Spikes: Exploring the Neural Code / Edition 1

Paperback (Print)
Buy New
Buy New from BN.com
Used and New from Other Sellers
Used and New from Other Sellers
from $33.14
Usually ships in 1-2 business days
(Save 30%)
Other sellers (Paperback)
  • All (13) from $33.14   
  • New (6) from $35.81   
  • Used (7) from $33.14   


What does it mean to say that a certain set of spikes is the right answer to a computational problem? In what sense does a spike train convey information about the sensory world? Spikes begins by providing precise formulations of these and related questions about the representation of sensory signals in neural spike trains. The answers to these questions are then pursued in experiments on sensory neurons.Intended for neurobiologists with an interest in mathematical analysis of neural data as well as the growing number of physicists and mathematicians interested in information processing by "real" nervous systems, Spikes provides a self-contained review of relevant concepts in information theory and statistical decision theory.

Characterizing neural response, information transmission w/ spike trains, conditional mean as optimal estimator, etc.

Read More Show Less

What People Are Saying

From the Publisher
"A joy to read.... This book will undoubtedly become a classic. Theideas presented in it have already begun (in no small part through thework of the authors) to reshape our views of the neural code. Thisbook will make them accessible to a much wider audience." Anthony Zador ,Science

"Spikes is a really wonderful book. The particulartheory about how the brain works that informs the presentation, and thusdetermines how neural coding is to be described, is clearly thought throughand the arguments are attractively and intelligently presented." Charles F. Stevens, The Salk Institute

Read More Show Less

Product Details

  • ISBN-13: 9780262681087
  • Publisher: MIT Press
  • Publication date: 6/25/1999
  • Series: Computational Neuroscience
  • Edition description: Reprint
  • Edition number: 1
  • Pages: 408
  • Product dimensions: 7.00 (w) x 8.90 (h) x 0.90 (d)

Table of Contents

Series Foreword
Ch. 1 Introduction 1
Ch. 2 Foundations 19
Ch. 3 Quantifying information transmission 101
Ch. 4 Reliability of computation 189
Ch. 5 Directions 255
Epilogue: Homage to the single spike 279
Appendix Mathematical asides 281
References 369
Index 389
Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star


4 Star


3 Star


2 Star


1 Star


Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation


  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously
Sort by: Showing 1 Customer Reviews
  • Anonymous

    Posted May 19, 2000

    Neurobiology takes an unexpected hit from a bat out of ...

    How fast can a bat make up its mind? With its refined sonar system, a bat can detect a looming obstruction and swerve to avoid it in a split second. Experiments show that the bat has time to process only one spike, or nerve impulse, in the available time window. This is impressive, but it calls into question the long established idea that the nervous system measures and communicates information (to the brain) as a function of the time intervals between spikes. It takes two spikes to open and close a time interval. For the bat, using just one spike to make its decision, there exists no interval to measure. Somehow, a single spike is - after all -- capable of conveying information to the brain. This very surprising news was revealed not only in the bat experiments, but by a substantial body of experimental results that have filtered into the literature over time. This book gathers them up and then asks anew: How does a nerve convey information about the world toward the brain? What's the real code? It is a crucially important question - one of the most important questions in human history, in fact -- because before one can make workable theories about how a brain works, one must know what sorts of signals it receives and acts upon. The authors offer and review alternative codes, but one answer seems quite transparent. The shocking secret of neural encoding is that there is no secret -- no code. A single spike conveys information. No computation or decipherment is required to extract it. But how? The pulse cannot be amplitude modulated (this is an absolute). But it can surely do many other clever things that would elude detection by the instruments used to study nerve impulses. The impulse could spin. Or wobble. It could and probably does travel up the axon membrane in one of many discrete longitudinal channels, formed by protein links between adjacent ion channels. In such a nerve the information, or sensory increment level, is inherent in the channel number. By all means, read spikes for the many fresh ideas it cuts loose. All in a calm, measured and very sensible tone of voice.

    Was this review helpful? Yes  No   Report this review
Sort by: Showing 1 Customer Reviews

If you find inappropriate content, please report it to Barnes & Noble
Why is this product inappropriate?
Comments (optional)