Rossi's Principles of Transfusion Medicine / Edition 3

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Rossi's Principles of Transfusion Medicine is the most comprehensive and practical reference on transfusion science and medicine available. It features brand new chapters on the measurement of cell kinetics, obstetric transfusion practice, cord blood, transfusion alternatives and regenerative medicine. Produced jointly with AABB, the world's leading association in the fields of blood banking and transfusion medicine, it now has two companion CD-ROMs-one containing interactive case studies and one containing PDFs of all 66 chapters.

Thoroughly revised and updated, this volume is the most comprehensive, current, and practical reference on transfusion science and medicine. The book is now divided into six major sections with subsections organized around the biology and clinical use of blood components and derivatives; the transfusion needs of specific patient groups; and disease transmission and transfusion reactions. The blending of transfusion sciences with clinical concerns has been strengthened in this edition, and includes 26 case studies based on actual patients. Other Third Edition highlights include new chapters on specialized therapeutic hemapheresis procedures, transfusion-transmitted infection risk, prion transmission, and pathogen reduction.

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Editorial Reviews

Doody's Review Service
Reviewer: Valerie L. Ng, PhD MD(Alameda County Medical Center/Highland Hospital)
Description: This is an updated comprehensive textbook of transfusion medicine.
Purpose: The goal of this third edition is to maintain the excellence of the previous editions while providing state-of-the-art information about new and emerging areas within transfusion medicine and transfusion science (e.g., prion transmission, therapeutic hemapheresis, etc.). The intent of this edition is to focus on the medicine and science of transfusion, while giving less consideration to its technical aspects. The editors and individual chapter authors have succeeded admirably in achieving this ambitious goal.
Audience: This book would be useful to anyone interested in transfusion medicine and transfusion science. It would appeal especially to those subspecialists (e.g., pathologists, hematologists) with a significant clinical practice in transfusion medicine.
Features: After reading a few chapters of this book, I was in awe. This 69-chapter book is truly a comprehensive archetype tome of transfusion medicine. The list of authors and editors reads like a "Who's Who" in transfusion medicine, and the information is accordingly incomparable in terms of each author's expertise in and insight into a particular transfusion medicine niche. The book starts with a fascinating chapter on the historical origins of transfusion medicine followed by sections of chapters devoted to blood components and derivatives, clinical practice, apheresis, adverse sequelae, special topics, and delivery of blood services. A unique aspect of this edition is the arrangement of information for each subject. The chapters are arranged in a logical and seemingly seamless spectrum starting with the basic science of the particular topic, moving to the translational laboratory aspects, and concluding with clinical applications or practice. This assembly of information results in the reader gaining a multifaceted understanding of the topic. The information in each chapter is current and thoroughly discussed, with critical analysis of relevant publications. The references are quite extensive and complete.
Assessment: This is a great book. It has admirably continued the noble tradition and excellence of the previous two editions. I highly recommend it for anyone involved in the practice of transfusion medicine — it's a must-have.
From The Critics
New edition of a reference that blends transfusion sciences with clinical concerns. The 69 contributions are divided into sections on blood components and derivatives, clinical practice, apheresis, adverse sequelae, special topics, and delivery of blood services. Sub- topics include the biology and clinical use of various blood components, the transfusion needs of specific patient groups, and disease transmission and transfusion reactions. New material includes coverage of specialized therapeutic hemapheresis procedures, an overview of risk of transfusion-transmitted disease, prion transmission, and pathogen reduction, as well as case studies. Edited by Simon (U. of New Mexico School of Medicine), Walter H. Dzik and Christopher P. Stowell (Massachusetts General Hospital), Edward L. Snyder (Yale U. School of Medicine), and Ronald G. Strauss (U. of Iowa College of Medicine). Annotation c. Book News, Inc., Portland, OR

4 Stars! from Doody
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Product Details

  • ISBN-13: 9780781730242
  • Publisher: Lippincott Williams & Wilkins
  • Publication date: 6/28/2002
  • Edition description: Third Edition
  • Edition number: 3
  • Pages: 983
  • Product dimensions: 8.20 (w) x 11.10 (h) x 2.20 (d)

Meet the Author

Toby L. Simon, MD, Corporate Medical Director, ZLB Plasma, a CSL Behring company, Boca Raton, Florida and Clinical Professor, Department of Pathology, University of New Mexico School of Medicine, Albuquerque, New Mexico

Edward L Snyder, MD, Professor, Laboratory Medicine, Yale-New Haven Hospital, USA

Christopher P. Stowell, MD, PhD, Director, Blood Transfusion Service, Massachusetts General Hospital and Assistant Professor of Pathology, Harvard Medical School, Boston, Massachusetts, USA

Ronald G. Strauss, MD, Professor of Pathology and Pediatrics, University of Iowa College of Medicine, Iowa City, USA

Bjarte G. Solheim, PhD, MHA, Professor/Head Physician, Institute of Immunology, Rikshospitalet, Oslo, Norway

Marian Petrides, MD, Associate Professor of Clinical Pathology, University of Missouri School of Medicine and Medical Director,Transfusion Service and Coagulation Laboratory, University of Missouri Health Care, Columbia, Missouri, USA

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Table of Contents

1. Transfusion in the New Millennium 1
Section I Blood Components and Derivatives
Part I Red Blood Cell
2. Red Blood Cell Production and Kinetics 14
3. Hemoglobin Synthesis, Structure and Oxygen Transport 25
4. Red Blood Cell Metabolism 43
5. Liquid Preservation of Red Blood Cells 50
6. Frozen Preservation of Red Blood Cells 62
7. Red Blood Cell Immunology and Compatibility Testing 69
Case 7A. Knowing When To Ask for Help 89
8. Human Carbohydrate Blood Group Systems 92
Case 8A. A French Canadian with a Rare Blood Type 111
9. Rh and LW Blood Group Systems 113
Case 9A. Who's My Daddy? 123
10. Other Protein Blood Group Antigens 125
Case 10A. The Awful Allos: Managing the Patient with Multiple Alloantibodies 135
11. Erythrocytosis and Therapeutic Phlebotomy 138
12. Anemia and Red Blood Cell Transfusion 149
13. Red Blood Cell Substitutes 165
Part II Platelets
14. Megakaryocytopoiesis, Kinetics, and Radiolabeling 177
15. Platelet Kinetics and Hemostasis 192
16. Platelet Immunology and Alloimmunization 203
Case 16A. If at First You Don't Succeed, Sometimes You Should Not Try Again 218
17. Preparation and Storage of Platelet Concentrates 220
18. Platelet Transfusion and Alternatives 232
Case 18A. Interconnected Cascades 248
Part III White Blood Cell
19. Neutrophil Production and Kinetics: Neutropenia and Neutrophilia 250
20. Neutrophil Collection and Transfusion 258
Case 20A. Is G-CSF Leukemogenic? 268
21. Leukoreduced Blood Components: Laboratory and Clinical Aspects 270
Part IV Plasma
22. Plasma Composition and Coagulation Mechanism 288
23. Preparation of Plasma Derivatives 304
24. Immunoglobins in Clinical Medicine 316
Case 24A. Unexpected Thrombocytopenia Before Surgery 333
25. Plasma Transfusion and Alternatives 335
Case 25A. Danger in Treating the Numbers 341
Section II Clinical Practice
Part I Medical Patient
26. Autoimmune Hemolytic Anemia and Paroxysmal Nocturnal Hemoglobinuria 345
27. Management of Immune Thrombocytopenia 367
Case 27A. A Diagnosis You Don't Want to Miss 396
28. Bleeding from Acquired Coagulation Defects and Antithrombotic Therapy 399
Case 28A. It Seemed Like a Magic Potion 415
Part II Pediatric, Obstetric, Congenital
29. Fetal and Neonatal Hematopoiesis 417
30. Hemolytic Disease of the Fetus or Newborn: Treatment and Prevention
Case 30A. New Treatment for an Old Problem 446
31. Congenital Disorders of Clotting Proteins and their Management 448
32. Management of Congenital Hemolytic Anemias 463
Case 32A. A Delayed Hemolytic Transfusion Reaction Run Amok 483
33. Neonatal Red Blood Cell, Platelet, Plasma, and Neutrophil Transfusions 486
Part III Oncology Patients
34. Transfusion Support for the Oncology Patient 498
Case 34A. First Things First 511
35. Hematopoietic Growth Factors (Cytokines)
36. Processing and Preservation of Hematopoietic Progenitor Cells 522
Case 36A. Where Am I? 534
37. Human Progenitor Cell-Autologous Transplantation 537
38. Blood and Marrow Transplantation 555
Case 38A. Break on Through to the Other Side 570
39. Adoptive Immunotherapy 573
40. Gene Therapy in Transfusion Medicine 580
Part IV Surgery Patients
41. Red Blood Cell Support in the Perioperative Setting 590
42. Coagulation Support in the Perioperative Setting 602
43. Transfusion Therapy in Solid-Organ Transplantation 622
44. Transfusion Therapy in the Care of Trauma and Burn Patients 632
Case 44A. Emergency Transfusion 644
Section III Apheresis
45. Apheresis: Principles and Technology of Hemapheresis 648
Case 45A. A Call One Saturday Morning 659
46. Therapeutic Plasma Exchange 662
Case 46A. What's Your Diagnosis? 683
47. Specialized Therapeutic Hemapheresis Procedures 685
Case 47A. Too Much Dust in the Blood 699
Section IV Adverse Sequelae
Part I Disease Transmission
48. Transfusion-Transmitted Infection Risk from Blood Components and Plasma Derivatives 703
49. Transfusion-Transmitted Hepatitis C and Non A, Non B, Non C Virus Infections 718
50. Transfusion-Transmitted Hepatitis B, A, and D 733
51. Retroviral Infections 742
52. Cytomegalovirus and Parvovirus Transmission by Transfusion
Case 52A. CMV Infection in an Immunosuppressed Infant 772
53. Transmission of Parasitic Infections by Blood Transfusion 774
Case 53A. Fever after Blood Transfusion 782
54. Transmission of Creutzfeldt-Jakob Disease by Transfusion 784
55. Bacterial Contamination of Blood Products 789
Case 55A. It Ain't Over 'Till It's Over 802
56. Pathogen Inactivation in Blood Components 806
Part II Transfusion Reactions
57. Hemolytic Transfusion Reactions 815
Case 57A. A Hemolytic Transfusion Reaction: Doing it the Hard Way 829
58. Febrile, Allergic, and Non-Immune Transfusion Reactions 831
59. Transfusion-Associated Graft Versus Host Disease 852
Case 59A. 'O'h It's Back 'A'-gain 865
60. Transfusion-Associated Immunomodulation 867
Section V Special Topics
61. Red Blood Cell Radiolabeling and In Vivo Kinetics 879
62. HLA and Molecular Testing 886
63. Parentage Testing 898
64. Tissue Banking 912
65. Medicolegal Aspects of Blood Transfusion 927
Case 65A. Elective Surgery in a Jehovah's Witness 940
Section VI Delivery of Blood Services
66. Organization of Blood Services in the United States 944
67. International Aspects of Blood Services 953
68. Current Good Manufacturing Practices 958
69. Hospital Transfusion Services and Quality Assurance 972
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