Resistance to Antineoplastic Drugs

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1989 Hardcover Very Good Ex-Library Cond Book 8vo-over 7?"-9?" tall 448 pgs. Usual library markings. Binding tight, pages clean. Chapter titles include: The multidrug resistant ... phenotype and its relationship to glutathione; mode of action of taxol and characterization of ultidrug-resistant cell line selected with taxol; tumor cell resistance to etoposide (VP-16); malignant cell resistance to bleomycin-group antibiotics; drug resistance to cytosine arabinoside; and much more. Read more Show Less

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Boca Raton 1989 Hardcover Very Good Ex-Library Cond Book 4to-over 9?"-12" tall 448 pgs. CHAPTER TITLES: historical aspects pertaining to the problem of tumor resistance to ... chemotherapy; a molecualr basis for multidrug resistance in human cancer; multidrug (pleiotropic) resistance in the human sarcoma cell line, MES-SA; the multidrug resistant phenotype and its relationship to glutathione; structure-activity relationship of compounds that restore sensitivity to doxorubicin in drug-resistant P388 cells; modulation of acquired anthracycline resistance by calmodulin inhibitors; mode of action of taxol and characterization of multidrug-resistant cell line selected with taxol; the role of the cell surface membrane in Adriamycin resistance; vinca alkaloid pharmacology and resistance; the selective transfer of drug-resistant genes in malignant cells; tumor cell resistance to etoposide (VP-16)--a review; resistance to teniposide and etoposide; drug resistance, DNA repair and growth factors; emerging evidence for co Read more Show Less

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Boca Raton 1989 Hardcover Very Good Ex-Library Cond Book 4to-over 9?"-12" tall 448 pgs. CHAPTER TITLES: historical aspects pertaining to the problem of tumor resistance to ... chemotherapy; a molecualr basis for multidrug resistance in human cancer; multidrug (pleiotropic) resistance in the human sarcoma cell line, MES-SA; the multidrug resistant phenotype and its relationship to glutathione; structure-activity relationship of compounds that restore sensitivity to doxorubicin in drug-resistant P388 cells; modulation of acquired anthracycline resistance by calmodulin inhibitors; mode of action of taxol and characterization of multidrug-resistant cell line selected with taxol; the role of the cell surface membrane in Adriamycin resistance; vinca alkaloid pharmacology and resistance; the selective transfer of drug-resistant genes in malignant cells; tumor cell resistance to etoposide (VP-16)--a review; resistance to teniposide and etoposide; drug resistance, DNA repair and growth factors; emerging evidence for co Read more Show Less

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Articles summarize selected developments in current research on different modes of resistance to drugs employed in in vitro experiments involving neoplastic cells. Topics covered include: multi drug resistance in human cancer and in the human sarcoma cell line, modulation of acquired anthracycline resistance by calmodulin inhibitors, cell surface membrane in adriamycin resistance, tumor cell resistance to etoposide (VP-16), resistance to teniposide and etoposide, and drug resistance to cyotsine arabinoside and anti estrogen therapy. Annotation c. Book News, Inc., Portland, OR (booknews.com)
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Product Details

  • ISBN-13: 9780849348006
  • Publisher: CRC Press
  • Publication date: 1/1/1989
  • Pages: 464

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