Selection of the HPLC Method in Chemical Analysis

by Serban C. Moldoveanu, Victor David

Overview

Selection of the HPLC Method in Chemical Analysis serves as a practical guide to users of high-performance liquid chromatography and provides criteria for method selection, development, and validation.

High-performance liquid chromatography (HPLC) is the most common analytical technique currently practiced in chemistry. However, the process of finding the appropriate information for a particular analytical project requires significant effort and pre-existent knowledge in the field. Further, sorting through the wealth of published data and literature takes both time and effort away from the critical aspects of HPLC method selection.

For the first time, a systematic approach for sorting through the available information and reviewing critically the up-to-date progress in HPLC for selecting a specific analysis is available in a single book. Selection of the HPLC Method in Chemical Analysis is an inclusive go-to reference for HPLC method selection, development, and validation.

Product Details

ISBN-13:	9780128036846
Publisher:	Elsevier Science
Publication date:	11/14/2016
Pages:	598
Product dimensions:	7.50(w) x 9.25(h) x (d)

About the Author

Dr. Serban C. Moldoveanu is Senior Principal Scientist at R. J. Reynolds Tobacco Company. His research activity is focused on various aspects of chromatography including method development for the analysis by GC/MS, HPLC, and LC/MS/MS of natural products and cigarette smoke. He has also performed research on pyrolysis of a variety of polymers and small molecules. He has over 100 publications in peer reviewed journals, eleven books, and several chapter contributions. He is a member of the editorial board of the Journal of Analytical Methods in Chemistry.

Dr. Victor David is a Professor and Head of the Department of Analytical Chemistry, University of Bucharest, Romania. He is the author of more than 120 publications, including 92 scientific papers in ISI international journals and 10 books and chapters in various Encyclopedias. He is also a reviewer at several international journals.

Table of Contents

1. Start of the Implementation of a New HPLC Method2. Short Overviews of Analytical Techniques Not Containing an Independent Separation Step3. Short Overviews of the Main Analytical Techniques Containing a Separation Step4. Basic Information Regarding the HPLC Techniques5. Properties of Analytes and Matrices Determining HPLC Selection6. General Aspects Regarding the HPLC Analytical Column7. RP-HPLC Analytical Columns8. Polar Analytical Columns9. Stationary Phases and Columns for Ion Exchange, Ion-Moderated, and Ligand Exchange Chromatography10. Stationary Phases and Columns for Chiral Chromatography11. Stationary Phases and Columns for Size Exclusion12. Stationary Phases and Columns for Immunoaffinity Type Separations13. Solvents, Buffers, and Additives Used in the Mobile Phase14. Gradient Elution15. The Practice of HPLC

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From the Publisher

Serves as a practical guide to users of HPLC, providing exacting criteria for method selection, development, and validation