Restorative Neurology of Spinal Cord Injury

Overview

Following injury or disease, neural circuitry can be altered to varying degrees leading to highly individualized characteristics that may or may not resemble original function. In addition, lost or partially damaged circuits and the effects of biological recovery processes coupled with learned compensatory strategies create a new neuroanatomy with capabilities that are often not functional or may interfere with daily life. To date, the majority of approaches used to treat neurological dysfunction have focused on ...

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Overview

Following injury or disease, neural circuitry can be altered to varying degrees leading to highly individualized characteristics that may or may not resemble original function. In addition, lost or partially damaged circuits and the effects of biological recovery processes coupled with learned compensatory strategies create a new neuroanatomy with capabilities that are often not functional or may interfere with daily life. To date, the majority of approaches used to treat neurological dysfunction have focused on the replacement of lost or damaged function, usually through the suppression of surviving neural activity and the application of mechanical assistive devices. Restorative Neurology of Spinal Cord Injury offers a different and novel approach.

Focusing on the spinal cord and its role in motor control, the book details the clinical and neurophysiological assessment process and methods developed throughout the past half century by basic and clinical scientists. Then, through the use of specialized clinical and neurophysiological testing methods, conduction and processing performed within the surviving neural circuitry is examined and characterized in detail. Based on the results of such assessment, treatment strategies, also described in this book, are applied to augment, rather than replace, the performance of surviving neural circuitry and improve the functional capacity of people who have experienced injury to their spinal cords.

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Editorial Reviews

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"Seabird Islands provides a solid first attempt at compiling available data in a sparse, but diverse, area of study... The volume is both an ideal go-to reference for natural resource managers and an excellent textbook for upperlevel students in conservation biology, macroecology, or resource management."
— Kate Ingenloff, Biodiversity Institute and Ecology & Evolutionary Biology, University of Kansas, Lawrence, Kansas
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Product Details

  • ISBN-13: 9780199746507
  • Publisher: Oxford University Press
  • Publication date: 12/20/2011
  • Pages: 336
  • Product dimensions: 6.10 (w) x 9.30 (h) x 0.60 (d)

Meet the Author

Milan R. Dimitrijevic, MD, PhD, Principle Investigator of Foundation for Movement Recovery, Oslo, Norway; Emeritus Professor, Baylor College of Medicine, Houston, TX.

Byron A. Kakulas, MD, FRACP, FRCPA, FRCPath, Medical Director, Australian Neuromuscular Research Institute, Nedlands, Western Australia, Australia.

W. Barry McKay, BS, Research Scientist, Norton Neuroscience Institute, Louisville, Kentucky.

Gerta Vrbová, PhD, Emeritus Professor, Division of Developmental. Neuroscience, University College London;
Visiting Professor, Royal Veterinary College, London, United Kingdom.

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Table of Contents

Contributors xvii

Part I The Clinical Practice of Restorative Neurology

1 Residual Motor Function after Spinal Cord Injury Milan R. Dimitrijevic 1

2 Neurophysiological Principles for the Assessment of Residual Motor Control Below the Spinal Cord Injury in Humans Byron A. Kakulas Keith Tansey Milan R. Dimitrijevic 10

3 Restorative Neurology of Motor Control after Spinal Cord Injury: Clinical Practice Keith Tansey MetaM. Dimitrijevic Winfried Mayr Manfred Bijak Milan R. Dimitrijevic 43

Part II Neurocontrol of Locomotion and Repair of the Injured Spinal Cord

4 Neural Control of Locomotion Gerta Vrbovó Urszula Slawinska Henryk Majczynski 65

5 Summary of Strategies Used to Repair the Injured Spinal Cord Gerta Vrbovó Urszula Slawinska 93

Part III Practical Aspects of Reconstructive Neurosurgery

6 The Reconstructive Neurosurgery of Spinal Cord Injury Justin M. Brown 134

7 Criteria for Biological Interventions for Spinal Cord Injury Repair Keith Tansey Byron A. Kakulas 169

Part IV Assessment of Motor Control in Chronic and Acute Spinal Cord Injury

8 Neurophysiological Assessment of Human Motor Control and Changes Caused by Spinal Cord Injury W. Barry McKay Arthur M. Sherwood Simon F. T. Tang 181

9 Neurophysiological Monitoring of the Human Spinal Cord Functional Integrity during Surgical Interventions Vedran Deletis Francesco Sola Paolo Costa 200

10 Transcutaneous Lumbar Posterior Root Stimulation for Motor Control Studies and Modification of Motor Activity after Spinal Cord Injury Karen Minassian Ursula Hofstoetter Frank Rattay 226

Epilogue Nib G. Andresen Byron A. Kakulas Gerta Vrbovd Milan R. Dimitrijevic 256

Appendix I A Manual for the Neurophysiological Assessment of Motor Control: The Brain Motor Control Assessment (BMCA) Protocol W. Barry McKay Arthur M. Sherwood Simon F. T. Tang 261

Appendix II Academic Environment for the Development of Human Motor Control in Ljubljana Zvonka Zupanic Slavec 2285

Index 301

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