Self-Production of Supramolecular Structures: From Synthetic Structures to Models of Minimal Living Systems / Edition 1

Hardcover (Print)
Buy New
Buy New from
Used and New from Other Sellers
Used and New from Other Sellers
from $215.00
Usually ships in 1-2 business days
(Save 40%)
Other sellers (Hardcover)
  • All (8) from $215.00   
  • New (6) from $250.00   
  • Used (2) from $215.00   


How did life begin on the Earth? The units of life are cells, which can be defined as bounded systems of molecules that capture energy and nutrients from the environment — systems that expand, reproduce, and evolve over time, often into more complex systems. This book is the proceedings of a unique meeting, sponsored by NATO and held in Maratea, Italy, that brought together for the first time an international group of investigators who share an interest in how molecules self-assemble into supramolecular structures, and how those structures may have contributed to the origin of life.
The book is written at a moderately technical level, appropriate for use by researchers and by students in upper-level undergraduate and graduate courses in biochemistry and molecular biology. The overall interest of its subject matter provides an excellent introduction for students who wish to understand how the foundational knowledge of chemistry and physics can be applied to one of the most fundamental questions now facing the scientific community.
The editors are pioneers in defining what we mean by the living state, particularly the manner in which simple molecular systems can assume complex associations and functions, including the ability to reproduce. Each chapter of the book presents an up-to-date report of highly significant research. Two of the authors received medals from the National Academy of Science USA in 1994, and other research reported in the book has been featured in internationally recognized journals such Scientific American, Time, and Discover.

Read More Show Less

Editorial Reviews

Marking a moment when the field of self-replication has undergone considerable development in the past three or four years, partly because of contributions from different schools of thought, disciplines, and philosophies, 28 papers compare notes and confront differences not only on the subject of self-replication but on more fundamental questions concerning the definition of life and minimal life. They cover historical and philosophical perspectives, template chemistry, chirality, RNA, cell models, and a scattering of miscellaneous topics. Reproduced from typescripts. Annotation c. Book News, Inc., Portland, OR (
Read More Show Less

Product Details

  • ISBN-13: 9780792331636
  • Publisher: Springer Netherlands
  • Publication date: 9/6/2007
  • Series: Nato Science Series C: (closed), #446
  • Edition description: 1994
  • Edition number: 1
  • Pages: 317
  • Product dimensions: 9.21 (w) x 6.14 (h) x 0.81 (d)

Table of Contents

Introduction; P.L. Luisi. Historical and Philosophical Perspectives. Historical overview to the quest of self-reproduction and artificial life; S. Hoffmann. On defining life; F.J. Varela. A few precautionary words concerning terminology; G.R. Fleischaker. Template Chemistry. Molecular replication: From minimal to complex systems; D. Sievers, T. Achilles, J. Burmeister, S. Jordan, A. Terfort, G. von Kiedrowski. Self-replication and reproduction: From molecules to proells; E. Szathmáry. Extrabiotic replication and self-assembly; J. Rebek, Jr. The prebiotic synthesis and replication of RNA oligomers: the transition from prebiotic molecules to the RNA world; J.P. Ferris. Template-directed synthesis of oligomers: Kinetics vs thermodynamic control; J.T. Goodwin, P. Luo, J.C. Leitzel, D.G. Lynn. Chirality and Replication. Chirality and the first self-replicating molecules; A.W. Schwartz, M.J. Van Vliet. Are peptides possible support for self-amplification of sequence information? A. Brack. The RNA World. Minimonsters: Evolutionary by-products of in vitro RNA amplification; R.R. Breaker, G.F. Joyce. Models for the auatalytic replication of RNA; L. Giver, S. Lato, A. Ellington. RNA species that multiply indefinitely with RNA polymerase; C.K. Biebricher. Chemical oscillations and nonlinear chemical kinetics; P.V. Coveney. The Cell View and Cell Models. The chemical implementation of autopoiesis; P.L. Luisi. Molecular recognition in micelles; J.S. Nowick, J.S. Chen, T. Cao, G. Noronha. Self-reproducing vesicles; P. Walde. Sources and syntheses of prebiotic amphiphiles; D.W. Deamer. Ancient paralogous duplications and the search for Archean cells; V. García-Meza, A. González-Rodríguez, A. Lazcano. Posters. Self-replication of oligonucleotides in reverse micelles; C. Böhler, W. Bannwarth, P.L. Luisi. Liposomes from lipidonucleotides and from lipidopeptides; S. Bonaccio, C. Cescato, P. Walde, P.L. Luisi. Dendritic luminescent and redox-active supermolecules made of transition metal complexes; S. Campagna, G. Denti, S. Serroni, A. Juris, M. Venturi, V. Balzani. Layer-by-layer adsorption: the solid/liquid-interface as a template for the controlled growth of well defined nanostructures of polyelectrolytes, proteins, DNA and polynucleotides; G. Decher, J.-D. Hong, K. Lowack, Y. Lvov, J. Schmitt. Molecular recognition of amino acids by RNA; P. Burgstaller, D. Faulhammer, M. Famulok. Towards nature's structural guidelines: Conclusions on the unsolved structures of RNA-dependent RNA polymerases; D.L. Gerloff. A self-catalyzed (autopoietic) synthesis of an anionic surfactant: Experimental evidence and theoretical modeling; M. Fresta, M. Maestro, F. Mavelli. Competition, reciprocity, and mutation at the molecular level: Irradiation of a synthetic replicator generates a superior species; V. Rotello, Q. Feng, J.-I. Hong, J. Rebek, Jr. Giant vesicles; R. Wick, P. Walde, P.L. Luisi. Index.

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star


4 Star


3 Star


2 Star


1 Star


Your Rating:

Your Name: Create a Pen Name or

Barnes & Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation


  • - By submitting a review, you grant to Barnes & and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Terms of Use.
  • - Barnes & reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)