The current study sought to examine the role of negative affect as a potential mediator between sex and Wisconsin Card Sorting Test (WCST) perseveration in one hundred and twenty-five individuals with schizophrenia and schizoaffective disorder recruited from a local outpatient facility. A mediator model was proposed based on the literature that shows (a) individuals with schizophrenia are more perseverative, (b) negative affect may influence perseveration, and (c) females evidence more negative affect in ...
The current study sought to examine the role of negative affect as a potential mediator between sex and Wisconsin Card Sorting Test (WCST) perseveration in one hundred and twenty-five individuals with schizophrenia and schizoaffective disorder recruited from a local outpatient facility. A mediator model was proposed based on the literature that shows (a) individuals with schizophrenia are more perseverative, (b) negative affect may influence perseveration, and (c) females evidence more negative affect in schizophrenia than do males. Secondary analyses also examined interactions between sex and measures of negative affect on WCST perseveration. Although the results showed an absence of mediation, sex was identified as a moderator between anxiety and WCST perseveration and between anger and WCST perseveration in the entire sample of individuals with schizophrenia (n = 75) and schizoaffective disorder (n = 50) on the basis of significant sex by affect (anxiety and anger) interactions through analyses of variance. Separate analyses revealed that although no significant effects were identified among individuals with schizophrenia, a main effect of depression on perseveration as well as sex by anxiety and sex by negative affect interactions were identified among those with schizoaffective disorder. For each significant interaction, males performed worse at higher levels of affect than at lower levels of affect, while the reverse was true for females. These findings are discussed as are the implications for the two models (mediator versus moderator).
Product dimensions: 7.44 (w) x 9.69 (h) x 0.25 (d)
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