Somitogenesis, Part I

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Somitogenesis, Part 1 and Part 2 provides a broad perspective on the novel strategies and conceptual paradigms that drive the current resurgence of interest in somitogenesis—the process by which somites form and elaborate differentiated tissues and structures. Because somites are a ubiquitous feature of vertebrate embryos, they can be studied in a variety of experimental animal models including those amenable to genetic studies (zebrafish, mammalian), molecular/genetic studies (mammalian, avian), as well as those...

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Overview

Somitogenesis, Part 1 and Part 2 provides a broad perspective on the novel strategies and conceptual paradigms that drive the current resurgence of interest in somitogenesis—the process by which somites form and elaborate differentiated tissues and structures. Because somites are a ubiquitous feature of vertebrate embryos, they can be studied in a variety of experimental animal models including those amenable to genetic studies (zebrafish, mammalian), molecular/genetic studies (mammalian, avian), as well as those already well established for classical experimental embryological and cell biological studies (amphibians, avian). The wide variety of experimental approaches to somitogenesis that are presented in these companion volumes will leave the reader with a broad perspective on how current research in somitogenesis is helping to solve fundamental questions in vertebrate development and morphogenesis.
Highlights:
• Novel transcriptional mechanisms that control repetitive pattern formation
• Wide-scale genetic screens for mutations affecting somitogenesis
• Molecular/genetic control of pattern and tissue formation during somitogenesis
• Transplantation of mouse embryo somites
• Classical embryological approaches and concepts
• Evolutionary perspectives on somitogenesis

Audience: Graduate students and researchers in developmental biology, cellular biology, genetics, molecular biology, and neuroscience.

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Editorial Reviews

Booknews
Continues the series' custom of addressing developmental mechanisms in a variety of experimental systems. Topics include the murine allantois; axial relationships between egg and embryo in the mouse; maternal control of pattern formation in early embryos; eye development in ; the development of voltage-gated ion channels and its relation to activity-dependent developmental events; molecular regulation of neuronal apoptosis; a novel protein for Ca2+ signaling at fertilization; and the development of the kidney. Annotation c. by Book News, Inc., Portland, Or.
Booknews
Addresses basic biological developmental mechanisms, many of which seem to be the same, for example, in arthropods and vertebrates, and in yeast and mammals. Begins with the lower eukaryotes and progresses through plants and animals of increasing complexity, discussing such topics as embryogenesis, cell differentiation and adhesion, and axis determination in vertebrate embryos. Annotation c. Book News, Inc., Portland, OR (booknews.com)
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Product Details

  • ISBN-13: 9780121531478
  • Publisher: Elsevier Science
  • Publication date: 12/7/1999
  • Series: Current Topics in Developmental Biology Series
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 319
  • Product dimensions: 6.31 (w) x 9.34 (h) x 0.90 (d)

Table of Contents

P.P.L. Tam, D. Goldman, A. Camus, and G.C. Schoenwolf, Early Events of Somitogenesis in Higher Vertebrates: Allocation of Precursor Cells during Gastrulation and Organization of a Meristic Pattern in the Paraxial Mesoderm.
S. Eloy-Trinquet, L. Mathias, and J.-F. Nicolas, Retrospective Tracing of the Developmental Lineage of the Mouse Myotome.
O. Pourquié, Segmentation of the Paraxial Mesoderm and Vertebrate Somitogenesis.
C.D. Stern and D. Vasiliauskas, Segmentation: A View from the Border.
A. Rawls, J. Wilson-Rawls, and E.N. Olson, Genetic Regulation of Somite Formation.
A.C. Burke, Hox Genes and the Global Patterning of the Somitic Mesoderm.
R. Keller, The Origin and Morphogenesis of Amphibian Somites.
S.A. Holley and C. Nüsslein-Volhard, Somitogenesis in Zebrafish.
M. Bronner-Fraser, Rostrocaudal Differences within the Somites Confer Segmental Pattern to Trunk Neural Crest Migration.
Index.
Contents of Previous Volumes.

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