Schizophrenia Genesis: The Origins of Madness

Schizophrenia Genesis: The Origins of Madness

by Irving I. Gottesman

ISBN-10: 0716721473

ISBN-13: 9780716721475

Pub. Date: 09/28/1990

Publisher: Holt, Henry & Company, Inc.

Sorting out fact from fiction, one of the world's leading experts presents an absorbing account of what is actually know about the complex subject of schizophrenia.

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Sorting out fact from fiction, one of the world's leading experts presents an absorbing account of what is actually know about the complex subject of schizophrenia.

Product Details

Holt, Henry & Company, Inc.
Publication date:
Series of Books in Psychology
Edition description:
Product dimensions:
6.12(w) x 9.22(h) x 0.63(d)

Table of Contents

1In the Beginning1
Early Accounts of Schizophrenia5
Historical Views of Insanity and Its Treatment: Some Misguided Clues to Causes9
Origins of Modern Considerations in Mental Disorders12
2How Do We Know When It's Schizophrenia?17
Reducing Uncertainty in Diagnosing Schizophrenia19
Genuine Schizophrenia: A Case History24
Schizophrenia's Forgeries and False Leads28
Experiments in Making Clinical Judgments30
A Prototype for Diagnosing Schizophrenia33
Diagnosing Schizophrenia: An Integrated Summary36
Schizophrenia and Childhood Psychoses37
3Anguished Voices I: Personal Accounts of Survivors40
Where Did I Go?41
The Messiah Quest44
After the Funny Farm50
The Hard Road Back54
4Schizophrenia across Time and Space60
Lessons from Epidemiology61
Is Schizophrenia a Recent Disease?63
From Raw Data toward Strategic Information64
The Age of Onset of Schizophrenia68
The Demographics of Longevity70
Attempts to Discover the True Number of Schizophrenics72
From Mental Hospital Statistics to Community Estimates73
The Distribution of Schizophrenia by Social Class76
Schizophrenia around the World79
5Is Schizophrenia Inherited Genetically?82
A Genetics Primer84
From Simple to Complex Schemes of Inheritance86
Foundations for a Genetic Position93
Family Studies94
6The Evidence from Twin Studies104
Classical Twin Studies: 1928-1953105
Contemporary Twin Studies109
Challenges to Received Wisdom114
Severity as an Indicator of Genetic Loading116
Reprise: Old and New Twin Studies116
Understanding Discordance in Identical Twins117
Revitalizing Research on Discordant Twin Pairs119
Identical Twins Reared Apart120
The Offspring of Schizophrenic Twins123
Identical Quadruplets Concordant for Schizophrenia125
Three Generations of Schizophrenia127
7Is Schizophrenia Contagious Psychologically?133
Adoption Strategies134
Heston's Adoption Study in Oregon136
The Evidence from Denmark138
A Meta-Analysis of Offspring Risk140
Who Raised Schizophrenic Adoptees? The Kety Strategy142
Wender's Cross-Fostering Research146
Adoption Strategies in Finland147
Overview of Adoption Results148
8The Role of Psychosocial and Environmental Stressors150
Acute and Persistent Life Events152
The "New Look" in Family Influences155
Obstetrical Complications and Other Somatic Risks160
Seek Simplicity and Distrust It162
9Anguished Voices II: Personal Accounts of Family Members166
Making the Best of It167
A Father's Thoughts170
Confessions of a Schizophrenic's Daughter177
10Schizophrenia, Society, and Social Policy184
Patterns of Death and Physical Illness185
Criminality and Violence190
Sexuality, Marriage, Fertility, and Divorce193
Genetic Counseling197
Legal Constraints: Marriage, Immigration, and Sterilization204
The Nazi "Solution"207
A Parent's View on Enforcing Medication210
11The Big Picture214
Models as Maps: Where Are We and Where Do We Need to Go?216
Models for the Development of Schizophrenia: The Pathway from Genotype to Psychopathology218
Gene-Environment Models for the Transmission of Schizophrenia227
12What Next? The Decade of the Brain234
Neurobiology and Schizophrenia236
The Continuing Promise of Longitudinal High-Risk Studies239
Genetic Markers and Genetic Linkage242
A Story to End the Story247
Giving Love ... and Schizophrenia247
References and Bibliography256
Name Index285
Subject Index293

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