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More About This Textbook
Overview
Originally published in 2006, this is a comprehensive and definitive account of the human male gamete. The volume summarizes many unique and revealing characteristics of the sperm cell. It provides a detailed overview of human sperm production, maturation and function, and looks at how these processes affect and influence fertility, infertility and ART. The volume thus provides a detailed review of the most important research and developments, augmented with pertinent references. This book will appeal to all practitioners and scientists in reproductive medicine and in particular to clinical scientists, graduate and post-graduate scientists, and laboratory personnel.
Editorial Reviews
From The Critics
Reviewer: Anthony J Caruso, MD, MPH(University of Chicago Pritzker School of Medicine)Description: This is an authoritative summary of the latest research on the male gamete. It is a well organized presentation of the current state of human sperm production, maturation, and function and how these parameters influence fertility.
Purpose: The purpose is to summarize the latest investigation of the human male gamete. As the first comprehensive volume on this subject in a decade, it is long overdue. The authors have gathered an august collection of contributors who elegantly detail the molecular and genetic characteristics of both the competent and dysfunctional sperm genome complex.
Audience: The book is designed to appeal to all scientists and practitioners in reproductive medicine and, specifically, to clinical scientists, graduate and postgraduate scientists, and laboratory personnel. It addresses this wide ranging audience well in giving both an overview of the sperm cell as well as detailed reviews of the molecular and genomic components that each of these groups would find of interest.
Features: The scholarly articles reflect discussions of basic sperm function, as well as controls of sperm production and function. It concludes with a series of articles defining the current state of genetic analysis of sperm cells. Its breadth is impressive, both as a general review and as a basis for further study and research. A centrally placed series of color plates illustrate the discussion particularly well.
Assessment: This is a terrific addition to the field of andrology. The editors have taken a subject that is expanding rapidly and compressed it in a smoothly organized volume that will stimulate thought and research.
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Table of Contents
1. Anatomical and compartmental analysis Peter Sutovsky and Gaurishankar Manandhar; 2. Sperm chromatin stability and susceptibility to damage in relation to its structure Jeffrey A. Shaman and W. Steven Ward; 3. Genomic and proteomic approaches to defining sperm production and function Sarah Conner, Linda Lefièvre and Christopher L. R. Barratt; 4. The epididymis and sperm maturation Trevor Cooper and C. H. Yeung; 5. Control of motility Claude Gagnon and Eve de Lamirande; 6. Regulation of capacitation Pablo Visconti and B. M. Gadella; 7. ROS's: friend or foe John Aitken and Liga Bennetts; 8. Testing sperm manufacturing quality: the sperm-zona binding assay Sergio Oehninger and Daniel Franken; 9. Genetics: a basic science perspective Peter Vogt; 10. Sex chromosome abnormalities and male infertility: a clinical perspective Shai Shefi and Paul J. Turek; 11. Epigenetic patterning in male germ cells: importance of DNA methylation to progeny outcome Jacquetta Trasler and Sophie La Salle; 12. The DAZ gene family and human germ cell development from embryonic stem cells Mark S. Fox, Renee A. Reijo Pera and Amander T. Clark; Index.