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Scleroderma

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Overview

Six Months After the First Edition of This Book, a small but significant clinical study of the therapy it describes was published in The Lancet. Performed at Harvard Medical School under the joint sponsorship of The Road Back Foundation and the National Institutes of Health, the study examined the effects of minocycline therapy on eleven patients suffering from this rare but increasingly common disease. The article reported nine of the patients improved substantially, and two-thirds of those completing the study ...
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Overview

Six Months After the First Edition of This Book, a small but significant clinical study of the therapy it describes was published in The Lancet. Performed at Harvard Medical School under the joint sponsorship of The Road Back Foundation and the National Institutes of Health, the study examined the effects of minocycline therapy on eleven patients suffering from this rare but increasingly common disease. The article reported nine of the patients improved substantially, and two-thirds of those completing the study were in full remission, free of all disease activity. No other therapy had ever come close to that kind of result. The full text of the Lancet article is in this new edition. Four out of five systemic scleroderma patients are women. One peer-reviewed study showed that two-thirds of its victims die within ten years of onset. Until recently, the disease was regarded by most physicians as untreatable, but by the end of the small Harvard study, five patients were in total remission, with no evidence of ongoing disease activity in their bodies. "I must admit we were pleasantly surprised," said principal investigator Dr. David Trentham. "It's safe and highly effective in a condition that previously had no real, definitive way of control."

The book offers a unique, insider's view of the Harvard research and its aftermath, beginning with a history of both the disease and the therapy, and including intimate life portraits of the first patients to recover. It also contains the first report from the on-going Serial Survey of the Long-Term Effects of Minocycline on Scleroderma, presented at the 8th Biennial Congress of the International Society for Rheumatic Therapies in Washington in mid 2002. A painful, disfiguring disease whose name means "hard skin," scleroderma afflicts some 400,000 Americans. In its systemic form, the disease often attacks the lungs, heart, kidneys, and liver. It also thickens the skin, causing pain and crippling disfigurement. Scleroderma brings major new insights -- and new hope -- to a previously obscure and bewildering medical mystery.

"Scleroderma, which affects as many as 400,000 Americans, starts off like skin cancer but is far more deadly... describes the first & only therapy to report reversal & remission of this deadly disease."

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Product Details

  • ISBN-13: 9781590770238
  • Publisher: M. Evans & Company
  • Publication date: 11/1/2003
  • Edition number: 2
  • Pages: 176
  • Sales rank: 492,821
  • Product dimensions: 5.61 (w) x 8.41 (h) x 0.55 (d)

Table of Contents

Foreword 5
Prologue 9
1 First Light 11
2 Portrait of a Disease 22
3 Onset 37
4 The Infectious Theory 57
5 Connections 65
6 Dr. Brown's Therapy 74
7 Pat Ganger's Road Back 87
8 A Husband's Story 93
9 What Return Can We Make? 98
10 Whistle 107
11 Pinch Me 127
12 Study Results 141
13 Is It Safe? 147
14 Tailoring the Therapy 155
15 In Defense of Heresy 162
16 What Happened Next 171
Addendum 1 Lancet Article on First Study 178
Addendum 2 Lancet Article on Second Study 181
Index 183
How to Help 188
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Customer Reviews

Average Rating 3.5
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Sort by: Showing 1 Customer Reviews
  • Anonymous

    Posted December 31, 2005

    The best book out there for this terrible disease

    My brother actually has this terrible disease and I believe that this book saved his life!! It led him to Dr. Trentham (in the book) and after 4years, he's nearly cured.Very informative, a must read for anyone that has scleroderma or knows someone with the disease.

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