Semantic Web: Revolutionizing Knowledge Discovery in the Life Sciences / Edition 1

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The Semantic Web provides a common framework that allows data to be shared and reused across application, enterprise, and community boundaries. Advanced Semantic Web technologies are now enabling a wide range of tasks of central importance to the management of life science information. This book introduces these technologies to life science and bioinformatics professionals, illustrating their utility and highlighting their implementation in biological, medical and clinical scenarios. In six parts the book covers the topics of database and literature integration, knowledge representation, knowledge visualization, the utilization of formal knowledge representations, and access to distributed knowledge. The factors impacting on the establishment of the semantic web in life science and the legal challenges that will impact on its proliferation are addressed in the concluding part.

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Product Details

  • ISBN-13: 9780387484365
  • Publisher: Springer US
  • Publication date: 12/4/2006
  • Edition description: 2007
  • Edition number: 1
  • Pages: 446
  • Product dimensions: 9.21 (w) x 6.14 (h) x 1.06 (d)

Meet the Author

Christopher Baker is a Principle Investigator at the Knowledge Discovery Department of the Institute for Infocomm Research (I2R), a member of the Agency for Science, Technology and Research (A*STAR) in Singapore. Dr Baker was formerly Bioinformatics Project Manager of the Génome Québec funded project, ’Ontologies, the semantic web and intelligent systems for genomics’ where he coordinated the application of knowledge management technologies to fungal genomic data sets. Prior to this he was Group Leader In-silico Discovery at Ecopia BioSciences Inc. where he masterminded key portions of the DecipherIT™ bioinformatics software suite and managed the genomic annotation team. Dr Baker received post doctoral training at Iogen Corporation and the University of Toronto after completing his Ph. D. studies in Environmental Microbiology and Enzymology at the University of Wales, Cardiff, UK.

Dr. Cheung is currently an Associate Professor at the Center for Medical Informatics, Yale University School of Medicine. Dr. Cheung is a bioinformatician with a Ph.D. in Computer Science. He has established a broad base of collaboration with life scientists, computational biologists, and computer scientists. Dr. Cheung has published extensively in the field of bioinformatics. He is one of the core faculty members in the Yale Ph.D. Program in Computational Biology and Bioinformatics. In addition, he is a Principal Investigator of two research grants (one was awarded by the National Institutes of Health and the other was awarded by the National Science Foundation). Dr. Cheung’s research interests include biological database and tool integration. Recently, Dr. Cheung has embarked on the research and development of Semantic Web in the bioscience domain.

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Table of Contents

Introduction.- Part I: Database and Literature Integration.- Semantic Web Approach to Database Integration in the Life Sciences.- Querying Semantic Web Contents.- Knowledge Acquisition from the Biomedical Literature.- Part II: Biological Ontologies - Clinical Ontologies for Discovery Applications.- Ontology Engineering for Biological Applications.- The Evaluation of Ontologies: Toward Improved Semantic Interoperability.- OWL for the Novice: A Logical Perspective.- PART III: Ontology Visualization.- Techniques for Ontology Visualization.- On Visualization of OWL Ontologies.- PART IV: Ontologies in Action.- Applying OWL Reasoning to Genomics.- Can Semantic Web Technologies Enable Translational Medicine?.- Ontology Design for Biomedical Text Mining.- PART V: Using Distributed Knowledge.- SemBOWSER Semantic Biological Web Services Registry.- Agent Technologies in the Life Sciences.- Knowledge Discovery for Biology with Taverna.- PART VI: On the Success of Semantic Web in the Life Sciences.- Factors Influencing the Adoption of the Semantic Web in the Life Sciences.- Semantic Web Standards: Legal and Social Issues and Implications.

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