Stem Cell and Gene-Based Therapy: Frontiers in Regenerative Medicine / Edition 1by Alexander Battler, Jonathan Leor
Pub. Date: 12/23/2005
Publisher: Springer London
The inability of the human body to be able significantly to self repair injured organs and tissues results in a considerable medical and social problem. During the last few years there has been incredible progress, and the achievements in experimental strategies for tissue regeneration, particularly in cell transplantation and stem cell research, have led to
The inability of the human body to be able significantly to self repair injured organs and tissues results in a considerable medical and social problem. During the last few years there has been incredible progress, and the achievements in experimental strategies for tissue regeneration, particularly in cell transplantation and stem cell research, have led to potential treatment options for many otherwise fatal conditions. These innovations hold promise for treating or preventing end-stage organ failure; cell therapy and tissue engineering of viable grafts with the potential to grow and remodel could provide prospective new solutions to the serious problems of organ donor shortage. Regenerative medicine stem cell and gene-based therapy offers a new approach for restoring function of damaged organs and tissues. Several books have been published on particular aspects of organ and/or tissue replacement but none cover the major new aspects and field of regenerative medicine. This title is therefore a timely addition to the literature. It brings together the major approaches to regenerative medicine in one text, which ensures that techniques learnt in one discipline are disseminated across other areas of medicine, allowing practitioners to gain knowledge not only of how regenerative medicine applies to their discipline directly but also how it could benefit their patients in the years to come.
- Springer London
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- 7.01(w) x 10.00(h) x 0.28(d)
Table of ContentsHeart: Introduction.- Renovation of the Injured Heart with Myocardial Tissue Engineering.- Adult Stem Cells for Myocardial Tissue Repair.- Regeneration of the Functional Myocardium Using Human Embryonic Stem Cells.- Therapeutic Angiogenesis.- Cell Therapy for Heart Failure.- Neuro: Introduction.- Cell Transplantation for Diseases of Myelin.- Stem Cells as a Source for Cell Replacement in Parkinson’s Disease.- Cell Replacement Therapy in Acute Stroke: Current State.- Gene Therapy to the Nervous System.- Musculoskeletal: Introduction.- Mesenchymal Stem Cells: Where Can You Find Them? How Can You Use Them?- Basic to Clinical Cartilage Engineering, Past, Present and Future Discussions.- Cartilage.- Bone Regeneration.- Osteoarthritis and Mesenchymal Cells – The Prospects for Repair of the Disease by Cell Transplantation and Tissue Engineering.- Kidney.- Introduction.- Progenitor Cell Therapy for Kidney Regeneration.- Tissue Engineering: The Bladder.- Eye.- Introduction.- Neuroprotection in Ophthalmology: A Review.- Autoimmunity for CNS Maintenance, Regeneration and Renewal: Development of a T Cell-Based Vaccination Against Neurodegeneration.- Retinal Repair by Stem Cell Transplantation.- Induction of Ocular Surface Regeneration.- Pancreas.- Introduction.- Insulin-Producing Cells Generated from Non-Pancreatic Tissues Islets from Pancreatic Progenitor Cells (Duct, Islet, and Exocrine).- Generation of Islets from Pancreatic Progenitor Cells.- Embryonic Stem Cells as a Source of Pancreatic Precursors and Islet Cells in Vitro.- Hematology.- Introduction.- Human Umbilical Cord Blood Transplantation: A viable Option for Stem Cell Graft.- Nonmyeloablative Stem-Cell Transplantation in the Treatment of Hematological Malignancies.- Haematopoietic Stem Cell Transplantation from HLA Haploidentical Donor.- Skin.- Introduction.- Wound Healing and Skin Substitutes.- Skin Regeneration From Multipotent Adult and Embryonic Stem Cells.
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