Recent Advances on the Pathogenesis and Management of Diabetes: Proceedings of the 9th Korea-Japan Symposium on Diabetes Mellitus

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Editorial Reviews

In these 75-plus presentations from the April 1997 symposium, doctors from Korean and Japanese universities and hospitals describe recent research advances related to diabetes mellitus in such areas as obesity and insulin resistance, etiology, clinic al diabetes, immunology, macroangiopathy, lipids and lipoproteins, insulin synthesis and secretion, treatment, insulin action, epidemiology, diabetes education, and complications. Annotation c. by Book News, Inc., Portland, Or.
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Product Details

  • ISBN-13: 9780444828569
  • Publisher: Elsevier Science
  • Publication date: 4/28/1998
  • Series: International Congress Series
  • Edition number: 1
  • Pages: 460

Table of Contents

President's Opening Address. Lectures. Plenary Lecture. Oxidative stress and diabetic vascular complications in Korea (S.H. Shinn). Luncheon Lecture. Artificial endocrine pancreas — past, present and future (M. Shichiri). Recent Advances in the Pathogenesis of Diabetes Mellitus. Approach to the pathogenesis of non-insulin-dependent diabetes mellitus using genetically engineered knockout animals (T. Kadowaki et al.). Diabetic angiopathy and oxygen free radicals (B.-W. Kim). Mutations of the IRS-1 gene and their impact on insulin resistance (E. Araki et al.). Cytokine and autoimmune diabetes (M.-S. Lee, N. Sarvetnick). New Therapeutic Approaches in Diabetes Mellitus. The efficacy of metformin monotherapy in patients with NIDDM in Korea (Y.B. Ahn, H.Y. Son). Aldose reductase inhibitor and its therapeutic potential in diabetic complications (N. Hotta et al.). Obesity/Insulin Resistance. Insulin resistance, visceral fat and hypertension (K. Tanigawa et al.). Improvement of ß-cell function with long-term treatment of acarbose or metformin in NIDDM (Y. Mori et al.). The correlation between insulin resistance and the visceral fat vs. skeletal muscle ratio (VMR) in middle-aged women (B.S. Cha et al.). The difference of SHBG concentration in patients with NIDDM (Y.J. Pyun et al.). Correlation between serum leptin level and abdominal fat distribution in Korean adults (S.-W. Lee, Y.-S. Choi, S.-J. Lee). An interview-based assessment of eating behavior in nonobese and obese subjects (M. Shintani et al.). Mononuclear cell manganese superoxide dismutase (Mn-SOD) activity in non-insulin-dependent diabetic patients (H.-C. Bae et al.). Etiology. Identification of glucokinase mutations in subjects with postrenal transplantation diabetes mellitus (H.C. Lee et al.). Insulin secretory defect as an early metabolic defect in offspring of NIDDM (Y.-S. Chung, K.-W. Lee, H.-M. Kim). Family history of diabetes and anti-GAD antibodies in nonobese NIDDM (Y. Yoshida et al.). Risk factor determination for pregnancy-induced impaired glucose tolerance (IGT) (N.H. Cho et al.). Peripheral blood mitochondrial DNA content can predict the development of diabetes (J.J. Koh et al.). Absence of a Gly40Ser mutation in the glucagon receptor genes of Japanese NIDDM and hypertension patients (N. Babaya et al.). The ß-adrenergic receptor gene polymorphism (Trp64Arg) in Korean NIDDM (H.R. Li et al.). Non-HLA genetic markers for Korean insulin-dependent diabetic patients (S. Lee et al.). Clinical Diabetes. C-peptide and clinical presentation follow-up study in newly onset diabetes of the young (H.S. Kim et al.). The patterns of clinical characteristics according to body weight and weight changes in Korean NIDDM patients (Y.S. Hong et al.). Characteristics of NIDDM patients with fasting hyperglycemia (K. Nojima et al.). Clinical and immunogenetic characteristics of the patients occurring diabetic ketoacidosis in Korea (H.S. Kim et al.). Anemia in nonuremic diabetic patients (Y.S. Yun et al.). Comparison of World Health Organization and National Diabetes Data Group criteria to detect abnormal glucose tolerance in Korean pregnant women (M.H. Kang, H.Y. Park, S.K. Lee). Immunology. HLA-DRB1/DQB1 genes and susceptibility to IDDM in Koreans (Y. Park et al.). Molecular cloning of new autoantigens reactive with prediabetic NOD sera (Y. Kang et al.). Increased prevalence of autoimmune diseases in IDDM patients (Y. Cho et al.). Expression of Fas in murine pancreatic ß cells and its significance (M.-S. Lee et al.). Islet-specific autoantibodies and HLA DRB/DQA/DQB polymorphism in Korean IDDM (J. Shin et al.). Measurements of anti-GAD Ab by EIA and RIA methods in Korean diabetic patients (C.H. Chung et al.). The combination of multiple autoantibodies to islet-specific antigens in Korean insulin-dependent diabetic patients (Y. Park et al.). Antibody to GAD and islet cell autoantibody in Korean diabetic patients.(J. Yoo et al.). Macroangiopathy. The GLN-ARG191 polymorphism of the human paraoxonase gene in Korean coronary artery disease patients with/without diabetes (Y. Cho et al.). Effect of insulin on gene expression and synthesis of collagen in aortic smooth muscle cells cultured in normal and high glucose (S.W. Ha et al.). Oxygen free radical induced impairment of endothelium dependent relaxation in diabetic rat aortas (J.-G. Kim, S.-W. Ha, B.-W. Kim). Blood pressure pattern of pregnancy complicated with impaired glucose tolerance (K.S. Oh et al.). Relationship between carotid artery plaque measured by ultrasound and cerebral infarction in patients with non-insulin-dependent diabetes mellitus (NIDDM) (T.S. Park et al.). The cerebral hemodynamic changes measured by transcranial Doppler in normotensive, hypertensive and diabetic patients (J.H. Nam et al.). Hemodynamic study of the feet of diabetic patients using a portable Doppler machine (H. Moon et al.). A study of the differentiated analysis of plethysmography in diabetes mellitus (H. Ueda et al.). Effect of high glucose on function of cultured rabbit vascular endothelial cells (S.M. Son et al.). The activation of PKC is involved in Ox-LDL-induced macrophage growth (T.Matsumura et al.). Lipoprotein(a) level and vascular complications in NIDDM (J.Y. Kim et al.). Lipids and Lipoproteins. Acute effect of insulin on triglycerides clearance in nondiabetic normolipidemic female subjects (T. Goto et al.). Plasma plant sterol levels and morphological markers of intestine in diabetes (H. Hidaka et al.). Insulin Synthesis and Secretion. Analysis of &Agr;-cell function in spontaneous diabetic NSY mice (Y. Hamada et al.). Leptin directly stimulates basal insulin release from pancreatic ß cells (S. Okuya et al.). Comparison of GLUT2 expression and glucokinase activity between D11 and its parent RINm5F cells (T.-W. Yoon). Treatment. Effects of troglitazone on hyperglycemia-induced insulin resistance (M.-K. Lee et al.). Effects of long-term administration of an ß-glucosidase inhibitor on the development of macroangiopathy in OLETF rats (Y. Mori et al.). Insulin Action. Effect of pertussis and cholera toxins on insulin receptor recycling in isolated fat cells of rats (S.-A. Chang et al.). Subcellular distribution and functional changes of GTP-binding proteins (G-proteins) in adipocytes of streptozotocin-induced insulin-dependent diabetic rats and changes in the amount and function of G-protein in adipocytes from type II diabetic patients (B.Y. Cha et al.). Fibroblast PC-1 mRNA content and insulin sensitivity in Korean NIDDM patients (H.-M. Kim et al.). Epidemiology. Study on proinsulin levels in IGT and normal groups. Report 1: correlation between development of NIDDM and proinsulin levels (C. Ito, Y. Shibata). Diabetes Education. Self-assessment of the capability for patient education in diabetes

(T. Asahina et al.). Dietary habits in Korean type II diabetic patients (S. Park, E.K. Choi, S.B. Choi). Medical optical memory card system to construct a medical information network for diabetic patients (M. Nomura et al.). Nutrition knowledge and dietary management of Korean diabetics living in the Suwon area (H.R. Park et al.). Implementation of a practice guideline to diabetes management (K. Nakata et al.). The relationship between plasma glucose and insulin secretion on 75-g OGTT (S. Masashi et al.). Complications. Ultrastructure of neuromuscular junction in Vacor-induced diabetic rats (T.H. Lee, J.S. Ahn, M.C. Lee). Significance of the sympathetic skin response (SSR) and F wave in IDDM with neuropathy (S. Takayama et al.). Analysis of diabetic neuropathy symptoms and pathophysiology (K. Takekawa, E. Yamato, T. Hata). Cognition disorder in elderly diabetic patients is related to glycemic control (Y. Goriya et al.). Power spectral analysis of heart rate in microalbuminuric diabetic patients (J. Kim et al.). Glycemic threshold for lowering urinary albumin excretion (K. Iwashima et al.).Intrarenal resistive index (RI) and the extracellular matrix in NIDDM patients with nephropathy (H. Hiroyuki, U. Kenzo, Y. Itaru).The effect of PGE1 on symptom and vascular cell damage in diabetic patients with limb numbness (Y. Kawabata et al.). Intra-arterial infusion of prostaglandin analogue in the management of diabetic foot gangrene (S.-N. Choi et al.). Optimal dose evaluation of mexiletine in patients with diabetic painful neuropathy (K. Matsuoka et al.). Preventive effect of cilostazol on the reduced sciatic nerve blood flow in the streptozotocin-induced diabetic rat (Y.D. Song et al.). Erythrocyte aldose reductase level and the progression of diabetic retinopathy (Y. Takahashi et al.). Index of Authors. Keyword Index.

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