Rossi's Principles of Transfusion Medicine [With 2 CDROMs] / Edition 4

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Rossi's Principles of Transfusion Medicine" is the most comprehensive and practical reference on transfusion science and medicine available. It features brand new chapters on the measurement of cell kinetics, obstetric transfusion practice, cord blood, transfusion alternatives, regenerative medicine. Produced jointly with AABB, the world's leading association in the fields of blood banking and transfusion medicine, it now has two companion CD-ROMs - one containing interactive case studies and one containing PD's of all 66 chapters.

Thoroughly revised and updated, this volume is the most comprehensive, current, and practical reference on transfusion science and medicine. The book is now divided into six major sections with subsections organized around the biology and clinical use of blood components and derivatives; the transfusion needs of specific patient groups; and disease transmission and transfusion reactions. The blending of transfusion sciences with clinical concerns has been strengthened in this edition, and includes 26 case studies based on actual patients. Other Third Edition highlights include new chapters on specialized therapeutic hemapheresis procedures, transfusion-transmitted infection risk, prion transmission, and pathogen reduction.

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Editorial Reviews

From the Publisher
"It is an enjoyable book to read, as well as a very good reference too, not just for the transfusion lab and on haematologists' shelves, but also in general libraries." (Royal College of Pathologists, 1 April 2011)

"The list of contributing authors includes some of the most well-known experts in different areas of transfusion medicine and its related areas.” (European Journal of Haematology, 2010)

"Rossi's Principles of Transfusion Medicine is the most comprehensive and practical reference on transfusion science and medicine available." (Doody's Reviews, June 2009)

Doody's Review Service
Reviewer: Valerie L. Ng, PhD MD(Alameda County Medical Center/Highland Hospital)
Description: This is the fourth edition of a book with a longstanding and well deserved reputation of being one of only a few must-have transfusion medicine references. The previous edition was published in 2002.
Purpose: The purpose is to provide a comprehensive and clinically relevant reference for transfusion medicine practitioners.
Audience: The book is intended for transfusion medicine practitioners and students (pathology or laboratory medicine residents, transfusion medicine fellows, clinical hematology fellows). It also would be of interest to any practitioner or student of any field in medicine using transfusion for patient care. Lastly, this would be of interest to nonphysician laboratory personnel, such as practicing clinical laboratory scientists (CLSs), especially those specializing in blood banking, and CLS student trainees.
Features: This hefty tome (2 inches thick, 66 chapters) lives up to its promise and contains clinically relevant information for practicing transfusion medicine specialists. Entire chapters are devoted to transfusion medicine issues unique to specific medical disciplines (e.g., obstetrics, neonates, oncology, surgery, etc.). I was absolutely enthralled with Walter Dzik's chapter on blood components to achieve hemostasis for surgery and invasive procedures. For all of you out there fighting for appropriate use of frozen plasma (FP), this is the chapter you need. It contains a thorough review of the limited evidence for FP use. Before this, I would have to juggle five different published references to make my point. Now it's all there in one concise chapter that's easy to access, easy to quote, and easy to make a cogent and convincing clinical consultation for or against FP use. Hemovigilance is also well covered in this edition, especially the ISBT classification schemes for standardized transfusion reaction reporting. The only thing I wanted but couldn't find was a comparison of the reproducibility of the ISBT classification scheme with that reported in the "revised classification scheme for acute transfusion reactions" (Sanders et al., Transfusion 2007;47:621). Which classification scheme is more reproducible? Is one superior to the other? Finally, this edition comes with two really useful CDs. One is the entire text of the book, searchable by keyword. No longer do you have to lug around this heavy book if you put the information on a lightweight electronic gizmo. (Imagine how brilliant you will look on clinical rounds!) The other contains a compilation of case studies, useful for teaching residents/fellows and for practicing transfusion medicine practitioners to refresh or update their knowledge. Very nice!
Assessment: This is a must-have for any transfusion medicine practitioner.
From The Critics
New edition of a reference that blends transfusion sciences with clinical concerns. The 69 contributions are divided into sections on blood components and derivatives, clinical practice, apheresis, adverse sequelae, special topics, and delivery of blood services. Sub- topics include the biology and clinical use of various blood components, the transfusion needs of specific patient groups, and disease transmission and transfusion reactions. New material includes coverage of specialized therapeutic hemapheresis procedures, an overview of risk of transfusion-transmitted disease, prion transmission, and pathogen reduction, as well as case studies. Edited by Simon (U. of New Mexico School of Medicine), Walter H. Dzik and Christopher P. Stowell (Massachusetts General Hospital), Edward L. Snyder (Yale U. School of Medicine), and Ronald G. Strauss (U. of Iowa College of Medicine). Annotation c. Book News, Inc., Portland, OR

4 Stars! from Doody
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Product Details

  • ISBN-13: 9781405175883
  • Publisher: Wiley
  • Publication date: 2/28/2009
  • Edition number: 4
  • Pages: 1110
  • Product dimensions: 9.10 (w) x 11.20 (h) x 2.30 (d)

Meet the Author

Toby L. Simon, MD, Corporate Medical Director, ZLB Plasma, a CSL Behring company, Boca Raton, Florida and Clinical Professor, Department of Pathology, University of New Mexico School of Medicine, Albuquerque, New Mexico

Edward L Snyder, MD, Professor, Laboratory Medicine, Yale-New Haven Hospital, USA

Christopher P. Stowell, MD, PhD, Director, Blood Transfusion Service, Massachusetts General Hospital and Assistant Professor of Pathology, Harvard Medical School, Boston, Massachusetts, USA

Ronald G. Strauss, MD, Professor of Pathology and Pediatrics, University of Iowa College of Medicine, Iowa City, USA

Bjarte G. Solheim, PhD, MHA, Professor/Head Physician, Institute of Immunology, Rikshospitalet, Oslo, Norway

Marian Petrides, MD, Associate Professor of Clinical Pathology, University of Missouri School of Medicine and Medical Director,Transfusion Service and Coagulation Laboratory, University of Missouri Health Care, Columbia, Missouri, USA

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Table of Contents



1 Transfusion in the New Millennium: Ennio C. Rossi and Toby L. Simon.

Section I. Blood Components and Derivatives.

Part I. Red Blood Cells.

2 Red Cell Production and Kinetics: Mark J. Koury.

3 Regulation of Oxygen Delivery by Red Cells and Red Cell Substitutes: Christopher P. Stowell.

4 Red Blood Cell Metabolism and Preservation: Bjarte G. Solheim and John R. Hess.

5 Red Cell Immunology and Compatibility Testing: W. John Judd.

6 Carbohydrate Blood Groups: Eldad A. Hod, Patrice Spitalnik and Steven L. Spitalnik.

7 Rh and LW Blood Groups: Connie M. Westhoff and Don L. Siegel.

8 Other Protein Blood Groups: Petr Jarolim.

9 Anemia and Red Blood Cell Transfusion: Jeffrey L. Carson and Paul C. Hébert.

Part II. Platelets.

10 Platelet Production, Kinetics, and Hemostasis: Henry M. Rinder and Aaron Tomer.

11 Platelet Immunology and Alloimmunization: Brian R Curtis and Janice G. McFarland.

12 Preparation, Preservation, and Storage of Platelet Concentrates: Ralph R. Vassallo, Jr.

13 Thrombocytopenia and Platelet Transfusio: Peter W. Marks.

Part III. White Blood Cells.

14 Neutrophil Production and Kinetics: Neutropenia and Neutrophilia: Thomas H. Price.

15 Neutrophil Collection and Transfusion: Ronald G. Strauss.

16 Leukocyte-Reduced Blood Components: Laboratory and Clinical Aspects: Darrell J. Triulzi and Walter H. Dzik.

Part IV. Plasma.

17 Composition and Mechanisms of Blood Coagulation and Fibrinolysis: Peter Hellstern.

18 Immunoglobulins: Urs E. Nydegger.

19 Preparation and Use of Plasma Derivatives: Toby L. Simon, Kirsten Seidel and Albrecht Gröner.

20 Plasma Transfusion and Use of Albumin: Simon J. Stanworth and Alan T. Tinmouth.

Part V. Cell Kinetics.

21 Applications of Cellular Radiolabeliing in Transfusion Medicine: Larry J. Dumont, James P. AuBuchon and Richard J. Davey).

Section II. Clinical Practice.

Part I. Medical Patients.

22 Autoimmune Hemolytic Anemia and Paroxysmal Noctural Hemoglobinuria: Thomas P. Duffy.

23 Management of Immune Thrombocytopenias: Donald M. Arnold, James W. Smith and Theodore Warkentin.

24 Bleeding from Acquired Coagulation Defects and Antithrombotic Therapy: Thomas J. Raife, Jeffry S. Rose and Steven R. Lentz.

Part II. Obstetric and Pediatric Patients.

25 Fetal and Neonatal Hematopoiesis: Robert D. Christensen and Martha C. Sola-Visner.

26 Obstetric Transfusion Practice: Humphrey H.H. Kanhai, Jos J.M. van Roosmalen and Anneke Brand.

27 Hemolytic Disease of the Newborn: Bjarte G. Solheim and Morten Grönn.

28 Congenital Disorders of Clotting Proteins and Hypercoagulable States in Pediatrics: Linda J. Butros and Prasad Mathew.

29 Management of Congenital Hemolytic Anemias: Bruce I. Sharon.

30 Blood Component Transfusions for Infants: Ronald G. Strauss.

Part III. Oncology Patients.

31 Transfusion Support for the Oncology Patient: Christopher A. Tormey and Edward L. Snyder.

32 Hematopoietic Growth Factors (Cytokines): W. Conrad Liles and David C. Dale.

33 Hematopoietic Progenitor Cells: Biology and Processing: Thomas Leemhuis and Ronald A. Sacher.

34 Hematopoietic Progenitor Cells: Autologous Transplantation: Hooman H. Rashidi and Scott D. Rowley.

35 Hematopoietic Progenitor Cells: Allogeneic Transplantation: Amin M. Alousi and Sergio A. Giralt.

36Umbilical Cord Blood: A Reliable Source of Stem and Progenitor Cells for Human Transplantation: Suhag H. Parikh and Joanne Kurtzberg.

Part IV. Surgery Patients.

37 Alternatives to Transfusion: Perioperative Blood Management: Lynne Uhl.

38 Blood Components to Achieve Hemostasis for Surgery and Invasive Procedures: Walter H Dzik.

39 Transfusion Therapy in the Care of Trauma and Burn Patients: Ellen C. Omi and Richard L. Gamelli.

40 Transfusion Therapy in Solid-Organ Transplantation: Glenn Ramsey.

Section III. Apheresis.

41 Apheresis: Principles and Technology of Hemapheresis: Ronald O. Gilcher and James W. Smith.

42 Therapeutic Plasma Exchange Bruce C. McLeod.

43 Specialized Therapeutic Hemapheresis and Phlebotomy: Robert Weinstein.

Section IV. Hazards of Transfusion.

Part I - Hemovigilance.

44 Overview of Hemovigilance: Dorothy Stainsby, Jean-Claude Faber and Jan Jørgensen.

45 Immunomodulatory and Proinflammatory Effects of Allogeneic Blood Tranfusion: Eleftherios C. Vamvakas, José O. Bordin and Morris A. Blajchman.

Part II. Infectious Hazards of Transfusion.

46 Transfusion-Transmitted Hepatitis: Harvey J. Alter and Juan I. Esteban-Mur.

47 Retroviruses and Other Viruses: John A. J. Barbara and Brian Dow.

48 Transfusion Transmission of Parasites: Bryan R. Spencer.

49 Bacterial Contamination of Blood Products: Yara A. Park and Mark E. Brecher.

50 Prion Diseases: Marc L. Turner.

51 Pathogen Inactivation: Bjarte G. Solheim and Jerard Seghatchian.

Part III - Noninfectious Hazards.

52 Hemolytic Transfusion Reactions: Robertson D. Davenport.

53 Febrile, Allergic, and Nonimmune Transfusion Reactions: Gregory J. Pomper.

54 Transfusion-Associated Graft-vs-Host Disease: John E. Levine and James L. M. Ferrara.

55 Tranfusional Iron Overload: Sujit Sheth.

56 Transfusion-Related Acute Lung Injury: Jonathan P. Wallis and Ulrich J. H. Sachs.

Section V. Cell and Tissue Therapy.

57 HLA Antigens and Alleles: Thomas M. Williams.

58 Tissue Banking: Jeanne V. Linden, William F. Zaloga and A. Bradley Eisenbrey.

59 Adoptive Immunotherapy: Catherine M. Bollard and Helen Heslop.

60 Gene Therapy in Transfusion Medicine: Emanuela M. Bruscia and Diane S. Krause.

61 Tissue Engineering and Regenerative Medicine: Clay Quint and Laura Niklason.

Section VI. Delivery of Transfusion and Transplantation Services.

62 Recruitment and Screening of Donors and the Collection, Processing, and Testing of Blood: Kendall P Crookston, Susan L. Wilkinson and Toby L. Simon.

63 Current Legal Issues in Transfusion Medicine: Edward M. Mansfield, Thomas K. Berg, Kurt A. Leiheit, John Parker Sweeny and P. Robert Rigney.

64 Current Good Manufacturing Practice: P Ann Hoppe and Sheryl A. Kochman.

65 Transplant Organizations and Networks in the Regulation of Cellular Therapy Programs: Dennis L. Confer.

66 Hospital Transfusion Committee and Quality Assurance: Pamela Clark and Paul D. Mintz.


Companion PC and Mac Compatible CD-ROMs.

CD-ROM 1: All chapters of the book with a full text search function.

CD-ROM 2: Cases.

1 Posttransfusion Hemolysis: Marian Petrides and Nicole A. Pele.

2 Child with Low Fibrinogen: Marian Petrides and Donna Castellone.

3 Head Injury, Sudden Dyspnea: Marian Petrides.

4 A Transfusion Fatality: Marian Petrides.

5 Platelet Refractoriness: Marian Petrides.

6 An Unexpected Panagglutinin: Marian Petrides.

7 Postsurgical Bleeding: Marian Petrides.

8 Jehovah's Witness Surgery: Christopher P. Stowell and Marian Petrides.

9 Delayed Fever and Dark Urine: Marian Petrides.

10 Fever in Neutropenic Child: Marian Petrides and Dava S. Cleveland-Noriega

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