Roitt's Essential Immunology / Edition 11

Paperback (Print)
Used and New from Other Sellers
Used and New from Other Sellers
from $19.99
Usually ships in 1-2 business days
(Save 75%)
Other sellers (Paperback)
  • All (11) from $19.99   
  • New (4) from $34.26   
  • Used (7) from $19.99   
Close
Sort by
Page 1 of 1
Showing All
Note: Marketplace items are not eligible for any BN.com coupons and promotions
$34.26
Seller since 2010

Feedback rating:

(157)

Condition:

New — never opened or used in original packaging.

Like New — packaging may have been opened. A "Like New" item is suitable to give as a gift.

Very Good — may have minor signs of wear on packaging but item works perfectly and has no damage.

Good — item is in good condition but packaging may have signs of shelf wear/aging or torn packaging. All specific defects should be noted in the Comments section associated with each item.

Acceptable — item is in working order but may show signs of wear such as scratches or torn packaging. All specific defects should be noted in the Comments section associated with each item.

Used — An item that has been opened and may show signs of wear. All specific defects should be noted in the Comments section associated with each item.

Refurbished — A used item that has been renewed or updated and verified to be in proper working condition. Not necessarily completed by the original manufacturer.

New
ETA - Standard Mail takes 6-10 business days & Expedited Mail takes 4-6 business days to deliver an item. We do not ship to APO-FPO addresses.

Ships from: Missouri City, TX

Usually ships in 1-2 business days

  • Standard, 48 States
  • Standard (AK, HI)
  • Express, 48 States
  • Express (AK, HI)
$51.95
Seller since 2011

Feedback rating:

(57)

Condition: New
BOOK IS NEW AND IN EXCELLENT CONDITION. NO MARKINGS AND LIGHT SHELF WEAR. WILL SEND OUT QUICKLY.

Ships from: Altoona, PA

Usually ships in 1-2 business days

  • Canadian
  • International
  • Standard, 48 States
  • Standard (AK, HI)
  • Express, 48 States
  • Express (AK, HI)
$92.35
Seller since 2015

Feedback rating:

(333)

Condition: New
Brand New Item.

Ships from: Chatham, NJ

Usually ships in 1-2 business days

  • Canadian
  • International
  • Standard, 48 States
  • Standard (AK, HI)
  • Express, 48 States
  • Express (AK, HI)
$105.00
Seller since 2015

Feedback rating:

(214)

Condition: New
Brand new.

Ships from: acton, MA

Usually ships in 1-2 business days

  • Standard, 48 States
  • Standard (AK, HI)
Page 1 of 1
Showing All
Close
Sort by

Overview

Roitt's Essential Immunology has established itself as the book of choice for students of immunology worldwide. This excellent textbook is commonly regarded as 'the best of the immunology primers' and the eleventh edition remains at the cutting edge of this fascinating area of science.

The trademark of this book is its highly readable introduction to the subject, its emphasis on core knowledge and its excellent four-color artwork. The internationally renowned authors have extensively updated all aspects of the book to produce a new edition, which will be an invaluable resource to students of immunology and medicine.

Roitt's Essential Immunology is supported by a website at www.roitt.com This useful on-line resource includes interactive multiple-choice questions with feedback, key concepts explained with animations, further reading lists with PubMed links, and an archive of images from the book.

Read More Show Less

Editorial Reviews

From the Publisher
"What is not to love about this book? Roitt's Essential Immunology is already considered indispensable for undergraduate biology. As with past editions, it provides a simplified approach to explaining the more complicated immunological processes...as a PhD student, this book still provides a great reference, and help for any immunologist who needs to go back to basics. Every chapter provides many useful examples and great diagrams, which are also available online and ready to download for presentations and essays...Overall this book is a very useful tool in Immunology." Immunology News"

"[I]s an easy to read, highly informative textbook, ideal for a medical student or a person looking to specialise in inmmunology" GKT Gazette

Doody's Review Service
Reviewer: Byol Shin, DO (University of South Florida College of Medicine)
Description: This book reviews the principles of basic and applied immunology, immunodeficiency, tumor immunology, and autoimmune disease.
Purpose: The purpose is to provide basic concepts of immunology and apply the knowledge of basic mechanisms of innate and adaptive immunity to understanding clinical immunologic reactions against tumors, transplants, and autoimmunity.
Audience: The book is targeted to medical students, graduates, residents, and clinical and laboratory immunologists. It is also a valuable book for allergists/immunologists and fellows-in-training who wish to update their knowledge of immunology without referring to recent research literature.
Features: The initial chapters describe in detail the components of the immune system, the cellular and molecular basis of antigen recognition, and biology of B and T lymphocytes. Subsequent chapters focus on the immunology of transplantation, congenital and acquired immunodeficiency including AIDS, tumor immunology, and autoimmune disease. Each chapter is well organized with clear tables and diagrams to aid in discussion and understanding of the material and many excellent photographs and electron micrographs illustrate the text. Chapters conclude with a summary, concise diagrams, and suggestions for further reading with extensive reference lists.
Assessment: This book provides a comprehensive, concise, up-to-date review of modern immunology. Its greatest strength is that it is a very readable account of important aspects of current immunology, and it is well written and attractively illustrated with abundant diagrams, figures, charts and tables.
Read More Show Less

Product Details

  • ISBN-13: 9781405136037
  • Publisher: Wiley, John & Sons, Incorporated
  • Publication date: 8/18/2006
  • Series: Essentials Series
  • Edition description: REV
  • Edition number: 11
  • Pages: 496
  • Product dimensions: 8.70 (w) x 10.90 (h) x 0.96 (d)

Meet the Author

Professor Ivan Roitt, University College London

Dr Peter Delves, University College London

Professor Dennis Burton, Scripps Research Institute

Professor Seamus Martin, Trinity College, Dublin

Read More Show Less

Table of Contents

1 Innate immunity.

External barriers against infection.

Phagocytic cells kill microorganisms.

Complement facilitates phagocytosis.

Complement can mediate an acute inflammatory reaction.

Humoral mechanisms provide a second defensive strategy.

Extracellular killing.

2 Specific acquired immunity.

Antibody—the specific adaptor.

Cellular basis of antibody production.

Acquired memory.

Acquired immunity has antigen specificity.

Vaccination depends on acquired memory.

Cell-mediated immunity protects against intracellular organisms.

Immunopathology.

3 Antibodies.

The division of labor.

Five classes of immunoglobulin.

The IgG molecule.

The structure and function of the immunoglobulin classes.

Genetics of antibody diversity and function.

4 Membrane receptors for antigen.

The B-cell surface receptor for antigen (BCR).

The T-cell surface receptor for antigen (TCR).

The generation of diversity for antigen recognition.

NK receptors.

The major histocompatibility complex (MHC).

5 The primary interaction with antigen.

What antibodies see.

Identifying B-cell epitopes on a protein.

Thermodynamics of antibody–antigen interactions.

Specificity and cross-reactivity of antibodies.

What the T-cell sees.

Processing of intracellular antigen for presentation by Class I MHC.

Processing of antigen for Class II MHC presentation follows a different pathway.

Cross-presentation for activation of naive CD8+ T-cells.

The nature of the ‘groovy’ peptide.

The αβ T-cell receptor forms a ternary complex with MHC and antigenic peptide.

T-cells with a different outlook.

Superantigens stimulate whole families of lymphocyte receptors.

The recognition of different forms of antigen by B- and T-cells is advantageous to.

the host.

6 Immunological methods and applications.

Making antibodies to order.

Purification of antigens and antibodies by affinity chromatography.

Modulation of biological activity by antibodies.

Immunodetection of antigen in cells and tissues.

Detection and quantitation of antigen by antibody.

Epitope mapping.

Estimation of antibody.

Detection of immune complex formation.

Isolation of leukocyte subpopulations.

Gene expression analysis.

Assessment of functional activity.

Genetic engineering of cells.

7 The anatomy of the immune response.

The need for organized lymphoid tissue.

Lymphocytes traffic between lymphoid tissues.

Lymph nodes.

Spleen.

The skin immune system.

Mucosal immunity.

Bone marrow can be a major site of antibody synthesis.

The enjoyment of privileged sites.

The handling of antigen.

8 Lymphocyte activation.

Clustering of membrane receptors leads to their activation.

T-lymphocytes and antigen-presenting cells interact through several pairs of.

accessory molecules.

The activation of T-cells requires two signals.

Protein tyrosine phosphorylation is an early event in T-cell signaling.

Downstream events following TCR signaling.

B-cells respond to three different types of antigen.

The nature of B-cell activation.

9 The production of effectors.

Cytokines act as intercellular messengers.

Different T-cell subsets can make different cytokine patterns.

Activated T-cells proliferate in response to cytokines.

T-cell effectors in cell-mediated immunity.

Proliferation and maturation of B-cell responses are mediated by cytokines.

What is going on in the germinal center?.

The synthesis of antibody.

Immunoglobulin class switching occurs in individual B-cells.

Factors affecting antibody affinity in the immune response.

Memory cells.

10 Control mechanisms.

Antigens can interfere with each other.

Complement and antibody also play a role.

Activation-induced cell death.

T-cell regulation.

Idiotype networks.

The influence of genetic factors.

Regulatory immunoneuroendocrine networks.

Effects of diet, exercise, trauma and age on immunity.

11 Ontogeny and phylogeny.

Hematopoietic stem cells.

The thymus provides the environment for T-cell differentiation.

T-cell ontogeny.

T-cell tolerance.

B-cells differentiate in the fetal liver and then in bone marrow.

B-1 and B-2 cells represent two distinct populations.

Development of B-cell specificity.

The induction of tolerance in B-lymphocytes.

Natural killer (NK) cell ontogeny.

The overall response in the neonate.

The evolution of the immune response.

The evolution of distinct B- and T-cell lineages was accompanied by the development.

of separate sites for differentiation.

Cellular recognition molecules exploit the immunoglobulin gene superfamily.

12 Adversarial strategies during infection.

Inflammation revisited.

Extracellular bacteria susceptible to killing by phagocytosis and complement.

Bacteria which grow in an intracellular habitat.

Immunity to viral infection.

Immunity to fungi.

Immunity to parasitic infections.

13 Vaccines.

Passively acquired immunity.

Vaccination.

Killed organisms as vaccines.

Live attenuated organisms have many advantages as vaccines.

Subunit vaccines containing individual protective antigens.

Epitope-specific vaccines may be needed.

Current vaccines.

Vaccines under development.

Vaccines against parasitic diseases have proved particularly difficult to develop.

Vaccines for protection against bioterrorism.

Immunization against cancer.

Other applications for vaccines.

Adjuvants.

.

14 Immunodeficiency.

Deficiencies of innate immune mechanisms.

Primary B-cell deficiency.

Primary T-cell deficiency.

Combined immunodeficiency.

Recognition of immunodeficiencies.

Treatment of primary immunodeficiencies.

Secondary immunodeficiency.

Acquired immunodeficiency syndrome (AIDS).

15 Hypersensitivity.

Anaphylactic hypersensitivity (Type I).

Antibody-dependent cytotoxic hypersensitivity (Type II).

Immune complex-mediated hypersensitivity (Type III).

Cell-mediated (delayed-type) hypersensitivity (Type IV).

Stimulatory hypersensitivity (Type V).

‘Innate’ hypersensitivity reactions.

16 Transplantation.

Genetic control of transplantation antigens.

Some other consequences of MHC incompatibility.

Mechanisms of graft rejection.

The prevention of graft rejection.

Is xenografting a practical proposition?.

Stem cell therapy.

Clinical experience in grafting.

The fetus is a potential allograft.

17 Tumor immunology.

Cellular transformation and immune surveillance.

Tumor antigens.

Spontaneous immune responses to tumors.

Tumor escape mechanisms.

Unregulated development gives rise to lymphoproliferative disorders.

Approaches to cancer immunotherapy.

Immunodiagnosis of solid tumors.

18 Autoimmune diseases.

The scope of autoimmune diseases.

Nature and nurture.

Autoreactivity comes naturally.

Is autoimmunity driven by antigen?

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)