Recent Advances in Cellular and Molecular Aspects of Angiotensin Receptors

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Editorial Reviews

From the presentations at a December 1994 international symposium in Gainsville, Florida, 27 were chosen to provide a complete summary of the recent and current research into angiotensin receptors in the several independent systems of the body in which they are now known to be present. The topics include the regulation of the genes for the receptors, interactions between them and neurotransmitters and peptides, their distribution in various tissues, varieties, and atypical receptors. Annotation c. Book News, Inc., Portland, OR (
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Product Details

Table of Contents

1 Characterization of a cis-Regulatory Element and trans-Acting Protein That Regulates Transcription of the Angiotensin II Type 1A Receptor Gene 1
2 Human AT[subscript 1] Receptor Gene Regulation 11
3 Regulation of Gene Transcription of Angiotensin II Receptor Subtypes in the Heart 23
4 Sodium Induced Regulation of Angiotensin Receptor 1A and 1B in Rat Kidney 33
5 Characterization and Regulation of Angiotensin II Receptors in Rat Adipose Tissue: Angiotensin Receptors in Adipose Tissue 39
6 Changes in Angiotensin AT[subscript 1] Receptor Density during Hypertension in Fructose-Fed Rats 49
7 Cardiac Effects of AII: AT[subscript 1A] Receptor Signaling, Desensitization, and Internalization 59
8 AT[subscript 1]-Receptors and Cellular Actions of Angiotensin II in Neuronal Cultures of Stroke Prone-Spontaneously Hypertensive Rat Brain 71
9 Antisense Oligonucleotides for in Vivo Studies of Angiotensin Receptors 79
10 Interactions of Angiotensin II with Central Dopamine 93
11 Regulation of the Hypothalmic-Pituitary-Adrenal Axis and Vasopressin Secretion: Role of Angiotensin II 105
12 Relationship between the Drinking Response to Angiotensin II and Induction of fos in the Brain 113
13 Identification of AT[subscript 1] Receptors on Cultured Astocytes 121
14 Structure-Activity Relationship of the Agonist-Antagonist Transition on the Type I Angiotensin II Receptor; the Search for Inverse Agonists 131
15 Molecular Cloning and Expression of Angiotensin II Type 2 Receptor Gene 145
16 Molecular Cloning of the Human AT[subscript 2] Receptor 153
17 Molecular and Functional Characterization of Angiotensin II AT2 Receptor in Neuroblastoma N1E-115 Cells 167
18 Characterization of the AT[subscript 2] Receptor on Rat Ovarian Granulosa Cells 175
19 AT[subscript 2] Receptor Expression in Ovaries: A Review 183
20 Heterogeneity of Rat Angiotensin II AT[subscript 2] Receptor 189
21 Heterogeneity of Angiotensin Type 2 (AT[subscript 2]) Receptors 199
22 Angiotensin II Stimulates Protein Phosphatase 2A Activity in Cultured Neuronal Cells via Type 2 Receptors in a Pertussis Toxin Sensitive Fashion 209
23 Functional Aspects of Angiotensin Type 2 Receptor 217
24 Angiotensin Receptor Heterogeneity in the Dorsal Medulla Oblongata as Defined by Angiotensin-(1-7) 225
25 Atypical (Non-AT[subscript 1], Non-AT[subscript 2]) Angiotensin Receptors 237
26 Brain Angiotensin II and Related Receptors: New Developments 247
27 Receptors for (3-8) Angiotensin in Brain Cells: AngIV Binding in Brain Cells 253
Index 265
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