Solid-State Fermentation Bioreactors: Fundamentals of Design and Operation / Edition 1

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This concise professional reference provides a fundamental framework for the design and operation of solid-state fermentation bioreactors, enabling researchers currently working at laboratory scale to scale-up their processes. After surveying the main bioreactor types currently used in solid-state fermentation, it focuses on the mathematical modeling of bioreactors, which is covered in three parts. Firstly, the book shows how to plan a research program in order to characterize the growth kinetics in a manner appropriate for incorporation into bioreactor models. Secondly, it addresses the heat and mass transfer phenomena that occur in solid-state fermentation bioreactors and the mathematical expressions that are used to describe them. Thirdly it demonstrates, through a number of case studies, how mathematical models can be used in the optimization of bioreactor performance. The final part of the book addresses several issues closely related with bioreactor operation, namely process monitoring equipment, process control strategies and the selection of an appropriate air preparation system.

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Product Details

  • ISBN-13: 9783642068393
  • Publisher: Springer Berlin Heidelberg
  • Publication date: 11/9/2010
  • Edition description: Softcover reprint of hardcover 1st ed. 2006
  • Edition number: 1
  • Pages: 448
  • Product dimensions: 0.98 (w) x 9.21 (h) x 6.14 (d)

Table of Contents

Solid-State Fermentation Bioreactor Fundamentals: Introduction and Overview.- The Bioreactor Step of SSF: A Complex Interaction of Phenomena.- to Solid-State Fermentation Bioreactors.- Basics of Heat and Mass Transfer in Solid-State Fermentation Bioreactors.- The Scale-up Challenge for SSF Bioreactors.- Group I Bioreactors: Unaerated and Unmixed.- Group II Bioreactors: Forcefully-Aerated Bioreactors Without Mixing.- Group III: Rotating-Drum and Stirred-Drum Bioreactors.- Group IVa: Continuously-Mixed, Forcefully-Aerated Bioreactors.- Group IVb: Intermittently-Mixed Forcefully-Aerated Bioreactors.- Continuous Solid-State Fermentation Bioreactors.- Approaches to Modeling SSF Bioreactors.- Appropriate Levels of Complexity for Modeling SSF Bioreactors.- The Kinetic Sub-model of SSF Bioreactor Models: General Considerations.- Growth Kinetics in SSF Systems: Experimental Approaches.- Basic Features of the Kinetic Sub-model.- Modeling of the Effects of Growth on the Local Environment.- Modeling of Heat and Mass Transfer in SSF Bioreactors.- Substrate, Air, and Thermodynamic Parameters for SSF Bioreactor Models.- Estimation of Transfer Coefficients for SSF Bioreactors.- Bioreactor Modeling Case Studies: Overview.- A Model of a Well-mixed SSF Bioreactor.- A Model of a Rotating-Drum Bioreactor.- Models of Packed-Bed Bioreactors.- A Model of an Intermittently-Mixed Forcefully-Aerated Bioreactor.- Instrumentation for Monitoring SSF Bioreactors.- Fundamentals of Process Control.- Application of Automatic Control Strategies to SSF Bioreactors.- Design of the Air Preparation System for SSF Bioreactors.- Future Prospects for SSF Bioreactors.

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