Reconceiving the Gene: Seymour Benzer's Adventures in Phage Genetics

Reconceiving the Gene: Seymour Benzer's Adventures in Phage Genetics

by Frederic Lawrence Holmes
     
 

ISBN-10: 0300110782

ISBN-13: 9780300110784

Pub. Date: 06/21/2006

Publisher: Yale University Press

This book relates how, between 1954 and 1961, the biologist Seymour Benzer mapped the fine structure of the rII region of the genome of the bacterial virus known as phage T4. Benzer’s accomplishments are widely recognized as a tipping point in mid-twentieth-century molecular biology when the nature of the gene was recast in molecular terms. More often

…  See more details below

Overview

This book relates how, between 1954 and 1961, the biologist Seymour Benzer mapped the fine structure of the rII region of the genome of the bacterial virus known as phage T4. Benzer’s accomplishments are widely recognized as a tipping point in mid-twentieth-century molecular biology when the nature of the gene was recast in molecular terms. More often than any other individual, he is considered to have led geneticists from the classical gene into the molecular age.
 
Drawing on Benzer’s remarkably complete record of his experiments, his correspondence, and published sources, this book reconstructs how the former physicist initiated his work in phage biology and achieved his landmark investigation. The account of Benzer’s creativity as a researcher is a fascinating story that also reveals intriguing aspects common to the scientific enterprise.

Product Details

ISBN-13:
9780300110784
Publisher:
Yale University Press
Publication date:
06/21/2006
Edition description:
New Edition
Pages:
352
Product dimensions:
6.13(w) x 9.25(h) x 1.06(d)

Table of Contents

Contents

Preface....................vii
Acknowledgments....................xi
Author's Note....................xiii
Chapter One. Classical Mendelian Genetics....................1
Chapter Two. Genetics and the Phage Biologists....................29
Chapter Three. The Physicist Becomes a Phage Biologist....................75
Chapter Four. To Paris and Back....................122
Chapter Five. Teaching and Research at Purdue....................146
Chapter Six. Entering the rII Region....................179
Chapter Seven. Crossing into the Fine Structure....................222
Chapter Eight. Is Gene a Dirty Word?....................269
Chapter Nine. The Survival of the "Gene"....................299
Notes....................303
Index....................331

Customer Reviews

Average Review:

Write a Review

and post it to your social network

     

Most Helpful Customer Reviews

See all customer reviews >