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From The CriticsReviewer: Laura E Power, MS (Oregon State University)
Description: This is a both a textbook to educate toxicologists and pharmacologists in statistics and experimental design and a resource to guide professional toxicologists and pharmacologists through statistics and experimental design. It contains relevant problem sets with solutions.
Purpose: The purpose is to educate and serve as a resource in statistics and experimental design for toxicologists. In addition to presenting an example problem for each technique discussed, basic SAS examples are included in this edition. These objectives are worthy. Toxicologists are educated in several fields of science, and their work involves applying statistics and experimental design. This book leads a researcher through an experimental design, providing guidance on which statistical tests should be used. The book meets the author's objectives by clarifying the decision process for choosing experimental and statistical design, while providing educational background.
Audience: This book is written for student and practicing toxicologists. The author is a credible authority in educating toxicologists in statistics and experimental design. He has 30 years of experience in toxicology and statistics and has authored 29 books.
Features: The book begins by introducing statistical concepts. It then presents an overview of computational hardware and software, and presents a helpful decision tree for selecting statistical techniques. Techniques are then presented, followed by a review of data analysis applications in toxicology. The book ends with an introduction to good laboratory practices and an overview of controversial areas. The decision tree for selecting statistical techniques is extremely helpful for practicing toxicologists. It is organized well to lead the reader to book sections relevant to satisfying their research objectives. A shortcoming of the decision tree is that it does not always include all options for appropriate statistical tests. For example, in the box in Figure 2.4 that directs the reader to use the Wilcoxon Rank Sum Test, the Mann-Whitney U Test would also be appropriate. However, the text describing the Mann-Whitney U Test (pp. 70-71) does indicate that it was not included in the decision tree.
Assessment: This is useful for educating toxicologists and as a resource for practicing toxicologists. It is organized in such a way that readers can pick up the book and quickly decide on the appropriate analytical techniques for their research. This edition incorporates computational techniques in statistics, which is very useful for the modern toxicologist.