BN.com Gift Guide

Smith and Williams' Introduction to the Principles of Drug Design and Action / Edition 3

Hardcover (Print)
Used and New from Other Sellers
Used and New from Other Sellers
from $35.97
Usually ships in 1-2 business days
(Save 64%)
Other sellers (Hardcover)
  • All (9) from $35.97   
  • New (3) from $115.00   
  • Used (6) from $35.97   
Close
Sort by
Page 1 of 1
Showing 1 – 2 of 3
Note: Marketplace items are not eligible for any BN.com coupons and promotions
$115.00
Seller since 2014

Feedback rating:

(194)

Condition:

New — never opened or used in original packaging.

Like New — packaging may have been opened. A "Like New" item is suitable to give as a gift.

Very Good — may have minor signs of wear on packaging but item works perfectly and has no damage.

Good — item is in good condition but packaging may have signs of shelf wear/aging or torn packaging. All specific defects should be noted in the Comments section associated with each item.

Acceptable — item is in working order but may show signs of wear such as scratches or torn packaging. All specific defects should be noted in the Comments section associated with each item.

Used — An item that has been opened and may show signs of wear. All specific defects should be noted in the Comments section associated with each item.

Refurbished — A used item that has been renewed or updated and verified to be in proper working condition. Not necessarily completed by the original manufacturer.

New
Brand new.

Ships from: acton, MA

Usually ships in 1-2 business days

  • Standard, 48 States
  • Standard (AK, HI)
$119.45
Seller since 2014

Feedback rating:

(310)

Condition: New
Brand New Item.

Ships from: Chatham, NJ

Usually ships in 1-2 business days

  • Canadian
  • International
  • Standard, 48 States
  • Standard (AK, HI)
  • Express, 48 States
  • Express (AK, HI)
Page 1 of 1
Showing 1 – 2 of 3
Close
Sort by

Overview

The third edition of this popular textbook provides a thorough introduction to the principles of rational drug design, adopting a "from the bench to the market place" approach.
As knowledge of biological systems has expanded and the number of techniques available for exploring and visualising their components has increased, it has become possible to design drugs specifically for a given target. This unique insight has revolutionised the process of drug development for specific disease states, and in this textbook both novel and established approaches are incorporated.
The principles of drug design are demonstrated using real examples, illustrating the discovery of "lead" compounds and their manipulation to produce nontoxic drug candidates, which will successfully interact with target receptors in a predicted fashion. In addition to fully up-dating the previous edition, important new sections on the pharmacological consequences of drug chirality, agonists and antagonists of neurotransmitters, a

Disc. technical/biological advances; research design & multidisciplinary teams; regulatory environment.

Read More Show Less

Editorial Reviews

Booknews
The third edition of this textbook provides an introduction to the principles of rational drug design, tracing the process from the bench to the market place. Both novel and established approaches to drug design are considered, and the principles of design are explained using real examples. In addition to updating the contents of the previous edition, Smith (pharmacy, University of Wales) has added sections on the pharmacological consequences of drug chirality, agonists and antagonists of neurotransmitters, and the process involved in proceeding from program sanction to clinical trials. Annotation c. Book News, Inc., Portland, OR (booknews.com)
Read More Show Less

Product Details

  • ISBN-13: 9789057020377
  • Publisher: CRC Press
  • Publication date: 5/15/1998
  • Edition description: Older Edition
  • Edition number: 3
  • Pages: 568
  • Product dimensions: 6.72 (w) x 10.28 (h) x 1.50 (d)

Table of Contents

Processes of Drug Handling by the Body
The Design of Drug Delivery Systems
Intermolecular Forces and Molecular Modelling
Chirality of Drugs and Its Pharmacological Consequences
Quantitative Structure-Activity Relationships and Drug Design
From Programme Sanction to Clinical Trials: A Practical View of the Quest for Arimidex(tm), a Potent Selective Inhibitor of Aromatase
Pro-Drugs
Enzyme Inhibitors as Drugs
The Chemotherapy of Cancer
Neurotransmitters: Agonists and Antagonists
Design of Antimicrobial Chemotherapeutic Agents
Recombinant DNA Technology: Monoclonal Antibodies
Bio-inorganic Chemistry and Its Pharmaceutical Applications
Adolescents in our Midst
Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)