and clinicians … ." (Ann Pittier, Doody’s Review Service, May, 2008)

"The chapter in the textbook entitled Radiotherapy for Non-Malignant Disorders that covers the treatment of nonmalignant central nervous system (CNS) disorders by using ionizing radiation is a well-written, concise, and organized accounting of the current state of the art for physicians and residents in neurosurgery, neurology, neuro-oncology, medical physics, and radiation oncology. … is an excellent reference guide for any clinical member of the treatment team for these diseases." (American Journal of Neuroradiology, Vol. 29, November-December, 2008)

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