Skeletal Function and Form: Mechanobiology of Skeletal Development, Aging, and Regeneration

Paperback (Print)
Buy New
Buy New from
Used and New from Other Sellers
Used and New from Other Sellers
from $70.65
Usually ships in 1-2 business days
(Save 11%)
Other sellers (Paperback)
  • All (8) from $70.65   
  • New (6) from $70.65   
  • Used (2) from $74.12   


The intimate relationship between form and function inherent in the design of animals is perhaps nowhere more evident than in the musculoskeletal system. This book, about how function determines form, addresses the role of mechanical factors in the development, adaptation, maintenance, aging, and repair of skeletal tissues. The authors refer to this process as mechanobiology and develop their theme within an evolutionary framework. They show how degenerative disorders such as arthritis and osteoporosis are regulated by the same mechanical processes that influence normal development and growth. Skeletal Function and Form bridges important gaps among disciplines, providing a common ground for a multidisciplinary understanding.

Read More Show Less

Editorial Reviews

Journal of Bone and Joint Surgery
Anyone who is interested in any aspect of skeletal disorders and injuries can feel deeply indebted to these two fine authors for providing us with complete coverage and facilitating a clear understanding of the complex, sophisticated field of bioengineering and its related field of mechanobiology. I am confident that this outstanding book will become a classic.
From the Publisher
"...interesting and thought-provoking..." International Journal of Osteoarchaeology

"Overall it is a masterly treatment of the subject..." Journal of the Geological Magazine

"Excellent.... The text is concise, direct and erudite. ... This is an informative and enjoyable book..." Times Higher Education Supplement

"A terrific job...the authors have admirably achieved their ambitious objective of 'bridging important gaps between disciplines in a manner that will provide common ground for understanding and future investigation' by providing a 'single source in which these ideas are summarized'...I believe that all readers with an interest in skeletal form and function will gain new understanding of the possible roles of physical forces in skeletal tissue processes, will have ideas about new hypotheses to pose and test, and will be drawn to wonder about the physical, biological, and evolutionary mechanisms responsible for skeletal tissue function and form." Journal of Biomechanics

"A very detailed treatment of skeletal tissues and developmental mechanics. It is perfectly suited for students of functional anatomy or bioengineering, and those engaged in applied biomedical pursuits.... Skeletal Function and Form is a beautifully executed book that sticks to the point and makes its case. The reader is treated to a solid base of information that clarifies how mechanical factors impact development, and how function determines form. The book is well written and wonderfully illustrated, and it deserves a home on the bookshelf of anyone curious about the structure of the vertebrate skeleton." Palaios

"Technical and authoritative. It will be particularly useful to researchers and graduate students one step removed in their direct research interests from the topics covered. Readers interested in the mechanics of bone and cartilage as tissues will certainly find this a valuable resource." Richard J. Smith, American Journal of Human Biology

"The preface to Skeletal Function and Form states that the main goal of the book is to demonstrate that function determines form. In a wide variety of ways, the authors succeed admirably.... This book also has appeal for students of many biological disciplines because of the emphasis on evolutionary changes that affect organisms at many taxonomic levels.... It is at a level of sophistication and covers its intended ground in sufficient depth for serious students of biomechanics, evolutionary biology, and skeletal development and growth. As a functional morphologist, human anatomist, evolutionist, and vertebrate paleontologist, I found many answers to important questions that I have not seen addressed elsewhere, particularly discussed in a comparative, functional, and evolutionary context in a single location. I recommend the book as an excellent reference and an enjoyable read!" Journal of Mammalogy

Read More Show Less

Product Details

  • ISBN-13: 9780521714754
  • Publisher: Cambridge University Press
  • Publication date: 9/20/2007
  • Edition description: Reissue
  • Pages: 332
  • Product dimensions: 7.01 (w) x 10.00 (h) x 0.71 (d)

Table of Contents

Ch. 1 Form and Function 1
Ch. 2 Skeletal Tissue Histomorphology and Mechanics 31
Ch. 3 Cartilage Differentiation and Growth 53
Ch. 4 Perichondral and Periosteal Ossification 73
Ch. 5 Endochondral Growth and Ossification 106
Ch. 6 Cancellous Bone 138
Ch. 7 Skeletal Tissue Regeneration 161
Ch. 8 Articular Cartilage Development and Destruction 201
Ch. 9 Mechanobiology in Skeletal Evolution 235
Ch. 10 The Physical Nature of Living Things 265
App. A: Material Characteristics 267
App. B: Structural Characteristics 283
App. C: Failure Characteristics 292
Index 309
Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star


4 Star


3 Star


2 Star


1 Star


Your Rating:

Your Name: Create a Pen Name or

Barnes & Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation


  • - By submitting a review, you grant to Barnes & and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Terms of Use.
  • - Barnes & reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)