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This first-edition text clearly presents the fundamental principles of genetics, with an emphasis on the problem-solving skills crucial to understanding the complexity of genetics. Intended for undergraduate students in the biological sciences, it is designed to ground students in the basics of genetics, yet also enable them to explore more advanced and specialized subjects. Although the text does not presume an advanced knowledge of biology and chemistry, it does contain numerous examples of how the study of modern genetics rests upon these basic life sciences.
1. An Introduction to the Science of Genetics. Part 1: How Genes Are Organized and Transmitted Through Generations. 2. Transmission Genetics: Mendelian Analysis of Inheritance. 3. Genes, Chromosomes, and the Mechanism of Mendelian Inheritance. 4. Multiple Alleles and Gene Interactions. 5. Quantitative Traits and Polygenic Inheritance. 6. Linkage and Gene Mapping in Eukaryotes. 7. Extranuclear Inheritance. 8. The Genetics of Bacteria and Their Viruses. Part 2: How Genes Function At the Molecular Level. 9. The Physical Nature of DNA: Structure and Replication. 10. The Molecular Structure of Prokaryotic and Eukaryotic Chromosomes. 11. Transcription, Translation, and the Genetic Code. 12. Gene Cloning and Analysis. 13. Genomic Analysis and Modification. 14. Regulation of Gene Expression. 15. Developmental Genetics: Genetic Regulation of Cell Fate. 16. Developmental Genetics: Hierarchies of Genetic Regulation. Part 3: How Genes and Genomes Change and Evolve. 17. Gene Mutation and Repair. 18. Changes in Chromosome Number and Structure. 19. Recombination and Transposable Elements. 20. The Genetics of Cancer. 21. Population and Evolutionary Genetics. 22. Molecular Evolution. Appendix: Answers to Section Review Problems. Glossary. Index.