Statistical and Methodological Aspects of Oral Health Research / Edition 1

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Statistical and Methodological Aspects of Oral Health Research provides oral health researchers with an overview of the methodological aspects that are important in planning, conducting and analyzing their research projects whilst also providing biostatisticians with an idea of the statistical problems that arise when tackling oral health research questions.
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Editorial Reviews

From the Publisher

"In summary, this book is very well written. Its first three parts and the final part will be invaluable to dentists who are embarking on a clinical research project for the first time. In the reviewer's opinion, Part IV is more suitable for those undertaking doctoral studies or who have significant previous research experience." (Primary Dental Care, July 2010)

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Product Details

  • ISBN-13: 9780470517925
  • Publisher: Wiley
  • Publication date: 4/28/2009
  • Series: Statistics in Practice Series
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 410
  • Product dimensions: 6.20 (w) x 9.20 (h) x 1.00 (d)

Meet the Author

Emmanuel Lesaffre, Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Catholic University Leuven, Belgium. and University Hasselt, Belgium; Department of Biostatistics, Erasmus MC, Rotterdam, the Netherlands

Jocelyne Feine, Oral Health and Society Research Unit, Faculty of Dentistry, McGill University, Quebec, Canada.

Brian Leroux,Departments of Biostatistics and of Dental Public Health Sciences, University of Washington, Seattle, USA.

Dominique Declerck, School for Dentistry, Catholic University Leuven, Belgium.

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Table of Contents

List of Contributors ix

Preface xiii

Part I 1

1 Do We Need to Improve Oral Health Research? Dominique Declerck Emmanuel Lesaffre 3

2 Grading Evidence with a Focus on Etiology, Surrogates, and Clinical Devices Philippe Hujoel 13

3 The Effective use of Research Data for Evidence-Based Oral Health Care Ian Needleman Helen Worthington 27

Part II 45

4 Planning a Research Project Timothy A. DeRouen Donald E. Mercante 47

5 How to Carry out Successful Clinical Studies: Lessons from Project Management Jocelyne S. Feine Stephanie D. Wollin Faahim Rashid 61

6 Design and Analysis of Randomized Clinical Trials in Oral Health Brian Leroux Emmanuel Lesaffre 79

7 Epidemiological Oral Health Studies: Aspects of Design and Analysis Jimmy Steele Mark Pearce 97

8 Qualitative Research Christophe Bedos Pierre Pluye Christine Loignon Alissa Levine 113

9 Data Validity and Quality Finbarr Allen Jimmy Steele 131

Part III 145

10 Start with the Basics Manal A. Awad Nico Nagelkerke Emmanuel Lesaffre 147

11 Statistical Methods for Studying Associations Between Variables Brian G. Leroux 183

12 Assessing Accuracy of Oral Health Diagnostic Tests Todd A. Alonzo Peter J. Giannini 205

Part IV 219

13 Analysis of Correlated Responses Melissa D. Begg 221

14 Missing Data and Informative Cluster Sizes Stuart A. Gansky John M. Neuhaus 241

15 Failure Time Analysis Thomas A. Gerds Vibeke Qvist J&oumlet;rg R. Strub Christian B. Pipper Thomas H. Scheike Niels Keiding 259

16 Misclassification and Measurement Error in Oral Health Helmut K&uumlet;chenhoff 279

17 Statistical Genetics Amy D. Anderson 295

18 The Bayesian Approach Emmanuel Lesaffre Arno&sbreve;t Komárek AlejandroJara 315

Part V 339

19 Examples from Oral Health Epidemiology: The Signal Tandmobiel and Smile for Life studies Dominique Declerck Emmanuel Lesaffre Roos Leroy Jackie Vanobbergen 341

20 Subantimicrobial-dose Doxycycline Effects on Alveolar Bone Loss in Postmenopausal Women: Example of a Randomized Controlled Clinical Trial Julie A. Stoner Jeffrey B. Payne 359

Index 377

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