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Doody's Review ServiceReviewer: Leonor David, MD, PhD (IPATIMUP)
Description: This is the fourth edition of a book that presents a comprehensive clinicopathologic overview of human disease. The book has an excellent balance of medical nomenclature, molecular basis of disease, clinical features, epidemiology, pathogenesis, and pathology. The third edition was published in 2001.
Purpose: The purpose is to give students in medical sciences the basic knowledge about pathology needed to understand and handle human diseases. The purpose is fully met through the book's careful and systematic approach that relates pathologic changes to clinical manifestations of disease.
Audience: The book is written for students of medical sciences, according to the editor. It is also a useful book for researchers from nonmedical sciences working on molecular biology of human diseases and for residents from essentially all medical specialties.
Features: The book covers general mechanisms involved in the pathogenesis of human diseases, using well selected models of cell/molecular biology based information. It does not fall into the trap of getting students lost with redundant, sometimes spurious, molecular biology data. In the second part, systemic pathology is covered, with short introductions on normal anatomy and histology. It includes the classic organ approach and innovative chapters on diseases like diabetes and amyloidosis, that serve as examples to give readers more in-depth information about relevant diseases with a lot of new information from recent years. Drawings, diagrams, and images are of excellent quality.
Assessment: This is an excellent book where students, researchers, and professionals in medical sciences will find "pathology literacy," as the editor puts it in the preface. The clinicopathologic approach used throughout and the excellent quality of figures and illustrations are major advantages of this book compared to others in the field.