Skeletal Muscle Repair and Regeneration / Edition 1

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Overview

Skeletal muscle is the most abundant tissue of our body. Apart from its essential role in locomotion, it is also the body's main store of carbohydrate and protein as well as being one of the principle generators of heat. Its proper maintenance and function are, therefore, essential. A severe acute loss of muscle function is potentially lethal and the debilitating effects of chronic decline in mobility are commonplace experience, so repair and maintenance of the tissue must by both rapid and effective. Since the middle of the last century we have progressively built up a comprehensive descriptive model of the allied mechanisms that maintain our muscles at a size and strength appropriate to the functional demands upon them and that rapidly repair damaged muscles. This volume is an assemblage of the collective experience from the pick of major research groups investigating these aspects of muscle cell biology. The topics range from correlation of changes in pattern of gene expression with the histological sequence during a regenerative episode to the distinctive insult-specific patterns of structural and functional outcome at the other end of the spectrum. The middle ground - who is doing what in this complex process - constitutes the meat of this sandwich.

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Editorial Reviews

Doody's Review Service
Reviewer: Mark Gonzalez, MD (University of Illinois at Chicago College of Medicine)
Description: This advanced treatise on skeletal muscle regeneration includes contributions from authors from the United States and Europe.
Purpose: The book provides a broad discussion of skeletal muscle regeneration including historical aspects, animal models, stem cells, and reinnervation.
Audience: The audience includes researchers and clinicians who work in the field of myopathy and neuropathy. It is an advanced work and requires a background on the subject.
Features: The book is well written and comprehensive, the illustrations are adequate, and the references are up to date and complete.
Assessment: This multiauthored book on skeletal muscle regeneration is a good addition to the literature on this topic.
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Product Details

  • ISBN-13: 9781402067679
  • Publisher: Springer Netherlands
  • Publication date: 3/11/2008
  • Series: Advances in Muscle Research Series , #3
  • Edition description: 2008
  • Edition number: 1
  • Pages: 379
  • Product dimensions: 6.40 (w) x 9.30 (h) x 1.10 (d)

Table of Contents


Preface     vii
Contributors     xi
Myogenesis - The Early Years   Frank E. Stockdale     1
The Origin and Genetic Regulation of Myogenic Cells: From the Embryo to the Adult   Margaret Buckingham   Didier Montarras     19
The Muscle Satellite Cell: The Story of a Cell on the Edge!   Peter S. Zammit     45
Non Muscle Stem Cells and Muscle Regeneration   Graziella Messina   Stefano Biressi   Giulio Cossu     65
Transcriptional Cascades in Muscle Regeneration   Po Zhao   Eric Hoffman     85
The Ins and Outs of Satellite Cell Myogenesis: The Role of the Ruling Growth Factors   Gabi Shefer   Zipora Yablonka-Reuveni     107
Relaying the Signal During Myogenesis: Intracellular Mediators and Targets   Roddy S. O'Connor   Grace K. Pavlath     145
Muscle Regeneration in Animal Models   Bruce M. Carlson     163
Skeletal Muscle Reconstitution During Limb and Tail Regeneration in Amphibians: Two Contrasting Mechanisms   Elly M. Tanaka     181
Muscle Fibre Regeneration in Human Skeletal Muscle Diseases   George Karpati   Maria J. Molnar     199
Skeletal Muscle Repair After Exercise-Induced Injury   TeroA.H. Jarvinen   Minna Kaariainen   Ville Aarimaa   Markku Jarvinen   Hannu Kalimo     217
Inflammation in Skeletal Muscle Regeneration   James G. Tidball     243
Complexity of Extracellular Matrix and Skeletal Muscle Regeneration   Miranda D. Grounds     269
Innervation of Regenerating Muscle   Clarke R. Slater   Stefano Schiaffino     303
Boosting Muscle Regeneration   Tommaso Nastasi   Nadia Rosenthal     335
Age-Dependent Changes in Skeletal Muscle Regeneration   Andrew S. Brack   Thomas A. Rando     359
Index     375
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