Respiratory-Circulatory Interactions in Health and Disease

Overview

This book describes the basic, pathophysiologic, and clinical importance of the reciprocal relationships and interactions between the respiratory and cardiovascular systems, examining mechanical responses caused by lung volume and thoracic pressure.
Emphasizes humoral and neurophysical interactions occurring in diseases that lead to cardiorespiratory failure.
Covering pulmonary mechanics, respiratory muscle function, exercise physiology, and ...

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Overview

This book describes the basic, pathophysiologic, and clinical importance of the reciprocal relationships and interactions between the respiratory and cardiovascular systems, examining mechanical responses caused by lung volume and thoracic pressure.
Emphasizes humoral and neurophysical interactions occurring in diseases that lead to cardiorespiratory failure.
Covering pulmonary mechanics, respiratory muscle function, exercise physiology, and control of venous return and cardiac output, Respiratory-Circulatory Interactions in Health and Disease

  • focuses on mechanisms of heart failure in respiratory disease
  • details the central interactions in sudden infant death syndrome
  • considers the control of tissue metabolism, the development of the sympathetic nervous system, mathematical modeling, and image analysis as a tool for investigating cardiocirculatory function
  • examines the effects of muscle reflexes on respiration and circulation
  • analyzes systemic inflammatory response and chronic obstructive lung disease
  • discusses respiratory maneuvers to support failing circulation and ventilation
  • addresses current controversies surrounding the balloon-tipped catheter
  • debates using inhaled nitrous oxide to treat circulatory failure
  • and more!
    Supplying a rational basis for understanding the ways in which the cardiovascular and respiratory systems interact in normal and abnormal situations, Respiratory-Circulatory Interactions in Health and Disease is a blue-ribbon reference for cardiologists; pulmonologists; physiologists; intensivists; cardiothoracic surgeons; anesthesiologists; asthmatologists; health care practitioners interested in chest, pulmonary, and thoracic medicine; and medical school students in these disciplines.
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Editorial Reviews

Doody's Review Service
Reviewer: Roberto F. Machado, MD (Cleveland Clinic Foundation)
Description: This is a unique compilation of physiologic and pathophysiologic aspects of the complex interactions between the cardiovascular and respiratory systems. It is the second edition of a book that was originally published over a decade ago.
Purpose: The authors aim to describe the ways in which the cardiovascular and respiratory systems interact in health and disease. The book certainly achieves its goals, providing a much needed comprehensive review of the pathophysiology of heart-lung interactions.
Audience: Written by authorities in the field, the book is suited for readers with training or research interest in the areas of pulmonary, cardiology, and critical care medicine. People with substantial knowledge in these areas are likely to benefit the most from this book.
Features: The book is conveniently divided in three parts: basic physiology, pathophysiology, and clinical problems. Readers will find extensive information on the pathophysiology of heart and lung disorders ranging from basic concepts such as respiratory muscle mechanics to the molecular biology of cardiorespiratory failure. The section covering clinical problems stands out as a great resource for clinicians, providing tremendous insight on the pathophysiology of common disorders encountered in the practice of cardiology, pulmonary and critical care medicine.
Assessment: This new edition is most welcome. Although sometimes difficult to read, it is a comprehensive and updated compilation of all the important pathophysiologic and clinical aspects of cardiopulmonary problems.
Booknews
Treats mechanical and neurophysiological heart-lung interactions in the pathogenesis of clinical conditions, and touches on the humoral and molecular biological basis of disease leading to cardiorespiratory failure, especially the sepsis syndrome. Part I discusses basic physiological principles necessary for understanding cardiocirculatory interactions. This part includes description of pulmonary mechanics, respiratory muscle function, and cardiopulmonary interactions. Part II examines topics related to the generation of disease states, with material on neurophysiological interactions during sleep and the effects of systemic inflammatory response on cardiovascular function. Part III describes clinical conditions in terms of basic physiology and pathophysiology. There are chapters on the effects of heart failure, application of principles of heart-lung interactions in the critical care unit, and the use of inhaled NO to treat circulatory failure. Scharf is affiliated with Albert Einstein College of Medicine, and the Long Island Jewish Medical Center. Annotation c. Book News, Inc., Portland, OR (booknews.com)

4 Stars! from Doody
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Product Details

Table of Contents

Heart-Lung Interactions: An Overview
Steven M. Scharf, Michael R. Pinsky, and Sheldon Magder

BASIC PHYSIOLOGY

Respiratory Physiology

Lung and Chest Wall Mechanics: Basic Concepts
Joseph R. Rodarte
Respiratory Muscle Function and Blood Flow
Steven G. Kelsen

Cardiovascular Physiology

Right Ventricular Function and Ventricular Interdependence
William P. Santamore, Alfred A. Bove, and Louis J. Dell'Italia
Venous Return
Sheldon Magder and Steven M. Scharf
Models of Tissue Oxygen Uptake and Microcirculatory Blood Flow
Sorel Bosan and Keith R. Walley

Cardiopulmonary Physiology

The Sympathetic Nervous System of the Developing Mammal
Anthony L. Sica, Bruce W. Hundley, David A. Ruggiero, and Phyllis M. Gootman
Hemodynamic Effects of Ventilation and Ventilatory Maneuvers
Michael R. Pinsky
Homeostasis of Exercise Gas Exchange: Coupling of Pulmonary and Cardiovascular Function to Cellular Respiration During Exercise
Karlman Wasserman and William W. Stringer
Mechanical Heart-Pericardium-Lung Interactions
Masao Takata and James L. Robotham
Dynamic Volumetric Imaging-Based Assessment of the Intrathoracic Milieu
Eric A. Hoffman and Binh Q. Tran

PATHOPHYSIOLOGY

Cellular Mechanisms of Acute Hypoxic Pulmonary Vasoconstriction
J. T. Sylvester, James S. K. Sham, Larissa A. Shimoda, and Q. Liu
Pulmonary Edema: Formation and Reabsorption
Michael A. Matthay and Tsutomu Sakuma
Respiratory-Circulatory Interactions in Obstructive Sleep Apnea
Virend K. Somers, Krzysztof Narkiewicz, and Mikolaj Winnicki
Effects of Respiratory Muscle Afferent on the Breathing and the Afferent Hypothesis
Sheldon Magder
Neurohumoral Aspects of Respiratory-Cardiovascular Interactions
Sami I. Said
Pathophysiology of Pulmonary Hypertension
Jason X.-J. Yuan and Lewis J. Rubin
Effect of Systemic Inflammation on Cardiovascular Function
Bradley D. Freeman and Charles Natanson

CLINICAL PROBLEMS

Heart Failure

Control of Ventilation in Congestive Heart Failure
Harly Greenberg
Ventilatory Support in the Failing Heart
Steven M. Scharf

Sleep-Disordered Breathing

Blood Pressure Regulation and Sleep Apnea
Urs A. Leuenberger and Clifford W. Zwillich
Pathophysiological Interreactions Between Sleep Apnea and the Heart
T. Douglas Bradley, Geraldo Lorenzi-Filho, and John S. Floras
Cardiovascular Responses to Obstructive Apneas-Lessons from Animal Models
Steven M. Scharf, Ling Chen, Harly Greenberg, and Christopher P. O'Donnell
Sleep Apnea and Right Ventricular Function
Thomas E. Podszus, Christian Ole Feddersen, and Steven M. Scharf

Pulmonary Failure

Chronic Obstructive Pulmonary Disease
Samuel L. Krachman and Martin J. Tobin
Circulatory Effects of COPD
Bartolome R. Celli and Regina Frants

Critical Care

Invasive and Noninvasive Assessment of Cardiocirculatory Function: Balloon-Tipped Catheters and Echocardiography
Claude Perret, Francois Feihl, and Alain Cariou
Heart-Lung Interactions in Sepsis
Sheldon Magder
Nitric Oxide and Cardiopulmonary Failure in Sepsis
Rubin Cohen
Databases and Outcomes in Cardiopulmonary Care
Alan S. Multz and Corrado P. Marini
Mechanical Ventilation with PEEP
Henry E. Fessler
Cardiocirculatory Management in Acute Lung Injury and ARDS
René Gust and Daniel P. Schuster
Diagnostic Information from the Respiratory Variations in Central Hemodynamics Pressures
Sheldon Magder
Abdominal-Circulatory Interactions
Peter Goldberg
Inhaled Nitric Oxide and Acute Lung Injury
Didier Payen
Inhaled Nitric Oxide for Persistent Pulmonary Hypertension of the Newborn: Basis for Evolving Therapeutic Guidelines
Dennis Davidson

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