Self-Injurious Behavior: Gene-Brain-Behavior Relationships / Edition 1

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2002 Hardback NEW 9781557988850 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. *****PLEASE NOTE: This item ... is shipping from an authorized seller in Europe. In the event that a return is necessary, you will be able to return your item within the US. To learn more about our European sellers and policies see the BookQuest FAQ section***** Read more Show Less

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Self-Injurious Behavior is a comprehensive, interdisciplinary review o f the research on etiology and treatment of this chronic condition for which there is no known apparent cure. With an estimated prevalence rate of 13%, SIB occurs most frequently among persons who are retarded and autistic. In this volume, the field's leading researchers examin e a new generation of models and theories with a level of specificity far beyond what was heretofore imagined possible. From the burgeoning area of research on functional assessment and the behavioral and biol ogical antecedents of SIB, to the role of Lesch-Nyhan syndrome and opi oid peptides, the work of these foremost basic, applied, and behaviora l researchers is sure to greatly enhance fellow researchers', teachers ', and clinicians' understanding of this devastating condition.

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Editorial Reviews

From The Critics
A selection of 21 papers from two conferences. The first, in Rockville, Maryland (no date noted), focused on self-injurious behavior; the second, in San Diego in March 2000, on mental retardation and developmental disabilities. After an overview, they cover environmental mechanisms and intervention strategies, neurobiological factors, and Lesch-Nyhan syndrome as a model genetic disorder of self-injurious behavior. Annotation c. Book News, Inc., Portland, OR (
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Product Details

  • ISBN-13: 9781557988850
  • Publisher: American Psychological Association
  • Publication date: 1/28/2002
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 405
  • Product dimensions: 7.10 (w) x 10.10 (h) x 1.30 (d)

Table of Contents

I Overview of Self-Injurious Behavior 1
Ch. 1 Self-Injury: Knowing What We're Looking For 3
Ch. 2 Self-Injury and Comorbid Behaviors in Developmental, Neurological, Psychiatric, and Genetic Disorders 23
Ch. 3 Epidemiology of Self-Injurious Behavior in Mental Retardation: A Review 41
II Environmental Mechanisms and Intervention Strategies 79
Ch. 4 Treatment: Current Standards of Care and Their Research Implications 81
Ch. 5 Environmental Determinants of Self-Injurious Behavior 93
Ch. 6 Functional Assessment and Self-Restraint 105
Ch. 7 The Impact of Functional Assessment on the Treatment of Self-Injurious Behavior 119
Ch. 8 Evolution of Stereotypy Into Self-Injury 133
Ch. 9 Incidence of Self-Injurious Behavior: Birth to 3 Years 145
Ch. 10 Self-Injurious Behavior in Captive Macaque Monkeys 151
III Neurobiological Factors 163
Ch. 11 Dopaminergic Mechanisms in Self-Injurious Behavior and Related Disorders 165
Ch. 12 Pemoline and Other Dopaminergic Models of Self-Biting Behavior 181
Ch. 13 Opioids and the Maintenance of Self-Injurious Behavior 191
Ch. 14 Sleep and Cyclical Variables Related to Self-Injurious and Other Destructive Behaviours 205
Ch. 15 Self-Injury and Pain: Models and Mechanisms 223
Ch. 16 Temporal and Force Dynamics of Self-Injury 235
IV Lesch-Nyhan Syndrome as a Model Genetic Disorder of Self-Injurious Behavior
Ch. 17 Lessons From Lesch-Nyhan Syndrome 251
Ch. 18 Neuroimaging Studies in Lesch-Nyhan Syndrome and Lesch-Nyhan Variants 269
Ch. 19 Age-Dependent Reduction of Brain Dopamine: Relationship to Self-Injurious Behavior 279
Ch. 20 A New Animal Model for Lesch-Nyhan Syndrome: Calcium Channel Activation With Bay K 8644 289
Ch. 21 Replacement Therapy for the Treatment of Lesch-Nyhan Syndrome 299
References 309
Author Index 381
Subject Index 395
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