BN.com Gift Guide

Same Cure

Overview

Can one pill fix everything from aching joints to flaggingspirits? SAMe, a naturally-occurring molecule that is part of allliving things, is a breakthrough supplement that has beenused successfully for two decades in Europe to treat both arthritis and depression. Found to be effective against major depression andmild blues within one week, it also shows amazing results in bringing relief from other ills, including arthritis, fibromyalgia, liver disease, Parkinson's disease and Alzheimer's disease. This Q&A ...

See more details below
Available through our Marketplace sellers.
Other sellers (Paperback)
  • All (16) from $1.99   
  • New (1) from $30.81   
  • Used (15) from $1.99   
Close
Sort by
Page 1 of 1
Showing All
Note: Marketplace items are not eligible for any BN.com coupons and promotions
$30.81
Seller since 2014

Feedback rating:

(320)

Condition:

New — never opened or used in original packaging.

Like New — packaging may have been opened. A "Like New" item is suitable to give as a gift.

Very Good — may have minor signs of wear on packaging but item works perfectly and has no damage.

Good — item is in good condition but packaging may have signs of shelf wear/aging or torn packaging. All specific defects should be noted in the Comments section associated with each item.

Acceptable — item is in working order but may show signs of wear such as scratches or torn packaging. All specific defects should be noted in the Comments section associated with each item.

Used — An item that has been opened and may show signs of wear. All specific defects should be noted in the Comments section associated with each item.

Refurbished — A used item that has been renewed or updated and verified to be in proper working condition. Not necessarily completed by the original manufacturer.

New
Brand New Item.

Ships from: Chatham, NJ

Usually ships in 1-2 business days

  • Canadian
  • International
  • Standard, 48 States
  • Standard (AK, HI)
  • Express, 48 States
  • Express (AK, HI)
Page 1 of 1
Showing All
Close
Sort by
Sending request ...

Overview

Can one pill fix everything from aching joints to flaggingspirits? SAMe, a naturally-occurring molecule that is part of allliving things, is a breakthrough supplement that has beenused successfully for two decades in Europe to treat both arthritis and depression. Found to be effective against major depression andmild blues within one week, it also shows amazing results in bringing relief from other ills, including arthritis, fibromyalgia, liver disease, Parkinson's disease and Alzheimer's disease. This Q&A gives you all the most up-to-date information on this miraculousdietary treatment now available in the U.S.—

  • How SAMe works to treat depression
  • The safety and effectiveness of SAMe
  • A comprehensive overview of commonly used prescription and on-prescription antidepressants, and how they compare with SAMe
  • Arthritis causes and treatments
  • Why the SAMe treatment is superior to anything currently offered for relief of arthritis
  • All about the mysterious disease fibromyalgia: its possible causes, symptoms, common treatments, and how SAMe can bring relief
  • Strong scientific evidence that SAMe works as a treatment for liver disease
  • Relief from many of the side effects of Parkinson's disease
  • Promising evidence that SAMe may slow down the progression of Alzheimer's disease
  • and much more!
Read More Show Less

Product Details

  • ISBN-13: 9780380814404
  • Publisher: HarperCollins Publishers
  • Publication date: 8/8/2000
  • Format: Mass Market Paperback
  • Pages: 256
  • Product dimensions: 4.18 (w) x 6.75 (h) x 0.64 (d)

Meet the Author

A graduate of Harvard, Dan Klein is the author or co-author of twelve books of non-fiction, most of them on psychological subjects. He lives in Great Barrington, Massachusetts, with his wife and daughter. Dr. David W. Johnson is an Associate Professor in the Department of Pharmacology and Physiology at the College of Osteopathic Medicine, University of New England, and Adjunct Professor in the Department of Physiology and Experimental Therapeutics at the Boston University School of Medicine.

Read More Show Less

Read an Excerpt

"Cure du Jour"
or Medical Breakthrough?

Medical "miracles" have been appearing on the market fast and furiously over the last 10 years. Melatonin, DHEA, St. John's wort, shark's fin cartilage, green algae-it is hard to keep count. And it's even harder to separate the medically tested preparations from the purely speculative ones.

The main reason that these new products are so hard for the consumer to judge is that federal laws governing their sale have recently changed, making it easier for new products to come on to the market (good), but also easier for these products to appear there without adequate experimental testing (not good.) Few, if any, of these new "miracle" products get onto drugstore and health-food store shelves without evidence that they are safe in moderate dosages. But whether they actually do any good—whether they actually deliver what is promised—frequently remains in question.

And now, along comes S-adenosylmethionine (SAMe), a naturally occurring molecule that is part of all living cells. It is being marketed as an expensive over-the-counter supplement that promises to cure — or at least significantly treat — a great number of the most prevalent and devastating diseases affecting Americans today. It is being touted as a virtual panacea, much the way the tonics and "snake oils" of the past were touted to unsuspecting and desperate consumers.

So the question is: Does SAMe actually deliver what it promises? And are there a substantial number of well-designed and executed, double-blind experimental studies that prove that it does?

The answer to both questions is a resounding yes! —at least for SAMe's most significant claims. And those include SAMe's efficacy in treating depression, osteoarthritis, cirrhosis of the liver, and fibromyalgia. (When it comes to Parkinson's disease and Alzheimer's disease, as we will see, the jury is still out, although preliminary data appears very promising indeed.)

How can one supplement have so many different beneficial effects?
SAMe's sheer variety of beneficial effects is certainly enough to make one suspicious — it sounds an awful lot like "snake oil," doesn't it? But the reason that SAMe affects so many different aspects of human biology and pathology lies in the fact that SAMe operates on a fundamental biological process known as methylation — a process that occurs over a billion times per second throughout the body. Put simply, when a substance influences a process this basic — a process that is absolutely necessary for a number of critical life functions — it is bound to influence a great many vital aspects of the body.

Let's put that in another context. We all know that water is necessary for most basic life functions. And we know that if we are deprived of adequate amounts of water, every one of our body systems will slow down and finally stop functioning, resulting in sickness and eventually death. So there is a sense in which it could be said that adding water to a dehydrated person's diet "cures" a huge number of ailments, ranging from inadequate blood cell production to reduced brain function. That may sound a little simplistic, but the point is that when you are dealing with basic biological substances and basic biological processes, the effects are obviously going to be far-reaching.

There is something else we should consider when thinking about SAMe's multiple effects. Virtually all drugs and supplements have multiple effects, but these effects are broken down into the "primary effect" and the "side effect." The primary effect is the intended effect — the one for which you are taking the drug. A side effect is the unfortunate or unwelcome effect(s) that come along with the intended effect. For example, the primary or intended effect of taking an aspirin is reducing headache pain, while the frequent side effect is an upset stomach. Another example — one that becomes quite relevant when we compare Prozac with SAMe as a treatment for depression — is that one of the many possible side effects of Prozac is reduced libido and impotence in men. Certainly some patients have come to the conclusion that in the case of Prozac, the cure is worse than the disease — or, put another way, they would say that as far as they are concerned, impotence is the primary effect of Prozac.

Consider the drug minoxidil. When it was originally developed as a treatment for high blood pressure, researchers discovered that a frequent side effect of this drug was increased hair growth. Today, minoxidil is marketed as a hair restorer for bald people with the frequent and sometimes dangerous "side effect" of lowering the user's blood pressure!

The point is simply that the various effects of a given drug or supplement are either good or bad depending on what the desired effect of that drug is. For this reason, when referring to side effects, I identify those that reasonable people do not want as "unwelcome" side effects. So the bottom line is that, yes, SAMe has a great number of effects and, happily, most of these effects are quite welcome. In fact, one of the great advantages of SAMe treatment versus, say, Prozac, is that it has virtually no unwelcome side effects.

What is methylation?
We will be looking at what SAMe is and what the methylation process consists of from a variety of perspectives as we investigate SAMe's effects on different ailments. But let's lay down the basics here.

SAMe is a molecule that is a part of all living cells. Our bodies manufacture it from an amino acid called methionine, which is found in most proteins.

Methylation is a molecular transaction in which one molecule donates a four-atom part of itself to a nearby molecule. When this happens, both the donor molecule and the recipient molecule change shape, making huge differences in the way the human body conducts business.

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)