Respiratory Genetics

Hardcover (Print)
Used and New from Other Sellers
Used and New from Other Sellers
from $14.30
Usually ships in 1-2 business days
(Save 94%)
Other sellers (Hardcover)
  • All (6) from $14.30   
  • Used (6) from $14.30   
Close
Sort by
Page 1 of 1
Showing All
Note: Marketplace items are not eligible for any BN.com coupons and promotions
$14.30
Seller since 2006

Feedback rating:

(60435)

Condition:

New — never opened or used in original packaging.

Like New — packaging may have been opened. A "Like New" item is suitable to give as a gift.

Very Good — may have minor signs of wear on packaging but item works perfectly and has no damage.

Good — item is in good condition but packaging may have signs of shelf wear/aging or torn packaging. All specific defects should be noted in the Comments section associated with each item.

Acceptable — item is in working order but may show signs of wear such as scratches or torn packaging. All specific defects should be noted in the Comments section associated with each item.

Used — An item that has been opened and may show signs of wear. All specific defects should be noted in the Comments section associated with each item.

Refurbished — A used item that has been renewed or updated and verified to be in proper working condition. Not necessarily completed by the original manufacturer.

Good
Former Library book. Shows some signs of wear, and may have some markings on the inside. 100% Money Back Guarantee. Shipped to over one million happy customers. Your purchase ... benefits world literacy! Read more Show Less

Ships from: Mishawaka, IN

Usually ships in 1-2 business days

  • Canadian
  • International
  • Standard, 48 States
  • Standard (AK, HI)
  • Express, 48 States
  • Express (AK, HI)
$14.31
Seller since 2005

Feedback rating:

(10808)

Condition: Like New
2005-11-30 Hardcover 1 Fine 0340814322 LIKE NEW/UNREAD! ! ! Text is Clean and Unmarked! --Be Sure to Compare Seller Feedback and Ratings before Purchasing--Has three small black ... lines on bottom/exterior edge of pages. Tracking is not available for orders shipped outside of the United States. If you would like to track your domestic order please be sure to select the Priority/Expedited Shipping option. Read more Show Less

Ships from: McKeesport, PA

Usually ships in 1-2 business days

  • Canadian
  • International
  • Standard, 48 States
  • Standard (AK, HI)
  • Express, 48 States
  • Express (AK, HI)
$16.97
Seller since 2005

Feedback rating:

(10808)

Condition: Like New
2005-11-30 Hardcover 1 Fine 0340814322 LIKE NEW/UNREAD! ! ! Text is Clean and Unmarked! --Be Sure to Compare Seller Feedback and Ratings before Purchasing. Has a small black ... line on bottom/exterior edge of pages. Tracking is not available for orders shipped outside of the United States. If you would like to track your domestic order please be sure to select the Priority/Expedited Shipping option. Read more Show Less

Ships from: McKeesport, PA

Usually ships in 1-2 business days

  • Canadian
  • International
  • Standard, 48 States
  • Standard (AK, HI)
  • Express, 48 States
  • Express (AK, HI)
$22.00
Seller since 2006

Feedback rating:

(2992)

Condition: Like New
Like New 1st Edition. 2005. Hardcover. May have a remainder mark. Fine. No Dust Jacket.

Ships from: Chicago, IL

Usually ships in 1-2 business days

  • Canadian
  • International
  • Standard, 48 States
  • Standard (AK, HI)
  • Express, 48 States
  • Express (AK, HI)
$58.99
Seller since 2014

Feedback rating:

(56)

Condition: Good
Buy with Confidence. Excellent Customer Support. We ship from multiple US locations. No CD, DVD or Access Code Included.

Ships from: Fort Mill, SC

Usually ships in 1-2 business days

  • Standard, 48 States
$175.64
Seller since 2014

Feedback rating:

(298)

Condition: Like New
As new.

Ships from: Chatham, NJ

Usually ships in 1-2 business days

  • Canadian
  • International
  • Standard, 48 States
  • Standard (AK, HI)
  • Express, 48 States
  • Express (AK, HI)
Page 1 of 1
Showing All
Close
Sort by

Overview

There has been a recent explosion of knowledge in the field of respiratory genetics. This authoritative text brings together current knowledge in respiratory genetics in a single volume.

The book includes a comprehensive introductory section to provide guidance and aid understanding of key basic concepts in respiratory genetics, including statistical methods, sample collection, bioinformatics, and functional genomics. This is followed by a series of disease-specific chapters that review epidemiology, natural history, monogenic determinants, complex disease components, disease management, and likely future developments.

Respiratory Genetics is an essential reference for pulmonologists, translational researchers, and clinical geneticists, and the text will also be a useful library reference.

Read More Show Less

Editorial Reviews

Doody's Review Service
Reviewer: Joel C Seidman, MD (William Beaumont Hospitals)
Description: This is a unique compilation of basic and clinical sciences of respiratory medicine, edited from the perspective of the eclectic learning and experience of Edwin K. Silverman, MD, PhD, et al. In the introductory chapters, the authors reiterate information regarding traditional mammalian genetics, then explore the newer science of genomics including the basic molecular biology of heredity, the laboratory methodologies by which this biology has become understood, and the nomenclature and processes of documentation and archiving newly gathered information. The authors explain how the translation of peculiarities or constancies in genomics might predict or explain the pharmacobiology of respiratory medications now in use and/or lead to the "bio-logical" development of future pharmaceuticals. The latter part of the book is committed to explicit considerations of respiratory pathophysiologies with suspected or known heritable contributions: obstructive lung diseases (asthma, chronic obstructive pulmonary disease, and cystic fibrosis), interstitial lung diseases (idiopathic pulmonary fibrosis and sarcoidosis), and miscellaneous common conditions (bronchogenic carcinoma and certain respiratory infections) as well as miscellaneous rare disorders (primary pulmonary hypertension, congenital, metabolic, and neuromuscular disorders, surfactant disorders, lymphangioleiomyomatosis, and Hermansky-Pudlak syndrome).
Purpose: In aggregate, a comprehensive attempt is made to adopt observations of authorities from diverse scientific disciplines which do not necessarily regularly mingle even in the highest-regarded niches of academia. It is the editors' intent to combine current observations regarding clinical and molecular genetics, in general as well as with specific reference to selected bronchopulmonary pathophysiology, and current understanding in clinical respiratory medicine, wherein dysfunction and disease derive in part or wholly from perturbations in genomics or respiratory disorders of independent origin follow a natural history guided by heritable forces. Admittedly, such an endeavor would not permit "connection of all the dots," not just because the number and origin of contributors is so eclectic, but because their disciplines do not commonly overlap to a degree that any one individual might be even superficially knowledgeable across all the fields. Nonetheless, the science is far more elaborately explored perhaps than in any earlier attempt I have perused; in fact, I am unaware of any other book that has so comprehensively addressed the breadth of this challenge. This book successfully yokes basic science and clinical pulmonology in a manner uncommonly observed before.
Audience: The detailed handling of basic molecular and cellular respiratory biology makes the entire text suited for an experienced reader. However, if selectively perused, the genetic biology is clear, simplified, and concise enough to prove elaborative for clinicians. The simple approach provides enlightening information to well-informed practicing pulmonologists, and is sufficiently tame in its handling of the aforementioned diseases to amply inform readers who crave an understanding of the real-life events dictated by and evolving from the molecular biology and the disorders due to the genetic aberrations.
Features: The book focuses primarily upon the genetic molecular biology believed to underlie the evolution of common as well as rare bronchopulmonary diseases, and concurrently reviews the clinical features and natural history of these disorders. It appears to be novel as a comprehensive work linking basic science to a broad and seemingly all-inclusive array of clinical pulmonary medicine entities.
Assessment: This is an extremely useful book that helps to explain the genetic basis of common and rare pulmonary disorders. It is targeted at specialists in the field of pulmonary medicine and is well suited for fellows in training and all medical personnel interested in the role of genetics in common and uncommon diseases.
Read More Show Less

Product Details

  • ISBN-13: 9780340814321
  • Publisher: Taylor & Francis
  • Publication date: 9/30/2005
  • Series: A Hodder Arnold Publication Series
  • Pages: 496
  • Product dimensions: 10.90 (w) x 8.30 (h) x 1.30 (d)

Meet the Author

Edwin K Silverman, Assistant Professor of Medicine, Harvard Medical School, Boston, USA

Steven D Shapiro, Parker B. Francis Professor of Medicine, Harvard Medical School, Brigham & Womens Hospital, Boston, USA

David A Lomas, Professor, Respiratory Medicine Unit, University of Cambridge, UK

Scott T Weiss, Professor of Medicine, Harvard Medical School, Boston, USA

Read More Show Less

Table of Contents

Part 1: Key Concepts in Respiratory Genetics
Overview of human genetics
Phenotypes for Human Respiratory Genetics
Testing for association in genetic studies
Sample Collection and Genotyping for Human Respiratory Genetics
Molecular characterization of genetic variation: sample collection and processing in human respiratory genetics
Molecular characterization of genetic variation: genetic variation, genotyping, and sequencing
Bioinformatics: public databases and SNPs
Bioinformatics: genomics and proteomics in lung disease: microarrays and bioinformatics issues
Functional genomics: clinical functional genomics
Functional genomics: expression and purification of recombinant proteins
Functional genomics: functional characterization of a protein
Functional genomics: biophysical analysis of proteins and protein–protein interactions
Functional genomics: crystallography, nuclear magnetic resonance, and modeling
Functional genomics: functional analysis of mutant proteins in cells
Genomic physiology in animals
Pharmacogenetics
Part 2: Obstructive lung diseases
Asthma genetics
Chronic obstructive pulmonary disease
Cystic fibrosis
Part 3: Interstitial lung diseases
Idiopathic pulmonary fibrosis
Sarcoidosis
Part 4: Miscellaneous pulmonary conditions
Pulmonary hypertension
Genetics of lung cancer
Respiratory infections
Congenital, metabolic, and neuromuscular diseases
Other rare lung diseases: disorders of surfactant homeostasis
Other rare lung diseases: lymphangioleiomyomatosis
Other rare lung diseases: Hermansky–Pudlak Syndrome
Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)